SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NEWS – PAGE 117 – SPEAKING OF RESEARCH On the University of Florida campus, the animal rights movement has been rekindled. On a weekend in early July, Lisa Grossman and Camille Marino, self-proclaimed animal extremists and members of the group Negotiation Is Over (NIO), were seen handing out fliers offering $100 for the personal information of students who conduct research on

animals (see

PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in THE UK IS HOPING TO PASS AN ANIMAL SENTIENCE BILL. AGAIN The Conservatives, who both historically struggled with a reputation of being the ‘nasty party’ (this is ‘nasty’ by the UK definition by the way) and were also keen to show that leaving the EU was a good idea claimed that, free from the EU, the UK would be free to go ‘even further’ to protect animal sentience than a mere

clause in a treaty.

WHY NONHUMAN PRIMATES ARE ESSENTIAL FOR ADDRESSING May 20th 2021Agnès Lacreuse, PhD Our world is aging at an unprecedented rate. The number of older people is projected to double every 20 years, and reach about 17% of the total population by 2050. These figures are alarming, as age is the primary risk factor for developing devastating diseases such as Alzheimer’s disease (AD). EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

EDITOR – PAGE 11 – SPEAKING OF RESEARCH by Juan Carlos Marvizon, Ph.D., Adjunct Professor, UCLA Many of my scientists colleagues are thrilled about these new techniques. They represent the convergence of decades of work in areas as diverse as molecular biology, protein chemistry, cellular biology, neuroscience, microbiology, virology UNDERSTANDING ADVERSE DRUG REACTIONS (ADRS) Recent Posts. FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed with monkeys could change that May 25, 2021; Call for scientific journals to adopt accurate language about the sex of nonhuman animals May 21, 2021 FROM MOUSE TO MONKEY TO HUMANS: THE STORY OF RITUXIMAB Rituximab is an interesting drug, as it is a chimeric antibody. This means that it contains portions of both human and mouse antibodies mixed together. The first papers reporting on rituximab were published in 1994. The first looked at its creation, and the second reported on the phase I clinical trials of the drug. SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in NEWS – PAGE 116 – SPEAKING OF RESEARCH Posts about News written by Editor and darioringach. We recently updated the statistics page of the website. Here are the highlights: The numbers of dogs used in research was at its lowest rate since measurements began in the 1970s. WHY NONHUMAN PRIMATES ARE ESSENTIAL FOR ADDRESSING May 20th 2021Agnès Lacreuse, PhD Our world is aging at an unprecedented rate. The number of older people is projected to double every 20 years, and reach about 17% of the total population by 2050. These figures are alarming, as age is the primary risk factor for developing devastating diseases such as Alzheimer’s disease (AD). EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

THE UK IS HOPING TO PASS AN ANIMAL SENTIENCE BILL. AGAIN The Conservatives, who both historically struggled with a reputation of being the ‘nasty party’ (this is ‘nasty’ by the UK definition by the way) and were also keen to show that leaving the EU was a good idea claimed that, free from the EU, the UK would be free to go ‘even further’ to protect animal sentience than a mere

clause in a treaty.

FROM MOUSE TO MONKEY TO HUMANS: THE STORY OF RITUXIMAB Rituximab is an interesting drug, as it is a chimeric antibody. This means that it contains portions of both human and mouse antibodies mixed together. The first papers reporting on rituximab were published in 1994. The first looked at its creation, and the second reported on the phase I clinical trials of the drug. SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary ANIMAL RESEARCH REGULATIONS IN THE EU EU Directive 2010/63 is the regulation guiding the protection of animals used for scientific purposes in EU member states. Below we outline some of the key aspects of the regulation. Overview Licences and Approval Suffering 3Rs: Replacement, Refinement and Reduction of animals in research Species specific regulation regulations Other regulations and limitations Overview Countries in NEWS – PAGE 116 – SPEAKING OF RESEARCH Posts about News written by Editor and darioringach. We recently updated the statistics page of the website. Here are the highlights: The numbers of dogs used in research was at its lowest rate since measurements began in the 1970s. WHY NONHUMAN PRIMATES ARE ESSENTIAL FOR ADDRESSING May 20th 2021Agnès Lacreuse, PhD Our world is aging at an unprecedented rate. The number of older people is projected to double every 20 years, and reach about 17% of the total population by 2050. These figures are alarming, as age is the primary risk factor for developing devastating diseases such as Alzheimer’s disease (AD). EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

THE UK IS HOPING TO PASS AN ANIMAL SENTIENCE BILL. AGAIN The Conservatives, who both historically struggled with a reputation of being the ‘nasty party’ (this is ‘nasty’ by the UK definition by the way) and were also keen to show that leaving the EU was a good idea claimed that, free from the EU, the UK would be free to go ‘even further’ to protect animal sentience than a mere

clause in a treaty.

FROM MOUSE TO MONKEY TO HUMANS: THE STORY OF RITUXIMAB Rituximab is an interesting drug, as it is a chimeric antibody. This means that it contains portions of both human and mouse antibodies mixed together. The first papers reporting on rituximab were published in 1994. The first looked at its creation, and the second reported on the phase I clinical trials of the drug. SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH Arguments For Animal Research. While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

WHERE DO PETA’S DONATION DOLLARS GO? It’s common for charities to ask donors to exercise their giving spirit during the holidays. People for the Ethical Treatment of Animals (PETA) sure does. They join several other nonprofits in asking supporters to give heavily and often as we transition from one year to another. Andit works: PETA’s 2010 donations totaled $33 million ($35 SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH Arguments For Animal Research. While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

WHERE DO PETA’S DONATION DOLLARS GO? It’s common for charities to ask donors to exercise their giving spirit during the holidays. People for the Ethical Treatment of Animals (PETA) sure does. They join several other nonprofits in asking supporters to give heavily and often as we transition from one year to another. Andit works: PETA’s 2010 donations totaled $33 million ($35

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed WORLDWIDE ANIMAL RESEARCH STATISTICS While animal research is conducted in most countries in the world, it is hard to come up with any accurate worldwide figures. Below we track the official statistics produced by countries, however, there are differences in the way these figures are recorded and reported. EU countries count animal experiments, while most other countries count

the number

THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a NEWS – PAGE 116 – SPEAKING OF RESEARCH Posts about News written by Editor and darioringach. We recently updated the statistics page of the website. Here are the highlights: The numbers of dogs used in research was at its lowest rate since measurements began in the 1970s. EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

ANIMAL RESEARCH REGULATIONS IN THE US Regulatory Requirements The Institutional Official Institutional Animal Care and Use Committee (IACUC) The Attending Veterinarian Regulatory Requirements Research with animals is guided by a complex set of federal and state laws, regulations, and guidelines, and by additional institutional policies implemented to systematically address federal requirements and as the result of a voluntary ANIMAL WELFARE AND THE 3RS The 3Rs: Replacement, Reduction, and Refinement, are important from a legal, ethical and scientific standpoint. All research using animals in the US, for example at universities and pharmaceutical companies, is regulated by the Animal Welfare Act (AWA), which is administered by the Animal and Plant Health Inspection Service (APHIS) of the US Department of Agriculture

24 HOURS A DAY

24 hours a day – 7 days a week – 365 days a year. 21st February 2020. Kelsey Finnie, DVM. While scientists, research staff, husbandry technicians, and others work very hard to ensure laboratory animals are well-cared for, those animals involved in research and teaching, also have access to specialized veterinarians and veterinary care 24 ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed

JUNE 3, 2021

June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most

MAY 27, 2021

2 posts published by Editor on May 27, 2021. May 27th 2021 While much has been written about the various COVID-19 vaccines (prevention), including here are Speaking of Research, less emphasis has been placed on the treatment of COVID-19 patients—both earlier on THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and NEWS – PAGE 116 – SPEAKING OF RESEARCH Posts about News written by Editor and darioringach. We recently updated the statistics page of the website. Here are the highlights: The numbers of dogs used in research was at its lowest rate since measurements began in the 1970s. EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a

OF WHAT USE?

By Isaac Asimov One may detest nature and despise science, but it becomes more and more difficult to ignore them. Science in the modern world is not an entertainment for some devotees. It is on its way to becoming every-body's business. -- Theodosius Dobzhansky, in The Biology of Ultimate Concern. It is the fate of THE UK IS HOPING TO PASS AN ANIMAL SENTIENCE BILL. AGAIN The Conservatives, who both historically struggled with a reputation of being the ‘nasty party’ (this is ‘nasty’ by the UK definition by the way) and were also keen to show that leaving the EU was a good idea claimed that, free from the EU, the UK would be free to go ‘even further’ to protect animal sentience than a mere

clause in a treaty.

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

NIH DIRECTOR DR. FRANCIS COLLINS SPEAKS TRUTH TO POWER May 27, 2021 On Tuesday, NIH Director Dr. Francis Collins and NIAID Director Dr. Anthony Fauci testified before the House Appropriations Committee (Rep. Rosa DeLauro, D-CT, Chair). Their testimony addressed questions on the fiscal year 2022 budget request for the NIH. This process occurs each year. (Watch the full hearing here). If we’re

going to

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed

JUNE 3, 2021

June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most

MAY 27, 2021

2 posts published by Editor on May 27, 2021. May 27th 2021 While much has been written about the various COVID-19 vaccines (prevention), including here are Speaking of Research, less emphasis has been placed on the treatment of COVID-19 patients—both earlier on THE #ANIMALRESEARCH BEHIND THE 2021 BRAIN PRIZE The #AnimalResearch behind the 2021 Brain Prize. The Lundbeck Foundation in Denmark announced on Thursday that the British researcher Peter Goadsby, Michael Moskowitz of the US, Lars Edvinsson of Sweden and Jes Olesen of Denmark had won the ~1.6 Million US dollar Brain prize. Their research delineated the neural basis of migraine, a NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and NEWS – PAGE 116 – SPEAKING OF RESEARCH Posts about News written by Editor and darioringach. We recently updated the statistics page of the website. Here are the highlights: The numbers of dogs used in research was at its lowest rate since measurements began in the 1970s. EDITOR – PAGE 10 – SPEAKING OF RESEARCH Read all of the posts by Editor on Speaking of Research. Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each

week.

COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a

OF WHAT USE?

By Isaac Asimov One may detest nature and despise science, but it becomes more and more difficult to ignore them. Science in the modern world is not an entertainment for some devotees. It is on its way to becoming every-body's business. -- Theodosius Dobzhansky, in The Biology of Ultimate Concern. It is the fate of THE UK IS HOPING TO PASS AN ANIMAL SENTIENCE BILL. AGAIN The Conservatives, who both historically struggled with a reputation of being the ‘nasty party’ (this is ‘nasty’ by the UK definition by the way) and were also keen to show that leaving the EU was a good idea claimed that, free from the EU, the UK would be free to go ‘even further’ to protect animal sentience than a mere

clause in a treaty.

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

JUNE 3, 2021

Recent Posts. FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed with monkeys could change that May 25, 2021; Call for scientific journals to adopt accurate

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed FDA APPROVES LUNG CANCER DRUG #MPAR June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most common PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH Arguments For Animal Research. While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below

24 HOURS A DAY

24 hours a day – 7 days a week – 365 days a year. 21st February 2020. Kelsey Finnie, DVM. While scientists, research staff, husbandry technicians, and others work very hard to ensure laboratory animals are well-cared for, those animals involved in research and teaching, also have access to specialized veterinarians and veterinary care 24

BEING HUMANE

There are differences. Humans can transcend their biological lives in ways that other animals cannot. Humans can study, understand and challenge nature by means of technological might, in ways other animals cannot. Humans can store knowledge in perpetual form and secure its benefits for all future generations, in ways other animals

cannot.

ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

JUNE 3, 2021

Recent Posts. FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed with monkeys could change that May 25, 2021; Call for scientific journals to adopt accurate

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed FDA APPROVES LUNG CANCER DRUG #MPAR June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most common PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH Arguments For Animal Research. While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below

24 HOURS A DAY

24 hours a day – 7 days a week – 365 days a year. 21st February 2020. Kelsey Finnie, DVM. While scientists, research staff, husbandry technicians, and others work very hard to ensure laboratory animals are well-cared for, those animals involved in research and teaching, also have access to specialized veterinarians and veterinary care 24

BEING HUMANE

There are differences. Humans can transcend their biological lives in ways that other animals cannot. Humans can study, understand and challenge nature by means of technological might, in ways other animals cannot. Humans can store knowledge in perpetual form and secure its benefits for all future generations, in ways other animals

cannot.

ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

SPEAKING OF RESEARCH Speaking of Research – Improving understanding about Animal Research / Animal Testing. Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences. Mice, rats and fish account for around 95% of animals used in

experiments.

ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR One step closer to treating spinal cord injury with our own stem cells. March 15th 2021. Justin Varholick, PhD. Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to

walk and use

INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test. BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, ANDANIMAL RESEARCH PROJECTEXAMPLES OF ANIMAL RESEARCHFUTURE RESEARCH CORPORATIONFUTURE RESEARCH IDEASFUTURE RESEARCH INCHISTORY OF ANIMAL RESEARCH January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

OF WHAT USE?

There is a famous story of a student who asked the Greek philosopher Plato, about 370 B.C., of what use were the elaborate and abstract theorems he was being taught. Plato at once ordered a slave to give the student a small coin that he might not think he had gained knowledge for nothing, then had him dismissed from the school. EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

JUNE 3, 2021

Recent Posts. FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed with monkeys could change that May 25, 2021; Call for scientific journals to adopt accurate

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed FDA APPROVES LUNG CANCER DRUG #MPAR June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most common PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH Arguments For Animal Research. While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below

24 HOURS A DAY

24 hours a day – 7 days a week – 365 days a year. 21st February 2020. Kelsey Finnie, DVM. While scientists, research staff, husbandry technicians, and others work very hard to ensure laboratory animals are well-cared for, those animals involved in research and teaching, also have access to specialized veterinarians and veterinary care 24

BEING HUMANE

There are differences. Humans can transcend their biological lives in ways that other animals cannot. Humans can study, understand and challenge nature by means of technological might, in ways other animals cannot. Humans can store knowledge in perpetual form and secure its benefits for all future generations, in ways other animals

cannot.

ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and SPEAKING OF RESEARCH Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences.. Mice, rats and fish account for around 95% of animals used in experiments ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR March 15th 2021 Justin Varholick, PhD Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to walk and use their hands. Previous to the treatment, 13 patients had sustained

falls or minor

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test.

OF WHAT USE?

By Isaac Asimov One may detest nature and despise science, but it becomes more and more difficult to ignore them. Science in the modern world is not an entertainment for some devotees. It is on its way to becoming every-body's business. -- Theodosius Dobzhansky, in The Biology of Ultimate Concern. It is the fate of DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

ZERHOUNI SETS THE RECORD STRAIGHT ON ANIMAL RESEARCH On June 4th 2013, Elias Zerhouni, a former Director of the National Institutes of Health (NIH) made some comments at a Scientific Management and Review Board (SMRB) meeting that were reported in NIH Record as follows: “We have moved away from studying human disease in humans,” he lamented. “We all drank the Kool-Aid on that SPEAKING OF RESEARCH Speaking of Research is an international advocacy group that provides accurate information about the importance of animal research in the biomedical, behavioral, and life sciences.. Mice, rats and fish account for around 95% of animals used in experiments ONE STEP CLOSER TO TREATING SPINAL CORD INJURY WITH OUR March 15th 2021 Justin Varholick, PhD Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to walk and use their hands. Previous to the treatment, 13 patients had sustained

falls or minor

BREAKTHROUGH: HER VISION WAS GETTING WORSE, THEN ANIMAL By Justin A. Varholick, Ph.D. As we grow older there’s an impending fear that we will slowly, but surely, begin to lose our vision. This slow loss of vision is clinically dubbed ‘low vision’ and impacts more than 39 million Americans, costs $68 billion annually in INTERVIEW – SPEAKING OF RESEARCH It's been over a week since our last coverage update and there's been more news sources covering the upcoming rally. To kick off, the highly respected Nature journal included an interview (subscription needed) with David Jentsch, founder of UCLA Pro-Test.

OF WHAT USE?

By Isaac Asimov One may detest nature and despise science, but it becomes more and more difficult to ignore them. Science in the modern world is not an entertainment for some devotees. It is on its way to becoming every-body's business. -- Theodosius Dobzhansky, in The Biology of Ultimate Concern. It is the fate of DEBUNKING THE ABSURD “TAXPAYER WASTE” ARGUMENT In recent years, animal rights activists have shifted their tactics aimed at convincing Americans to reject animal-based research, despite its tremendous benefits. We’ve witnessed an increase in lobbying and activist-inspired legislation, especially at the state and local levels. Furthermore, we’re happy to report that extremist acts are

on the decline.

EMPATHY AND ALTRUISM IN RATS? A recent paper in Science discussed behavioral data in rats suggestive of empathically motivated behavior. This is a potentially very important report for two major reasons. First, a deep understanding of the mental and psychological abilities of rats, and other species, is a crucial goal for comparative psychologists, evolutionary biologists and other basic scientists. CLINICAL TRIAL SUCCESS FOR CYSTIC FIBROSIS GENE THERAPYCYSTIC FIBROSIS GENE THERAPY WORKTESTING FOR CYSTIC FIBROSIS GENECYSTIC FIBROSIS GENE CARRIERGENE FOR CYSTIC FIBROSISCYSTIC FIBROSIS GENE MUTATION TYPESCYSTIC FIBROSIS NEW THERAPY This morning the Cystic Fibrosis Gene Therapy Consortium (GTC) announced the results of clinical trial in 140 patients with cystic fibrosis, which demonstrate the potential for gene therapy to slow – and potentially halt - the decline of lung function in people with the

disorder. It

CAN CELL LINES REPLACE ANIMAL RESEARCH Teresa Romeo Luperchio is a graduate student at The Johns Hopkins University School of Medicine and is currently working as a FASEB Office of Public Affairs Fellow. In this post Teresa tackles the difficult question of why cell lines could not replace all animal studies. A common theme in alternatives to animal testing is that

tissue

ZERHOUNI SETS THE RECORD STRAIGHT ON ANIMAL RESEARCH On June 4th 2013, Elias Zerhouni, a former Director of the National Institutes of Health (NIH) made some comments at a Scientific Management and Review Board (SMRB) meeting that were reported in NIH Record as follows: “We have moved away from studying human disease in humans,” he lamented. “We all drank the Kool-Aid on that

JUNE 3, 2021

Recent Posts. FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed with monkeys could change that May 25, 2021; Call for scientific journals to adopt accurate

JUNE 4, 2021

Recent Posts. Puberty blockers are all over the news (and laws). How did they come about? June 4, 2021; FDA approves lung cancer drug #MPAR June 3, 2021; FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 May 27, 2021; NIH Director Dr. Francis Collins Speaks Truth to Power May 27, 2021; The pandemic isn’t over, but a new pan-coronavirus vaccine developed FDA APPROVES LUNG CANCER DRUG #MPAR June 3rd 2021 Recently, the FDA approved an Amgen drug, sotorasib, for non-small cell lung cancer (NSCLS) with a specific mutation in a gene known as Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients whose disease has worsened after treatment with chemotherapy or other medicines. This mutation accounts for 13% of NSCLS—the most common PUBERTY BLOCKERS ARE ALL OVER THE NEWS (AND LAWS). HOW DID Puberty blockers are not permanent. The drugs, gonadotropin releasing hormone or GnRH analogues, act by temporarily suppressing the body’s release of sex hormones, including testosterone and estrogen, during puberty.As a result, there is a temporary COMPUTER MODELS ARE NOT REPLACING ANIMAL RESEARCH, AND January 7th 2020 Juan Carlos Marvizon, Ph.D. David Geffen School of Medicine at UCLA, VA Greater Los Angeles The buzz is everywhere when animal research is mentioned: experiments in animals are outdated because computer models and other modern techniques are replacing them. For example, you may have heard statements like these: “Researchers have developed a ARGUMENTS FOR ANIMAL RESEARCH While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter – which is why each of our lines below includes a “Tweet This” option.

24 HOURS A DAY

21st February 2020 Kelsey Finnie, DVM While scientists, research staff, husbandry technicians, and others work very hard to ensure laboratory animals are well-cared for, those animals involved in research and teaching, also have access to specialized veterinarians and veterinary care 24 hours a day - 7 days a week - 365 days a year.

But what

BEING HUMANE

There are differences. Humans can transcend their biological lives in ways that other animals cannot. Humans can study, understand and challenge nature by means of technological might, in ways other animals cannot. Humans can store knowledge in perpetual form and secure its benefits for all future generations, in ways other animals

cannot.

ANIMAL TESTING AND HUMAN TRIALS: ALTERNATIVES OR The Animal Justice Project, a British-based animal rights group, is no stranger to misinformation. Previously we have debunked their factual errors regarding malaria studies in Sweden and eye injury studies. There was also the time they produced a press release which suggested 52oC (125oF) was the same as boiling water (which admittedly might be

true

NEWS – PAGE 115 – SPEAKING OF RESEARCH The status and future of chimpanzee research in the US are at the heart of much discussion lately in both scientific and public spheres. Discussion of human relationships with the great apes, their role in research—past, present, and future—and our responsibility for their continued care deserve thoughtful, well-informed consideration by both the scientific community and

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