BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

No special requirement - Use standard laboratory instrument, Luminex is not needed. Works with Mammalian Nuclear Extracts- Samples can be taken from human, mouse, or rat and more. Product Name. Catalog #. Price. Qty. TF Activation Profiling Plate Array I. FA-1001. $583. SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

No special requirement - Use standard laboratory instrument, Luminex is not needed. Works with Mammalian Nuclear Extracts- Samples can be taken from human, mouse, or rat and more. Product Name. Catalog #. Price. Qty. TF Activation Profiling Plate Array I. FA-1001. $583. SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

SIGNOSIS

Signosis, Inc. 1700 Wyatt Drive, Suite # 10-12 Santa Clara, CA 95054

USA

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

HER2 (ERBB2) Stably Expressing Cell Lines. The proto-oncogene human epidermal growth factor receptor 2 (HER2) gene also known as ERBB2 is a member of the ERBB/HER RTK family which comprised of EGFR (EGFR/HER1/ERBB1), HER3/ERBB3 and HER4/ERBB4. This gene encodes for a transmembrane glycoprotein receptor with an intracellular domain with tyrosine kinase activity which is responsible for

SIGNOSIS

The GAL4-UAS system is a powerful technique for studying gene expression and function. It has also been adapted to study nuclear receptor chemical-binding functions. Signosis GAL4-UAS-luc Reporter Stable Cell Lines is a reliable, rapid, and sensitive method for analyzing the expression of your target gene upon exposure to related

ligands or

SIGNOSIS

Inflammation is the response of tissue to injury. During both acute and chronic inflammatory processes, a variety of soluble factors are involved in the cellular infiltrate, the cellular activation, and the systemic responses to inflammation. Cytokines are major determinants of inflammatory responses. Most cytokines are multifunctional

SIGNOSIS

Signosis has developed NRF2-reporter MCF7 stable cell line that has been stably transfected with pTA-NRF2-luciferase reporter vector, which contains 8 repeats of NRF2 binding sites, a minimal promoter upstream of the firefly luciferase coding region, along with a G418 expression vector. This cell line can be used to investigate oxidative

stress

SIGNOSIS

Product Name Catalog # Price Qty; p53 Snapshot Microplate ChIP Assay strips: CP-0110S: $232-+

SIGNOSIS

Cytokines that are secreted from cells bind to cell-surface receptors, initiate the activation of signal transduction pathways and mediate cell to cell communication. The malfunction of cytokines leads to many diseases, including arthritis, acute and chronic liver disease, inflammatory bowel disease, cardiac-related diseases, and cancers.

SIGNOSIS

Principle. The GAL4-UAS system is a powerful technique for studying of gene expression in some model organisms such as Drosophila. It can also be adapted to study

SIGNOSIS

Signosis has established NFAT luciferase reporter Jurkat T cell line that has been stably transfected with a NFAT-luciferase reporter construct. Via the analysis of luciferase, the cell line can be employed to monitor the cellular changes of NFAT activities that are triggered by stimulation, compound treatment, enforced gene expression

or gene

BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

No special requirement - Use standard laboratory instrument, Luminex is not needed. Works with Mammalian Nuclear Extracts- Samples can be taken from human, mouse, or rat and more. Product Name. Catalog #. Price. Qty. TF Activation Profiling Plate Array I. FA-1001. $583. SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

No special requirement - Use standard laboratory instrument, Luminex is not needed. Works with Mammalian Nuclear Extracts- Samples can be taken from human, mouse, or rat and more. Product Name. Catalog #. Price. Qty. TF Activation Profiling Plate Array I. FA-1001. $583. SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

SIGNOSIS

Signosis, Inc. 1700 Wyatt Drive, Suite # 10-12 Santa Clara, CA 95054

USA

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

HER2 (ERBB2) Stably Expressing Cell Lines. The proto-oncogene human epidermal growth factor receptor 2 (HER2) gene also known as ERBB2 is a member of the ERBB/HER RTK family which comprised of EGFR (EGFR/HER1/ERBB1), HER3/ERBB3 and HER4/ERBB4. This gene encodes for a transmembrane glycoprotein receptor with an intracellular domain with tyrosine kinase activity which is responsible for

SIGNOSIS

The GAL4-UAS system is a powerful technique for studying gene expression and function. It has also been adapted to study nuclear receptor chemical-binding functions. Signosis GAL4-UAS-luc Reporter Stable Cell Lines is a reliable, rapid, and sensitive method for analyzing the expression of your target gene upon exposure to related

ligands or

SIGNOSIS

Inflammation is the response of tissue to injury. During both acute and chronic inflammatory processes, a variety of soluble factors are involved in the cellular infiltrate, the cellular activation, and the systemic responses to inflammation. Cytokines are major determinants of inflammatory responses. Most cytokines are multifunctional

SIGNOSIS

Signosis has developed NRF2-reporter MCF7 stable cell line that has been stably transfected with pTA-NRF2-luciferase reporter vector, which contains 8 repeats of NRF2 binding sites, a minimal promoter upstream of the firefly luciferase coding region, along with a G418 expression vector. This cell line can be used to investigate oxidative

stress

SIGNOSIS

Product Name Catalog # Price Qty; p53 Snapshot Microplate ChIP Assay strips: CP-0110S: $232-+

SIGNOSIS

Cytokines that are secreted from cells bind to cell-surface receptors, initiate the activation of signal transduction pathways and mediate cell to cell communication. The malfunction of cytokines leads to many diseases, including arthritis, acute and chronic liver disease, inflammatory bowel disease, cardiac-related diseases, and cancers.

SIGNOSIS

Principle. The GAL4-UAS system is a powerful technique for studying of gene expression in some model organisms such as Drosophila. It can also be adapted to study

SIGNOSIS

Signosis has established NFAT luciferase reporter Jurkat T cell line that has been stably transfected with a NFAT-luciferase reporter construct. Via the analysis of luciferase, the cell line can be employed to monitor the cellular changes of NFAT activities that are triggered by stimulation, compound treatment, enforced gene expression

or gene

BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

It allows visualization of intact mRNA and provides a direct relative comparison of mRNA abundance between samples on a single membrane. The assay kits are non-radioactive with all reagents included, and the probes are biotin pre-labeled. No Isotope required - Safe method of detection using chemiluminescence. All reagents in one kit- Everything

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of

SIGNOSIS

Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen for the presence of serum ds-DNA antibodies IgG. Sample type: serum, plasma, cell culture supernatants and urine.

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSISSEE MORE ON SIGNOSISINC.COM BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

It allows visualization of intact mRNA and provides a direct relative comparison of mRNA abundance between samples on a single membrane. The assay kits are non-radioactive with all reagents included, and the probes are biotin pre-labeled. No Isotope required - Safe method of detection using chemiluminescence. All reagents in one kit- Everything

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of

SIGNOSIS

Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen for the presence of serum ds-DNA antibodies IgG. Sample type: serum, plasma, cell culture supernatants and urine.

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Signosis, Inc. 1700 Wyatt Drive, Suite # 10-12 Santa Clara, CA 95054

USA

SIGNOSIS

Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis. At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.

SIGNOSIS

No special requirement - Use standard laboratory instrument, Luminex is not needed. Works with Mammalian Nuclear Extracts- Samples can be taken from human, mouse, or rat and more. Product Name. Catalog #. Price. Qty. TF Activation Profiling Plate Array I. FA-1001. $583.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

Inflammation is the response of tissue to injury. During both acute and chronic inflammatory processes, a variety of soluble factors are involved in the cellular infiltrate, the cellular activation, and the systemic responses to inflammation. Cytokines are major determinants of inflammatory responses. Most cytokines are multifunctional

SIGNOSIS

Product Name Catalog # Price Qty; p53 Snapshot Microplate ChIP Assay strips: CP-0110S: $232-+

SIGNOSIS

Signosis’ TF Activation Profiling Arrays are used for monitoring the activities of multiple TFs simultaneously. In the technology, a series of biotin-labeled probes are made based on the consensus sequences of TF DNA-binding sites.

SIGNOSIS

Signosis has developed NRF2-reporter MCF7 stable cell line that has been stably transfected with pTA-NRF2-luciferase reporter vector, which contains 8 repeats of NRF2 binding sites, a minimal promoter upstream of the firefly luciferase coding region, along with a G418 expression vector. This cell line can be used to investigate oxidative

stress

SIGNOSIS

Signosis has established NFAT luciferase reporter Jurkat T cell line that has been stably transfected with a NFAT-luciferase reporter construct. Via the analysis of luciferase, the cell line can be employed to monitor the cellular changes of NFAT activities that are triggered by stimulation, compound treatment, enforced gene expression

or gene

SIGNOSIS

Filter Wash Buffer (FA-100X) Principle Data Literature. Product Name Catalog # Price Qty; Filter Wash Buffer (FA-100X) BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

It allows visualization of intact mRNA and provides a direct relative comparison of mRNA abundance between samples on a single membrane. The assay kits are non-radioactive with all reagents included, and the probes are biotin pre-labeled. No Isotope required - Safe method of detection using chemiluminescence. All reagents in one kit- Everything

SIGNOSIS

Signosis has generated a number of tumor cell lines expressing luciferase gene, facilitating evaluation of novel therapeutic modalities. These cell lines can be used to monitor carcinogenesis and tumor progression during metastasis or compare highly invasive and non-invasive tumor cells.

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of

SIGNOSIS

Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen for the presence of serum ds-DNA antibodies IgG. Sample type: serum, plasma, cell culture supernatants and urine.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Filter Wash Buffer (FA-100X) Principle Data Literature. Product Name Catalog # Price Qty; Filter Wash Buffer (FA-100X) BIOMARKER ANALYSIS, PLATE ASSAY DEVELOPMENT, ARRAYSPRODUCTSSERVICESMANUALSABOUT USCONTACT USLNCRNA REAL TIME PCR Gene Expression Analysis. Single Cell Gene Expression Analysis. Northern Blot Assay. SARS-CoV-2 Real Time PCR Detection Kit. cDNA Plate Arrays from RNA. Show me all. >.

SIGNOSIS

100+ non-radioactive EMSA Kits are available. The probes are pre-labeled with biotin, and all reagents are included in the kit. Benefits: Isotope free - It is a chemiluminescent-based detection.; No probe preparation - The probes included are pre-labeled and optimized.; Highly Sensitive - With optimized conditions, the kit sensitivity is compatible with that from radioactive-based detection

SIGNOSIS

It allows visualization of intact mRNA and provides a direct relative comparison of mRNA abundance between samples on a single membrane. The assay kits are non-radioactive with all reagents included, and the probes are biotin pre-labeled. No Isotope required - Safe method of detection using chemiluminescence. All reagents in one kit- Everything

SIGNOSIS

Signosis has generated a number of tumor cell lines expressing luciferase gene, facilitating evaluation of novel therapeutic modalities. These cell lines can be used to monitor carcinogenesis and tumor progression during metastasis or compare highly invasive and non-invasive tumor cells.

SIGNOSIS

Benefits: Multiplex - One pre-coated plate can measure 48 cytokines for 2 human samples, 32 cytokines for 3 human samples; 32 cytokines for 3 mouse samples, 24 cytokines for 4 mouse samples; or 16 cytokines for 6 rat samples. High Sensitivity - Requires minimal amount of sample. Quantitative profiling - Allows quantitative comparison of expression among samples.

SIGNOSIS

When they are present in high concentration, anti-dsDNA antibodies are virtually specific for SLE (>90%). Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen the presence of

SIGNOSIS

Antibodies to dsDNA may disappear with immunosuppressive treatment and during remission. They rarely occur in other autoimmune disorders. Signosis has developed anti-dsDNA ELISA, a sandwich quantitative assay, to screen for the presence of serum ds-DNA antibodies IgG. Sample type: serum, plasma, cell culture supernatants and urine.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSISSEE MORE ON SIGNOSISINC.COM

SIGNOSIS

Filter Wash Buffer (FA-100X) Principle Data Literature. Product Name Catalog # Price Qty; Filter Wash Buffer (FA-100X)

ABOUT US - SIGNOSIS

About Us. Signosis is a leader of bioassay provider over a decade, dedicated to the development and commercialization of plate-based analysis products in the life sciences community. We focus on many regulatory key molecules: transcription factors, cytokines, miRNAs, and disease markers. Our mission is to provide excellent products and service worldwide, which include scientists in

SIGNOSIS

Custom Service: Assay Development. TF Profiling Arrays. EMSA. TF Filter Assays. Cytokine ELISA Plate Arrays. Cytokine ELISA Strips. miRNA Arrays. miRNA Northern Blot Assay Kits. miRNA Real-Time PCR.

SIGNOSIS

Disruption in these signals can lead to a variety of diseases, including arthritis, liver disease, inflammatory bowel disease, cardiac-related diseases, and cancers. Signosis provides a number of tools to profile one specific cytokine or growth factor, or to monitor multiple simultaneously. See our ELISA biomarker kit

SIGNOSIS

Benefits: *New Quantitative Analysis - Antibody standard is now provided for calibration curve with NO extra cost. Cost-effective analysis - High quality with an affordable price. Efficient and flexible - Multiple samples can be analyzed simultaneously with a flexible number of assay wells. Simple procedure - All in one system

with a pre-coated

SIGNOSIS

Promoter Binding TF Profiling Plate Arrays. Determine whether 48 or 96 TFs bind to a promoter or not. Benefits: Multiplex - A single assay allows the characterization of binding of 48 or 96 TFs to a specific promoter. Simple procedures - Probe incubation, spin column separation, plate hybridization, and HRP detection. Product Name.

SIGNOSIS

Benefits: Multiplex - One ELISA strip allows the measurement of 8 cytokines. Flexible - Comparisons can be made between 2 to 12 samples. Quantitative profiling - Allows quantitative comparison of expression among samples. Simple procedure - Straightforward procedures with all reagents provided.; Quantitative analysis - Protein standard is available for purchase separately.

SIGNOSIS

Signosis has established a TCF/LEF luciferase reporter stable cell line that has been stably transfected with pTA-TCF/LEF-luciferase reporter vector, which contains 6 repeats of TCF/LEF binding sites, a minimal promoter upstream of the firefly luciferase coding region. Therefore, the cell line can be used as a reporter system for

monitoring the

SIGNOSIS

Disruption in the activity levels can lead to a variety of diseases, including arthritis, liver disease, inflammatory bowel disease, cardiac-related diseases, and cancers. Therefore, tools to study kinase pathways and activities can improve our understanding of kinases and facilitate drug discoveries. Signosis provides a number of

tools to

SIGNOSIS

Inflammation is the response of tissue to injury. During both acute and chronic inflammatory processes, a variety of soluble factors are involved in the cellular infiltrate, the cellular activation, and the systemic responses to inflammation. Cytokines are major determinants of inflammatory responses. Most cytokines are multifunctional

SIGNOSIS

EGFR Stably Expressing Cell Lines. EGFR mutations occur in many type of cancers including non-small cell lung cancer. Common mutations found in these patients are deletions in exon 19 (Del19) and L858R substitution in exon 21. Patients with these mutations are sensitive to first (gefitinib or erlotinib) and second (afatinib) generation

EGFR

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INNOVATIVE RESEARCH TOOLS For your complex scientific questions

CELL-BASED ASSAYS

* Luciferase Reporter Stable Cell Lines * EGFR Stably Expressing Cell Lines * pLenti-MSCV-EGFR-GFP

* pCMV-EGFR

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TRANSCRIPTION FACTOR ASSAYS * TF Activation Profiling Plate Arrays * Promoter Binding TF Profiling Plate Arrays * TF Interaction Plate Arrays

* EMSA

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CYTOKINES ELISA

* Cytokine ELISA Plate Arrays * Human Cytokine ELISA Strips * Mouse Cytokine ELISA Strips * Rat Cytokine ELISA Strips

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MIRNA RESEARCH

* lncRNA Northern Blot Assay * lncRNA Real Time PCR * miRNA Real Time PCR * miRNA Northern Blot Assays

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GENE EXPRESSION ANALYSIS * Northern Blot Assay * Single Cell Gene Expression Analysis * cDNA Plate Arrays from RNA * cDNA Plate Arrays from Cell Lysates BIOMARKERS & KEY PROTEINS * Mouse Autoimmune ELISA Kits * Mouse Tumor Marker ELISA Kits * Mouse Cardiac Marker ELISA Kits * Mouse Hormones & Steroids ELISA Kits

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KINASE PATHWAY EXPLORATION * Kinase TAD Luciferase Reporter Stable Cell Line * Kinase TAD Luciferase Reporter Vectors * Signaling Protein Assay Kits

OTHERS

* Signosis Luciferase Substrate * Cell Viability Cytotoxicity (CVC) Reagent

* Components

DISCOVER YOUR PLATE ASSAY WITH US WELCOME TO OUR NEWLY REDESIGNED WEBSITE STABLE CELL LINE GENERATION

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PRODUCTS

* Cell-Based Assays

* Transcription Factor Assays

* Cytokines ELISA

* miRNA Research

* Gene Expression Analysis * Biomarkers & Key Proteins

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Toll Free: 1-877-266-8388 Phone: 1-408-747-0771

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