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HYDROXYCHLOROQUINE PHARMACOLOGY Hydroxychloroquine Pharmacology. Hydroxychloroquine is classified as a DMARD and when used chronically, can be helpful in managing rheumatoid arthritis and Lupus. There have been reports of QTc prolongation with hydroxychloroquine. While not incredibly common, it is important to remember this consideration in patients at risk for QTc prolongation. EMPAGLIFLOZIN PHARMACOLOGY Empagliflozin Pharmacology. On this episode I discuss empagliflozin pharmacology and how this medication lowers blood sugar. Empagliflozin is associated with an increased risk of genitourinary tract infections. Be aware that patients who are prone to hypotension, may have an increased risk of this issue with empagliflozin use.Empagliflozin has
IRON SUPPLEMENT PHARMACOLOGY Iron Supplement Pharmacology. Iron supplements frequently cause GI upset. Monitor patients for nausea, vomiting, and constipation issues. There are three main salt forms of iron. Ferrous fumurate has the most elemental iron, ferrous sulfate (2nd most), and ferrous gluconate has the least. Iron can bind up antibiotics and reduce theireffectiveness.
DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
HYDROXYCHLOROQUINE PHARMACOLOGY Hydroxychloroquine Pharmacology. Hydroxychloroquine is classified as a DMARD and when used chronically, can be helpful in managing rheumatoid arthritis and Lupus. There have been reports of QTc prolongation with hydroxychloroquine. While not incredibly common, it is important to remember this consideration in patients at risk for QTc prolongation. EMPAGLIFLOZIN PHARMACOLOGY Empagliflozin Pharmacology. On this episode I discuss empagliflozin pharmacology and how this medication lowers blood sugar. Empagliflozin is associated with an increased risk of genitourinary tract infections. Be aware that patients who are prone to hypotension, may have an increased risk of this issue with empagliflozin use.Empagliflozin has
IRON SUPPLEMENT PHARMACOLOGY Iron Supplement Pharmacology. Iron supplements frequently cause GI upset. Monitor patients for nausea, vomiting, and constipation issues. There are three main salt forms of iron. Ferrous fumurate has the most elemental iron, ferrous sulfate (2nd most), and ferrous gluconate has the least. Iron can bind up antibiotics and reduce theireffectiveness.
DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
FOLIC ACID PHARMACOLOGY On this episode, I discuss folic acid pharmacology, clinical pearls, and important drug induced causes of deficiency. Folic acid deficiencycan be caused by
EMPAGLIFLOZIN PHARMACOLOGY Empagliflozin Pharmacology. On this episode I discuss empagliflozin pharmacology and how this medication lowers blood sugar. Empagliflozin is associated with an increased risk of genitourinary tract infections. Be aware that patients who are prone to hypotension, may have an increased risk of this issue with empagliflozin use.Empagliflozin has
MELATONIN PHARMACOLOGY Nursing Professionals Dietitian Professionals. Resources. Information is taken directly from the podcast episode; Light/dark melatonin levels, concentrations with age paragraph 1: 10.1016/s0531-5565(98)00054-0 , podcast ADRs paragraph 2: Lexicomp,podcast
PSYCH – REAL LIFE PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss escitalopram pharmacology. Escitalopram is an SSRI and can be used to manage depression, anxiety, OCD, PTSD, and other psychiatric disorders. If you consider fluoxetine the most activation SSRI and paroxetine the most sedating, escitalopram probably falls somewhere inthe middle.
FUROSEMIDE PHARMACOLOGY Furosemide Pharmacology. Furosemide is a loop diuretic most commonly recognized by its brand name, Lasix. Pharmacologically, it acts by inhibiting the reabsorption of Na/Cl in the thick ascending limb of the loop of Henle. The inhibition of electrolyte reabsorption results in a loss of fluids causing diuresis. Since it has a diuretic effect,it
ZOLPIDEM PHARMACOLOGY Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors. Concentrations can rise on REAL LIFE PHARMACOLOGY PODCAST Real Life Pharmacology Podcast; A Meded101.com Production REAL LIFE PHARMACOLOGY PODCAST – TOP 200 STUDY GUIDE Furosemide (Lasix) •Blocks reabsorption of sodium, chloride and CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. NICOTINE PATCH PHARMACOLOGY Nicotine patches differ from the gum and other acute relief forms in that they are intended to provide a consistent level of nicotine in the body. The initial dosing of nicotine patches is dependent upon the number of cigarettes smoked by the patient. I discuss it further in the podcast. When applying nicotine patches, it is important to PSEUDOEPHEDRINE PHARMACOLOGY Pseudoephedrine Pharmacology. Pseudoephedrine is commonly used to help relieve nasal congestion. There are some adverse effects you need to be aware of with pseudoephedrine. Insomnia, increase in blood pressure, and urinary retention are all possible. When I assess a patient using pseudoephedrine, I like to investigate blood pressure,history
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants HYDROXYCHLOROQUINE PHARMACOLOGY Hydroxychloroquine Pharmacology. Hydroxychloroquine is classified as a DMARD and when used chronically, can be helpful in managing rheumatoid arthritis and Lupus. There have been reports of QTc prolongation with hydroxychloroquine. While not incredibly common, it is important to remember this consideration in patients at risk for QTc prolongation. FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. IBUPROFEN PHARMACOLOGY Ibuprofen Pharmacology. On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, ibuprofen has a relatively short half-life. This explains why it needs to be dosed more frequently than other agents. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
PSEUDOEPHEDRINE PHARMACOLOGY Pseudoephedrine Pharmacology. Pseudoephedrine is commonly used to help relieve nasal congestion. There are some adverse effects you need to be aware of with pseudoephedrine. Insomnia, increase in blood pressure, and urinary retention are all possible. When I assess a patient using pseudoephedrine, I like to investigate blood pressure,history
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants HYDROXYCHLOROQUINE PHARMACOLOGY Hydroxychloroquine Pharmacology. Hydroxychloroquine is classified as a DMARD and when used chronically, can be helpful in managing rheumatoid arthritis and Lupus. There have been reports of QTc prolongation with hydroxychloroquine. While not incredibly common, it is important to remember this consideration in patients at risk for QTc prolongation. FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. IBUPROFEN PHARMACOLOGY Ibuprofen Pharmacology. On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, ibuprofen has a relatively short half-life. This explains why it needs to be dosed more frequently than other agents. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
PSEUDOEPHEDRINE PHARMACOLOGY Pseudoephedrine Pharmacology. Pseudoephedrine is commonly used to help relieve nasal congestion. There are some adverse effects you need to be aware of with pseudoephedrine. Insomnia, increase in blood pressure, and urinary retention are all possible. When I assess a patient using pseudoephedrine, I like to investigate blood pressure,history
FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
PSYCH – REAL LIFE PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss escitalopram pharmacology. Escitalopram is an SSRI and can be used to manage depression, anxiety, OCD, PTSD, and other psychiatric disorders. If you consider fluoxetine the most activation SSRI and paroxetine the most sedating, escitalopram probably falls somewhere inthe middle.
IBUPROFEN PHARMACOLOGY Ibuprofen Pharmacology. On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, ibuprofen has a relatively short half-life. This explains why it needs to be dosed more frequently than other agents. FUROSEMIDE PHARMACOLOGY Furosemide Pharmacology. Furosemide is a loop diuretic most commonly recognized by its brand name, Lasix. Pharmacologically, it acts by inhibiting the reabsorption of Na/Cl in the thick ascending limb of the loop of Henle. The inhibition of electrolyte reabsorption results in a loss of fluids causing diuresis. Since it has a diuretic effect,it
IRON SUPPLEMENT PHARMACOLOGY Iron Supplement Pharmacology. Iron supplements frequently cause GI upset. Monitor patients for nausea, vomiting, and constipation issues. There are three main salt forms of iron. Ferrous fumurate has the most elemental iron, ferrous sulfate (2nd most), and ferrous gluconate has the least. Iron can bind up antibiotics and reduce theireffectiveness.
KETAMINE PHARMACOLOGY Ketamine can cause psychiatric type adverse effects such as hallucinations, nightmares, and vivid dreams. At lower to moderate dosages, ketamine does have some mild sympathetic activity which can raise blood pressure and heart rate. I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page TOPIRAMATE PHARMACOLOGY Topiramate Pharmacology. On this episode of the Real Life Pharmacology Podcast, I cover topiramate pharmacology. Topiramate is indicated for migraine prevention, seizures, and weight loss which are the most common uses that I see this medication used for. Topiramate has carbonic anhydrase activity, so rarely, use of this drug may induce VITAMIN B12 PHARMACOLOGY Vitamin B12 Pharmacology. On this episode, I cover clinical tips and practice pearls surrounding vitamin B12 pharmacology. Vitamin B12 deficiency plays a critical role in the development of macrocytic anemia. There are medications that you have to be aware that can deplete vitamin B12. Metformin, colchicine, and PPIs are some commonexamples.
ZOLPIDEM PHARMACOLOGY Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors. Concentrations can rise on NICOTINE PATCH PHARMACOLOGY Nicotine patches differ from the gum and other acute relief forms in that they are intended to provide a consistent level of nicotine in the body. The initial dosing of nicotine patches is dependent upon the number of cigarettes smoked by the patient. I discuss it further in the podcast. When applying nicotine patches, it is important to REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
IBUPROFEN PHARMACOLOGY Ibuprofen Pharmacology. On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, ibuprofen has a relatively short half-life. This explains why it needs to be dosed more frequently than other agents. DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. NITROFURANTOIN PHARMACOLOGY Nitrofurantoin is an antibiotic that is used in the treatment of UTI’s. Nitrofurantoin has activity by creating reactive metabolites that can disrupt protein synthesis and ultimately kills the bacteria causing the infection. It is important to remember with nitrofurantoin, that in the setting of systemic infection and/orkidney involvement
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
NICOTINE PATCH PHARMACOLOGY Nicotine patches differ from the gum and other acute relief forms in that they are intended to provide a consistent level of nicotine in the body. The initial dosing of nicotine patches is dependent upon the number of cigarettes smoked by the patient. I discuss it further in the podcast. When applying nicotine patches, it is important to TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
IBUPROFEN PHARMACOLOGY Ibuprofen Pharmacology. On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, ibuprofen has a relatively short half-life. This explains why it needs to be dosed more frequently than other agents. DIAZEPAM PHARMACOLOGY Diazepam Pharmacology. Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. SILDENAFIL PHARMACOLOGY Sildenafil Pharmacology. On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast. Sildenafil can cause rare visual changes thatpatients should be
CLOZAPINE PHARMACOLOGY Clozapine Pharmacology. On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking activity all contribute to the complexity of this drug. Smoking cessation can significantly increase the concentrations of clozapine. NITROFURANTOIN PHARMACOLOGY Nitrofurantoin is an antibiotic that is used in the treatment of UTI’s. Nitrofurantoin has activity by creating reactive metabolites that can disrupt protein synthesis and ultimately kills the bacteria causing the infection. It is important to remember with nitrofurantoin, that in the setting of systemic infection and/orkidney involvement
TACROLIMUS PHARMACOLOGY Tacrolimus has a long list of potential adverse effects such as hyperglycemia, renal impairment, GI toxicity, and hypertriglyceridemia. Important monitoring parameters for tacrolimus include drug levels, electrolytes, renal function, and blood sugars. CYP3A4 interactions are critical with tacrolimus. Inhibitors can raiseconcentrations and
NICOTINE PATCH PHARMACOLOGY Nicotine patches differ from the gum and other acute relief forms in that they are intended to provide a consistent level of nicotine in the body. The initial dosing of nicotine patches is dependent upon the number of cigarettes smoked by the patient. I discuss it further in the podcast. When applying nicotine patches, it is important to TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
ABOUT – REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
TOPIRAMATE PHARMACOLOGY Topiramate Pharmacology. On this episode of the Real Life Pharmacology Podcast, I cover topiramate pharmacology. Topiramate is indicated for migraine prevention, seizures, and weight loss which are the most common uses that I see this medication used for. Topiramate has carbonic anhydrase activity, so rarely, use of this drug may induce SUBSCRIBE TO PODCAST Subscribe to Podcast. By subscribing to this podcast, you will automatically receive the latest episodes downloaded to your computer or portable device. Select the OLANZAPINE PHARMACOLOGY Olanzapine Pharmacology. Olanzapine is a 2nd generation antipsychotic that blocks dopamine-2 receptors. Olanzapine Relprevv (long acting injectable) needs to be closely monitored after the injection is given due to risks of sedation and delirium. Sedation is a common occurance with the use of olanzapine. It is one of the more sedating second VITAMIN B12 PHARMACOLOGY Vitamin B12 Pharmacology. On this episode, I cover clinical tips and practice pearls surrounding vitamin B12 pharmacology. Vitamin B12 deficiency plays a critical role in the development of macrocytic anemia. There are medications that you have to be aware that can deplete vitamin B12. Metformin, colchicine, and PPIs are some commonexamples.
TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
NAPROXEN PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss naproxen pharmacology. Naproxen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, naproxen tends to have a lower cardiovascular risk. Naproxen can contribute to renal insufficiency, GI bleed risk, and CHFexacerbations.
ZOLPIDEM PHARMACOLOGY Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors. Concentrations can rise on DONEPEZIL PHARMACOLOGY Donepezil is an acetylcholinesterase inhibitor. In dementia, that is a deficiency in acetylcholine and donepezil helps preserve this neurotransmitter. Donepezil can cause weight loss, GI upset, and diarrhea. This is an important monitoring parameter in our dementia patients. There is the possibility for donepezil to cause bradycardiaand insomnia.
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, IBUPROFEN PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase DIAZEPAM PHARMACOLOGY Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 SILDENAFIL PHARMACOLOGY On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to l TACROLIMUS PHARMACOLOGY On this episode, I discuss tacrolimus pharmacology. This medication is an immunosuppressant used to reduce the risk of transplant rejection. Tacrolimus has a long list of potential adverse effects CLOZAPINE PHARMACOLOGY On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergicactivity, and
NICOTINE PATCH PHARMACOLOGY Nicotine replacement therapy is an important tool in helping our patients quit smoking. There are lots of clinical pearls involving the pharmacology of nicotine patches and I TAMSULOSIN PHARMACOLOGY On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in NITROFURANTOIN PHARMACOLOGY On this episode I breakdown nitrofurantoin pharmacology. Nitrofurantoin is an antibiotic that is used in the treatment of UTI’s. Nitrofurantoin has activity by creating reactive metabolitest
REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, IBUPROFEN PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss ibuprofen pharmacology. Ibuprofen can raise the concentrations of lithium and increase DIAZEPAM PHARMACOLOGY Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2 SILDENAFIL PHARMACOLOGY On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions. Sildenafil’s most common and concerning adverse effect is in relation to its ability to l TACROLIMUS PHARMACOLOGY On this episode, I discuss tacrolimus pharmacology. This medication is an immunosuppressant used to reduce the risk of transplant rejection. Tacrolimus has a long list of potential adverse effects CLOZAPINE PHARMACOLOGY On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergicactivity, and
NICOTINE PATCH PHARMACOLOGY Nicotine replacement therapy is an important tool in helping our patients quit smoking. There are lots of clinical pearls involving the pharmacology of nicotine patches and I TAMSULOSIN PHARMACOLOGY On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in NITROFURANTOIN PHARMACOLOGY On this episode I breakdown nitrofurantoin pharmacology. Nitrofurantoin is an antibiotic that is used in the treatment of UTI’s. Nitrofurantoin has activity by creating reactive metabolitest
ABOUT – REAL LIFE PHARMACOLOGY The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog, Meded101.com.. In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants FREE TOP 200 STUDY GUIDE (31 PAGES) Free Top 200 Study Guide (31 Pages) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following thepodcast!
TOPIRAMATE PHARMACOLOGY Topiramate Pharmacology. On this episode of the Real Life Pharmacology Podcast, I cover topiramate pharmacology. Topiramate is indicated for migraine prevention, seizures, and weight loss which are the most common uses that I see this medication used for. Topiramate has carbonic anhydrase activity, so rarely, use of this drug may induce SUBSCRIBE TO PODCAST Subscribe to Podcast. By subscribing to this podcast, you will automatically receive the latest episodes downloaded to your computer or portable device. Select the OLANZAPINE PHARMACOLOGY Olanzapine Pharmacology. Olanzapine is a 2nd generation antipsychotic that blocks dopamine-2 receptors. Olanzapine Relprevv (long acting injectable) needs to be closely monitored after the injection is given due to risks of sedation and delirium. Sedation is a common occurance with the use of olanzapine. It is one of the more sedating second VITAMIN B12 PHARMACOLOGY Vitamin B12 Pharmacology. On this episode, I cover clinical tips and practice pearls surrounding vitamin B12 pharmacology. Vitamin B12 deficiency plays a critical role in the development of macrocytic anemia. There are medications that you have to be aware that can deplete vitamin B12. Metformin, colchicine, and PPIs are some commonexamples.
TAMSULOSIN PHARMACOLOGY Tamsulosin Pharmacology. On this episode of the RLP podcast, I discuss tamsulosin pharmacology. Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH. As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones. Tamsulosin concentrations may be increased by CYP3A4inhibitors
NAPROXEN PHARMACOLOGY On this episode of the Real Life Pharmacology Podcast, I discuss naproxen pharmacology. Naproxen can raise the concentrations of lithium and increase the risk for toxicity. Compared to most other NSAIDs, naproxen tends to have a lower cardiovascular risk. Naproxen can contribute to renal insufficiency, GI bleed risk, and CHFexacerbations.
ZOLPIDEM PHARMACOLOGY Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors. Concentrations can rise on DONEPEZIL PHARMACOLOGY Donepezil is an acetylcholinesterase inhibitor. In dementia, that is a deficiency in acetylcholine and donepezil helps preserve this neurotransmitter. Donepezil can cause weight loss, GI upset, and diarrhea. This is an important monitoring parameter in our dementia patients. There is the possibility for donepezil to cause bradycardiaand insomnia.
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No matter the healthcare profession, pharmacology is likely one of the most challenging courses you will ever take. The Real Life Pharmacology podcast was born out of the idea that students and young healthcare professionals don’t get enough real world experience prior to going out on their own. Pharmacology in college is often taught by professors who haven’t worked in the real world in decades. In addition to helping you understand pharmacology and pass exams, the Real Life Pharmacology podcast will help you get a sense of what actually happens in “real life”. Facebook Twitter LinkedIn EmailPinterest Share
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Posted on May 28, 2020May 5, 2020 RIVASTIGMINE PHARMACOLOGY Podcast: Play in new window | Download (Duration: 13:42 — 11.5MB) | EmbedSubscribe: Apple Podcasts | Android | Google Podcasts | Stitcher | RSS | MoreRivastigmine is an acetylcholinesterase inhibitor used in the management of certain dementias. I discuss rivastigmine pharmacology on this episode. Weight loss is a potential adverse effect of rivastigmine. It is … Continue reading “Rivastigmine Pharmacology” Facebook Twitter LinkedIn EmailPinterest Share
Posted on May 21, 2020May 5, 2020 CAFFEINE PHARMACOLOGY Podcast: Play in new window | Download (Duration: 13:12 — 11.1MB) | EmbedSubscribe: Apple Podcasts | Android | Google Podcasts | Stitcher | RSS | MoreCaffeine is a commonly used supplement and is found in many food and beverages. I discuss caffeine pharmacology, adverse effects, and drug interactions. Caffeine can inhibit CYP1A2 and alsobe …
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Posted on May 14, 2020April 30, 2020 COLESTIPOL PHARMACOLOGY Podcast: Play in new window | Download (Duration: 12:00 — 10.1MB) | EmbedSubscribe: Apple Podcasts | Android | Google Podcasts | Stitcher | RSS | MoreColestipol is a bile acid sequestrant that can be used in the management of hyperlipidemia. By binding bile acid in the gut, colestipol can lower LDL that is bound to … Continue reading “Colestipol Pharmacology” Facebook Twitter LinkedIn EmailPinterest Share
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The Real Life Pharmacology podcast was created by Eric Christianson, PharmD. He’s been acknowledged in the Wall Street Journal, American Journal of Nursing, Pharmacy Times, written an Amazon #1 best seller, and is the author of the #1 clinical pharmacy blog,
Meded101.com . In addition, he’s actually worked in the real world with physicians, nurse practitioners, nurses, physician assistants, and other pharmacists trying to solve difficult medication related problems. He loves to teach and share real life examples to help students and young professionals take better care of their patients. Facebook Twitter LinkedIn EmailPinterest Share
FREE TOP 200 STUDY GUIDE (31 PAGES) All subscribers to the website/podcast will get access to a Top 200 Drug Study Guide where I highlight the 3 most highly testable pearls from each medication (this is a 31 page PDF!) In addition, you’ll get a free 100 question pharmacology test. Both resources are free, simply for following the podcast! What are you waiting for? ClickHere to Subscribe
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