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ASSAY DEVELOPMENT: AN OVERVIEW Developing top-notch assays is pivotal to drug discovery and development. The better the developed assays, the fewer potential problems in subsequent stages of the research and development process.Proper assay development requires carefully considering multiple factors, including relevance, reproducibility, quality, interference and cost. Factor. A SKIN TEST TO MEASURE T-CELL IMMUNITY TO SARS-COV-2 SL: The TNX-2100 skin test is designed to measure T cell immunity using delayed-type hypersensitivity (DTH). DTH is the classic measure of antigen-specific T cell protection that has been in use for more than a century. The TNX-2100 skin test consists of three different mixtures of synthetic peptides designed to represent different protein ENGINEERING MICROBES TO HELP THE ENVIRONMENT There's a lot of interest right now in how different microbiomes--like the one made up of all the bacteria in our guts--could be harnessed to boost human health and cure disease. GENETIC FORM OF ALS THAT TARGETS CHILDREN IS IDENTIFIED A new study of over 3000 people has shown for the first time that a single biomarker can accurately indicate the presence of underlying neurodegeneration in people with cognitive issues. The US Food and Drug Administration today (June 7) announced the results of their investigation into Biogen’s SARS-COV-2: EXPERIMENTAL ANTIVIRAL THERAPY COULD REDUCE An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome. INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases FUNGI AND BACTERIA CAN ACTIVATE GENES LINKED TO HEAD AND An in vitro study demonstrates how fungi and bacteria can activate genes linked to head and neck tumors. The researchers revealed that the metabolism of biofilms stimulates cancer cells by favoring specific cell signaling pathways associated with the development of tumors and drug resistance. THE ETHICS AND SAFETY OF COVID-19 VACCINE PASSPORTS Vaccine passports also have the potential to prevent harms caused by lockdowns which, up to recently, were a required public health intervention against the COVID-19 pandemic. However, to ensure that health inequalities, on a national and international level, are not exacerbated, there are practical and ethical challenges that must beaddressed
PAN-CORONAVIRUS VACCINE BLOCKS SARS-COV-2 AND VARIANTS IN We think that's why this vaccine is effective against SARS-CoV-1, SARS-CoV-2 and at least four of its common variants, plus additional animal coronaviruses." "There have been three coronavirus epidemics in the past 20 years, so there is a need to develop effective vaccines that can target these pathogens prior to the next pandemic," Haynessaid.
CLINICAL TRIAL OF UNIVERSAL FLU VACCINE LAUNCHED BY THE Clinical Trial of Universal Flu Vaccine Launched by the NIH. Credit: CDC on Unsplash. A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of HealthClinical
IMPROVING OUR UNDERSTANDING OF THE LINK BETWEEN INDOOR AND People spend about 80-90% of their time indoors. Compared to outdoor air quality, indoor air quality is more relevant to people's health. Therefore, understanding the levels, sources and evolution of particulate matter (PM) indoors is important for the accurate evaluation of people's health risks to aerosol exposure. TYPES OF ION DETECTOR FOR MASS SPECTROMETRY HOW SCIENCE IS HELPING TO SOLVE THE FOOD WASTE CRISIS A few pounds of damaged fruit here, a couple of uneaten sides left behind at a restaurant there. It may not seem like much, but it adds up. In fact, it amounts to nearly one billion tons of wasted food per year globally according to the United Nations Environment Program. The situation is particularly dire in the United States, where food waste comprises 22% of municipal solid waste —the GUT MICROBE GENES LINKED TO AN ARRAY OF HUMAN DISEASES The findings, to be published May 18 in Nature Communications, link sets of bacterial genes to the presence of coronary artery disease, cirrhosis of the liver, inflammatory bowel disease, colon cancer, and type 2 diabetes. The analysis indicates that three of these conditions--coronary artery disease, inflammatory bowel disease, andliver
SARS-COV-2: EXPERIMENTAL ANTIVIRAL THERAPY COULD REDUCE An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome. INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases FUNGI AND BACTERIA CAN ACTIVATE GENES LINKED TO HEAD AND An in vitro study demonstrates how fungi and bacteria can activate genes linked to head and neck tumors. The researchers revealed that the metabolism of biofilms stimulates cancer cells by favoring specific cell signaling pathways associated with the development of tumors and drug resistance. THE ETHICS AND SAFETY OF COVID-19 VACCINE PASSPORTS Vaccine passports also have the potential to prevent harms caused by lockdowns which, up to recently, were a required public health intervention against the COVID-19 pandemic. However, to ensure that health inequalities, on a national and international level, are not exacerbated, there are practical and ethical challenges that must beaddressed
PAN-CORONAVIRUS VACCINE BLOCKS SARS-COV-2 AND VARIANTS IN We think that's why this vaccine is effective against SARS-CoV-1, SARS-CoV-2 and at least four of its common variants, plus additional animal coronaviruses." "There have been three coronavirus epidemics in the past 20 years, so there is a need to develop effective vaccines that can target these pathogens prior to the next pandemic," Haynessaid.
CLINICAL TRIAL OF UNIVERSAL FLU VACCINE LAUNCHED BY THE Clinical Trial of Universal Flu Vaccine Launched by the NIH. Credit: CDC on Unsplash. A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of HealthClinical
IMPROVING OUR UNDERSTANDING OF THE LINK BETWEEN INDOOR AND People spend about 80-90% of their time indoors. Compared to outdoor air quality, indoor air quality is more relevant to people's health. Therefore, understanding the levels, sources and evolution of particulate matter (PM) indoors is important for the accurate evaluation of people's health risks to aerosol exposure. TYPES OF ION DETECTOR FOR MASS SPECTROMETRY HOW SCIENCE IS HELPING TO SOLVE THE FOOD WASTE CRISIS A few pounds of damaged fruit here, a couple of uneaten sides left behind at a restaurant there. It may not seem like much, but it adds up. In fact, it amounts to nearly one billion tons of wasted food per year globally according to the United Nations Environment Program. The situation is particularly dire in the United States, where food waste comprises 22% of municipal solid waste —the GUT MICROBE GENES LINKED TO AN ARRAY OF HUMAN DISEASES The findings, to be published May 18 in Nature Communications, link sets of bacterial genes to the presence of coronary artery disease, cirrhosis of the liver, inflammatory bowel disease, colon cancer, and type 2 diabetes. The analysis indicates that three of these conditions--coronary artery disease, inflammatory bowel disease, andliver
MOLECULES WITH ANTISEIZURE EFFECTS DISCOVERED Nina Ottosson, principal research engineer at Linköping University. Credit: Thor Balkhed/ LiU A study will investigate whether it's possible to predict who remains susceptible to SARS-CoV-2 variants after having COVID-19 or receiving a COVID-19-specific vaccine THERAPEUTIC POTENTIAL OF MESENCHYMAL STROMAL CELLS BOOSTED Gel-coated (red) mesenchymal stromal cells (yellow) can degrade collagen (green) over a distance in the presence of tumor necrosis factor-alpha. Credit: Jae-Won Shin and Sing-Wan Wong/UIC Researchers have shown that a non-toxic complex of manganese makes it MOLECULAR MECHANISM OF IMMUNE CELL MIGRATION REVEALED (Left panel) Flow chart demonstrating dendritic cells (DCs) in wildtype (WT) and DC-specific Lamtor1-KO mice. In the absence of Lamtor1, skin-draining lymph nodes showed reduced numbers of migratory DCs. (Right panel) Representative images of the NEW STRATEGY FOR SELECTIVELY LABELING PEPTIDES Activation of a C-H bond at the end of the process of synthesis enables the fluorescent labelling of peptides and lipopeptides giving it properties that glow different colours. Credit: Nikolaos Kaplaneris/ University of Göttingen New research provides PRECISION SL HYDROGEN GENERATOR VIDEO Peak Scientific's Precision SL is the smallest hydrogen generator for GC-FID. The Precision SL line has been designed to offer a streamlined laboratory-grade hydrogen gas solution for GC flame detectors at a purity of 99.9995%, available in both 100 and 200cc/min. Precision issafe, simple to
UK’S PREFERENCE FOR ASTRAZENECA COVID-19 VACCINE HAS A new report by researchers including the University of Bristol and King's College London has found that the UK public's preference for the AstraZeneca–Oxford vaccine has declined since March. In March, the AstraZeneca–Oxford COVID-19 vaccine, Vaxzevria – formerly ChAdOx1 – was at the center of several regulatory agencyinvestigations
ACCELERATING DIAGNOSTIC TEST DEVELOPMENT INFOGRAPHIC Many clinical decisions are based on a diagnostic test, highlighting their importance in developing therapies and improving patient outcomes. There are many elements to consider when designing a diagnostic test, assay or kit, how to move from prototype to commercialization time efficiently may be one of the most important. DRUG SENSITIVITY OF LIVER CANCER CELLS Oncotarget published "Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells" which reported that this study aimed to investigate whether Hepatocellular Cancer (HCC) cells cultured in more native conditions have an altered phenotype and drug sensitivity compared to those cultured in standard conditions. STOPPING MATH EDUCATION EARLY IS BAD FOR THE BRAIN 1 day ago · Adolescents who stopped studying maths exhibited greater disadvantage - compared with peers who continued studying maths - in terms of brain and cognitive development, according to a new study published in the Proceedings of the National Academy of Sciences. 133 students between the ages of 14-18 took part in an experiment run by researchers from the Department of Experimental COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N proteinTECHNOLOGY NETWORKS
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research,videos and posters.
INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN Farming bacteria to produce hydrogen also has economic and environmental advantages – in the right setting, bacteria rapidly multiply, they are cheap to create and don’t need much space. The University team has used genetic engineering approaches to change the DNA of certain strains of E. coli bacteria to produce hydrogen fromsugars.
RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND The key differences between a paired and unpaired t-test are summarized below. A paired t-test is designed to compare the means of the same group or item under two separate scenarios. An unpaired t-test compares the means of two independent or unrelated groups. In an unpaired t-test, the variance between groups is assumed to beequal.
ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as money or food. "To the brain, information is its own reward, above and beyond whether it's useful," said Assoc. Prof. Ming Hsu, a neuroeconomist whose research employsfunctional
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
TECHNOLOGY NETWORKS
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research,videos and posters.
INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN Farming bacteria to produce hydrogen also has economic and environmental advantages – in the right setting, bacteria rapidly multiply, they are cheap to create and don’t need much space. The University team has used genetic engineering approaches to change the DNA of certain strains of E. coli bacteria to produce hydrogen fromsugars.
RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND The key differences between a paired and unpaired t-test are summarized below. A paired t-test is designed to compare the means of the same group or item under two separate scenarios. An unpaired t-test compares the means of two independent or unrelated groups. In an unpaired t-test, the variance between groups is assumed to beequal.
ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as money or food. "To the brain, information is its own reward, above and beyond whether it's useful," said Assoc. Prof. Ming Hsu, a neuroeconomist whose research employsfunctional
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
A SMALLER PILL LOADED WITH MORE DRUG MIT chemical engineers have devised a new way to formulate hydrophobic drugs by turning them into a nanoemulsion, which can be poured into a mold and dried into tablets. The nanoemulsion can also be used to form small particles, seen in the vials. Credit: Felice Frankel. The USFood and Drug
DRUG SENSITIVITY OF LIVER CANCER CELLS 8 hours ago · Oncotarget published "Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells" which reported that this study aimed to investigate whether Hepatocellular Cancer (HCC) cells cultured in more native conditions have an altered phenotype and drug sensitivity compared to those cultured in standardconditions.
NEW STRATEGY FOR SELECTIVELY LABELING PEPTIDES Activation of a C-H bond at the end of the process of synthesis enables the fluorescent labelling of peptides and lipopeptides giving it properties that glow different colours. Credit: Nikolaos Kaplaneris/ University of Göttingen New research provides MOLECULAR MECHANISM OF IMMUNE CELL MIGRATION REVEALED (Left panel) Flow chart demonstrating dendritic cells (DCs) in wildtype (WT) and DC-specific Lamtor1-KO mice. In the absence of Lamtor1, skin-draining lymph nodes showed reduced numbers of migratory DCs. (Right panel) Representative images of the CARBON NANOTUBE-BASED MATERIAL CAN POWER CHEMICAL 8 hours ago · MIT engineers have discovered a way to generate electricity using tiny carbon particles that can create an electric current simply by interacting with an organic solvent in which they’re floating. The particles are made from crushed carbon nanotubes (blue) coated with a Teflon-like polymer (green MOMS' SEIZURE MEDICATION NOT LINKED TO INFANT COGNITIVE If identical versions of 20 people lived out their lives in dozens of different worlds, would the same people be popular in each world? If you substitute "fruit flies" for "people" in that question, you have a fair description of a Rice University study showing that the evolutionof social
MOLECULE CRITICAL TO BRAIN REJUVENATION IDENTIFIED 8 hours ago · Recent studies suggest that new brain cells are being formed every day in response to injury, physical exercise, and mental stimulation. Glial cells, and in particular the ones called oligodendrocyte progenitors, are highly responsive to external signalsand injuries.
SARS-COV-2: EXPERIMENTAL ANTIVIRAL THERAPY COULD REDUCE An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome. MODERNA’S COVID-19 VACCINE IS SAFE AND EFFECTIVE IN TeenCOVE is the second clinical trial that has explored the safety and efficacy of mRNA-based COVID-19 vaccines in younger populations. Earlier in March, Pfizer–BioNTech announced that in a study of BNT162b2 in 12–15-year-olds, vaccine efficacy was calculated at 100%. Speaking of the latest results shared by Moderna, Russell Viner STOPPING MATH EDUCATION EARLY IS BAD FOR THE BRAIN 8 hours ago · Adolescents who stopped studying maths exhibited greater disadvantage - compared with peers who continued studying maths - in terms of brain and cognitive development, according to a new study published in the Proceedings of the National Academy of Sciences. 133 students between the ages of 14-18 took part in an experiment run by researchers from the Department of ExperimentalTECHNOLOGY NETWORKS
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research,videos and posters.
INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN Farming bacteria to produce hydrogen also has economic and environmental advantages – in the right setting, bacteria rapidly multiply, they are cheap to create and don’t need much space. The University team has used genetic engineering approaches to change the DNA of certain strains of E. coli bacteria to produce hydrogen fromsugars.
RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND The key differences between a paired and unpaired t-test are summarized below. A paired t-test is designed to compare the means of the same group or item under two separate scenarios. An unpaired t-test compares the means of two independent or unrelated groups. In an unpaired t-test, the variance between groups is assumed to beequal.
ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as money or food. "To the brain, information is its own reward, above and beyond whether it's useful," said Assoc. Prof. Ming Hsu, a neuroeconomist whose research employsfunctional
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
TECHNOLOGY NETWORKS
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research,videos and posters.
INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Methotrexate Users Respond Less Well to COVID-19 Vaccine. One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows. Published (online May 25) recently in Annals of the Rheumatic Diseases COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN Farming bacteria to produce hydrogen also has economic and environmental advantages – in the right setting, bacteria rapidly multiply, they are cheap to create and don’t need much space. The University team has used genetic engineering approaches to change the DNA of certain strains of E. coli bacteria to produce hydrogen fromsugars.
RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND The key differences between a paired and unpaired t-test are summarized below. A paired t-test is designed to compare the means of the same group or item under two separate scenarios. An unpaired t-test compares the means of two independent or unrelated groups. In an unpaired t-test, the variance between groups is assumed to beequal.
ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as money or food. "To the brain, information is its own reward, above and beyond whether it's useful," said Assoc. Prof. Ming Hsu, a neuroeconomist whose research employsfunctional
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
A SMALLER PILL LOADED WITH MORE DRUG MIT chemical engineers have devised a new way to formulate hydrophobic drugs by turning them into a nanoemulsion, which can be poured into a mold and dried into tablets. The nanoemulsion can also be used to form small particles, seen in the vials. Credit: Felice Frankel. The USFood and Drug
DRUG SENSITIVITY OF LIVER CANCER CELLS 4 hours ago · Oncotarget published "Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells" which reported that this study aimed to investigate whether Hepatocellular Cancer (HCC) cells cultured in more native conditions have an altered phenotype and drug sensitivity compared to those cultured in standardconditions.
NEW STRATEGY FOR SELECTIVELY LABELING PEPTIDES Activation of a C-H bond at the end of the process of synthesis enables the fluorescent labelling of peptides and lipopeptides giving it properties that glow different colours. Credit: Nikolaos Kaplaneris/ University of Göttingen New research provides MOLECULAR MECHANISM OF IMMUNE CELL MIGRATION REVEALED (Left panel) Flow chart demonstrating dendritic cells (DCs) in wildtype (WT) and DC-specific Lamtor1-KO mice. In the absence of Lamtor1, skin-draining lymph nodes showed reduced numbers of migratory DCs. (Right panel) Representative images of the CARBON NANOTUBE-BASED MATERIAL CAN POWER CHEMICAL 4 hours ago · MIT engineers have discovered a way to generate electricity using tiny carbon particles that can create an electric current simply by interacting with an organic solvent in which they’re floating. The particles are made from crushed carbon nanotubes (blue) coated with a Teflon-like polymer (green MOMS' SEIZURE MEDICATION NOT LINKED TO INFANT COGNITIVE If identical versions of 20 people lived out their lives in dozens of different worlds, would the same people be popular in each world? If you substitute "fruit flies" for "people" in that question, you have a fair description of a Rice University study showing that the evolutionof social
MOLECULE CRITICAL TO BRAIN REJUVENATION IDENTIFIED 4 hours ago · Recent studies suggest that new brain cells are being formed every day in response to injury, physical exercise, and mental stimulation. Glial cells, and in particular the ones called oligodendrocyte progenitors, are highly responsive to external signalsand injuries.
SARS-COV-2: EXPERIMENTAL ANTIVIRAL THERAPY COULD REDUCE An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome. MODERNA’S COVID-19 VACCINE IS SAFE AND EFFECTIVE IN TeenCOVE is the second clinical trial that has explored the safety and efficacy of mRNA-based COVID-19 vaccines in younger populations. Earlier in March, Pfizer–BioNTech announced that in a study of BNT162b2 in 12–15-year-olds, vaccine efficacy was calculated at 100%. Speaking of the latest results shared by Moderna, Russell Viner STOPPING MATH EDUCATION EARLY IS BAD FOR THE BRAIN 5 hours ago · Adolescents who stopped studying maths exhibited greater disadvantage - compared with peers who continued studying maths - in terms of brain and cognitive development, according to a new study published in the Proceedings of the National Academy of Sciences. 133 students between the ages of 14-18 took part in an experiment run by researchers from the Department of ExperimentalTECHNOLOGY NETWORKS
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INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Two new studies in mice suggest that the double-edged nature of the relationship between the immune system and the brain may come down to the origins of the immune cells that patrol the meninges, the tissues that surround the brain and spinal cord. Researchers have discovered that cepharanthine and COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN A genetically-engineered sugar-loving bacteria has been created that can produce on-demand, zero-emission hydrogen fuel faster than has been done anywhere else. RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND This article will explain when it is appropriate to use a paired t-test versus an unpaired t-test, as well as the hypothesis and assumptions of each. ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK Can't stop checking your phone, even when you're not expecting any important messages? Blame your brain. A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as moneyor food.
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
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Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research,videos and posters.
INDIVIDUALS TAKING METHOTREXATE RESPOND LESS WELL TO COVID Two new studies in mice suggest that the double-edged nature of the relationship between the immune system and the brain may come down to the origins of the immune cells that patrol the meninges, the tissues that surround the brain and spinal cord. Researchers have discovered that cepharanthine and COVID-19 ANTIBODY TESTING: S VS. N PROTEIN Technology Networks spoke to Dr Iswariya Venkataraman, Scientific Affairs Lead at EUROIMMUN US, to learn about the differences between the S and N proteins and what makes them suitable as target antigens in serology testing. Iswariya also discussed the findings and implications from a study which cautioned against the extensive use of tests that detect antibodies against the N protein BACTERIA COULD PROVIDE CHEAP, CLEAN HYDROGEN A genetically-engineered sugar-loving bacteria has been created that can produce on-demand, zero-emission hydrogen fuel faster than has been done anywhere else. RADIOCARBON DATING ACCURACY SET TO IMPROVE Scientists have used measurements from almost 15,000 samples from objects dating back as far as 60,000 years ago, as part of a seven-year project to create new international radiocarbon calibration curves, key for archaeology and environmental science. HOW CAN THE INTERNET OF THINGS IMPROVE LAB RESEARCHHOW IMPROVE INTERNET SPEEDHOW TO DO INTERNET RESEARCHHOW TO IMPROVE HOME INTERNETHOW TO IMPROVE INTERNET STABILITYHOW TO IMPROVE YOUR INTERNETUSING THE INTERNET FOR RESEARCH The internet of things (IoT) has been used in hospitals to track people, supplies and equipment so that they can improve workflow, reduce congestion and delays, monitor the condition of equipment and reduce the misplacement of devices. Will it PAIRED VS UNPAIRED T-TEST: DIFFERENCES, ASSUMPTIONS AND This article will explain when it is appropriate to use a paired t-test versus an unpaired t-test, as well as the hypothesis and assumptions of each. ONE-WAY VS TWO-WAY ANOVA: DIFFERENCES, ASSUMPTIONS AND A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test. YOUR BRAIN GETS A DOPAMINE HIT FROM INFORMATIONHOW DOES DOPAMINE WORK Can't stop checking your phone, even when you're not expecting any important messages? Blame your brain. A new study by researchers at UC Berkeley's Haas School of Business has found that information acts on the brain's dopamine-producing reward system in the same way as moneyor food.
ACTIVE VS PASSIVE IMMUNITY: DIFFERENCES AND DEFINITION Immunity is defined as the body’s ability to protect itself from an infectious disease. When you are immune to a disease, your immune system can fight off infection from it. In this article, we compare and contrast two types of acquired immunity: active and passiveimmunity.
COVID-19: GENE FOUND THREE TIMES AS OFTEN IN PEOPLE WHO The first evidence of a genetic link explaining why some people who catch Covid-19 don't become sick has been discovered. A scientific and medical team led by Newcastle University, UK, has demonstrated that the gene, HLA-DRB1*04:01, is found three SARS-COV-2: EXPERIMENTAL ANTIVIRAL THERAPY COULD REDUCE An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome. FDA CONTROVERSIALLY APPROVES ALZHEIMER'S DRUG ADUCANUMAB 9 hours ago · The US Food and Drug Administration today (June 7) announced the results of their investigation into Biogen’s investigational treatment for Alzheimer’s disease (AD), the monoclonal antibody aducanumab. The agency announced that the compound, under the trade name Aduhelm, is to be approved for treatment, via the FDA’s accelerated approval pathway. MODERNA’S COVID-19 VACCINE IS SAFE AND EFFECTIVE IN Moderna has announced that a Phase II/III clinical trial, known as TeenCOVE, of its COVID-19 vaccine (mRNA-1273) in adolescents has met its primary immunogenicity endpoint.The public statement is not accompanied by data at this stage, but the biotechnology company said that it plans to submit the findings to a peer-reviewed journal forpublication.
REVEALING THE MICROSCOPIC WORLD BENEATH OUR FEET Boston University researchers develop first-of-its-kind model to predict which species of soil organisms live in different environments, with huge implications for agriculture, climate change, and public health. Credit: Florian van Duyn on Unsplash. A first encounter with the dengue virus typically PROTEIN ISOFORM EXPRESSION CAN NOW BE FOLLOWED IN LIVE Self-excising designer proteins report isoform expression. Credit: Barth van Rossum Researchers have demonstrated a base editing approach that corrects the mutation underlying sickle cell disease in patient blood stem cells. As meat-eating continues to COMPUTER SIMULATIONS OF THE BRAIN PREDICT STROKE RECOVERY At Boston University, a team of researchers is working to better understand how language and speech is processed in the brain, and how to best rehabilitate people who have lost their ability to communicate due to brain damage caused by a stroke, trauma, or another type ofbrain injury.
BOWEL CANCER RECURRENCE COULD BE PREDICTED BY BLOOD A biomarker in the blood of patients with bowel cancer may provide valuable insight into the risk of cancer relapse after surgery and the effectiveness of chemotherapy. BABIES' EXPERIENCE OF FEAR LINKED TO GUT BACTERIA 16 hours ago · How old is your brain compared to your chronological age? A new measure of brain health developed may offer a novel approach to identifying individuals at risk of memory and thinking problems. Scientists have developed a first-of-its-kind model to predict which species of soil organisms live in USING LED LIGHT FROM A SMARTWATCH TO CONTROL INSULIN Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer's heart rate during physical activity or while at rest.__
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MAPPING THE HUMAN PROTEOME: A JOURNEYArticle
In 2020, we celebrate 90% of the human proteome being mapped by the Human Proteome Project (HPP). In this article, we reflect on the history of this endeavor and the future of the proteomics field, speaking with individuals close to the project.Read more __
RESEARCHERS TRACE THE SPREAD OF SARS-COV-2 FROM NOSE TO BRAINNews
A study has found that the coronavirus SARS-CoV-2, the cause of the COVID-19 pandemic, may be able to access the brain by spreading through the border between our nasal system and neural tissue.Read more __
MYTHS ABOUT IP - PRE-CLEARING IS NECESSARY TO GET GOOD RESULTSVideo
Is it really necessary to pre-clear your sample prior to immunoprecipitation? Watch the video and learn how you can avoid background without any pre-clearing.Watch Now __
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VALIDATING HYDRATION ASSESSMENT TOOLS FOR AN ATHLETIC POPULATION: AN EFFORT TO PREVENT DEHYDRATIONArticle
Dehydration is a well-documented hindrance to athletic performance. Staying properly hydrated for event days and during training is therefore of utmost importance. Scientists have therefore been looking at ways to enhance and optimize athlete hydration.Read more __
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DRUG REVERSES AGE-RELATED MENTAL DECLINE WITHIN DAYS IN MOUSE MODELNews
An experimental drug called ISRIB has been shown to reverse age-related declines in memory and mental flexibility in mice.Read more __
WHAT EFFECT DOES SOCIAL DISTANCING HAVE ON THE BRAIN?News
A new molecule has been discovered in the brain of animals, that acts as a 'thermometer' to feel others' presence.Read more __
------------------------- EXPLORING BACTERIA'S METABOLISM TO IMPROVE BIOFUEL PRODUCTIONNews
News research has shown how bacteria produce chemicals dependant on the food that is ingested.Read more __
------------------------- CO-MUTATION POINTS TO NEW TARGET FOR AGGRESSIVE FORM OF LUNG CANCERNews
A team of researchers has identified two gene mutations found in aggressive lung adenocarcinomas.Read more __
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Articles View All __ REGULATING HEAVY METALS IN CANNABIS: WHAT CAN BE LEARNED FROM THE PHARMACEUTICAL INDUSTRY? PART 1Article
This article is the first part in a series on the importance of measuring heavy metals in cannabis and hemp. In particular, the series will explore how the cannabis industry can learn a great deal from the pharmaceutical industry, which took over 20 years to bring in meaningful and comprehensive regulations for elemental impurities to ensure the safety and efficacy of drug products.Read more __
------------------------- SNIFFING OUT NEW METHODS FOR IN-FIELD PESTICIDE DETECTIONArticle
This article addresses the issues associated with the global use of pesticides, and some ways in which these can be overcome.Read more __
------------------------- DIVERSE OPINIONS TO COMMON CHALLENGES IN THE FIELD OF METABOLOMICSArticle
The diverse nature of the metabolome continually challenges researchers and creates a colorful array of opinions on which is the most comprehensive and precise approach, explored in this article.Read more __
------------------------- MAPPING THE HUMAN PROTEOME: A CONVERSATION WITH PROFESSOR EMANUELPETRICOIN
Article
This year, science celebrates mapping 90% of the human proteome, an endeavor that has been achieved by the Human Proteome Project (HPP). _Technology Networks_ explored the journey to this successful feat by speaking with Professor Emanuel Petricoin.Read more __
------------------------- MAPPING THE HUMAN PROTEOME: A CONVERSATION WITH DR LYDIE LANEArticle
This year, science celebrates mapping 90% of the human proteome, an endeavor that has been achieved by the Human Proteome Project (HPP). _Technology Networks_ explored the journey to this successful feat by speaking with Dr Lydie Lane.Read more __
------------------------- MAPPING THE HUMAN PROTEOME: A CONVERSATION WITH PROFESSOR CHRISOVERALL
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This year, science celebrates mapping 90% of the human proteome, an endeavor that has been achieved by the Human Proteome Project (HPP). _Technology Networks_ spoke with Professor Chris Overall, Chair of the C-HPP, to learn more.Read more __
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In association with LabTube __ TEACH ME IN 10 – WHY COVID-19 GENETICS RESEARCH MAY BE BIASED WITH DR THOMAS STOEGERVideo
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Webinars View All __ NATIVE MASS SPECTROMETRY AND COVID-19: UNCOVERING DRUG BINDING ANDOLIGOMERIZATION
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------------------------- HACKS, DISASTERS AND COVID-19: HOW TO KEEP YOUR LAB RUNNINGWebinar
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------------------------- THE SCIENCE OF CANNABIS CULTIVATION 2020Webinar
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------------------------- View All Webinars __ Infographics & Lists HOW MODERN GENOMICS IS REWRITING OUR UNDERSTANDING OF HISTORYListicle
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------------------------- STEPS TO CONSIDER WHEN SELECTING A CHROMATOGRAPHY DATA SYSTEMListicle
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PLENARENO PHARMA MIDDLE EAST CONGRESSEvent
__Â Dec 07 - Dec 08, 2020__ Abu Dhabi, UAE
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------------------------- PRE-FILLED SYRINGES AND INJECTABLE DRUG DEVICES 2021Event
__Â Jan 13 - Jan 14, 2021 __ Scarsdale Pl, Kensington, London W8 5SY London, UKRead More __
------------------------- 2ND EUROPEAN GYNECOLOGY AND OBSTETRICS CONGRESSEvent
__Â Feb 15 - Feb 16, 2021__ Paris, France
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