OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS StarDrop helps you to deliver optimally balanced, successful compounds, fast. StarDrop enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

ABOUT | OPTIBRIUM

StarDropâ„¢, which brings confidence to the selection and design of high-quality candidate compounds.StarDrop creates an intuitive, highly visual and flexible environment to facilitate and speed up lead identification and optimisation, quickly targeting effective candidate compounds with a high probability of success downstream. STARDROP | OPTIBRIUM With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop â„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. TUTORIALS | OPTIBRIUM The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. PROBABILISTIC SCORING StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. STUNNINGLY EASY WESTERN BLOT IMAGING Stunningly easy western blot imaging Simplify western blot imaging with iBright Imaging Systems • Push-button, optimized exposure • User-focused, intuitive interface and workflows PREDICTING PKA IN STARDROP’S ADME QSAR MODULE This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants

for your compounds.

OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS StarDrop helps you to deliver optimally balanced, successful compounds, fast. StarDrop enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

ABOUT | OPTIBRIUM

StarDropâ„¢, which brings confidence to the selection and design of high-quality candidate compounds.StarDrop creates an intuitive, highly visual and flexible environment to facilitate and speed up lead identification and optimisation, quickly targeting effective candidate compounds with a high probability of success downstream. STARDROP | OPTIBRIUM With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop â„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. TUTORIALS | OPTIBRIUM The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. PROBABILISTIC SCORING StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. STUNNINGLY EASY WESTERN BLOT IMAGING Stunningly easy western blot imaging Simplify western blot imaging with iBright Imaging Systems • Push-button, optimized exposure • User-focused, intuitive interface and workflows PREDICTING PKA IN STARDROP’S ADME QSAR MODULE This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants

for your compounds.

LOGIN | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. TUTORIALS | OPTIBRIUM The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

MODULES | OPTIBRIUM

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

OCURA | OPTIBRIUM

Within Ocura data can be organised, sorted and viewed according to the your own preferences. Multiple data sheets can be opened at the same time, while properties DOWNLOADS | OPTIBRIUM In this section, we provide free add-ons for StarDrop which include models that our users have developed and scripts that bring additional functionality (such as running proprietary or third party models, interacting with Pipeline Pilot, etc.)

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users.

SEESAR | OPTIBRIUM

The SeesAR modules for StarDrop provide state-of-the-art and scientifically rigorous approaches to understanding the 3D binding of your compounds to their protein targets.

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. FINDING THE RULES FOR SUCCESSFUL DRUG OPTIMIZATION Finding the Rules for Successful Drug Optimization Iskander Yusof*, Falgun Shah†, Tatsu Hashimoto‡, Matthew D. Segall* and Nigel Greene† *Optibrium Ltd., 7221 Cambridge Research Park, Beach Drive, Cambridge, CB25 9TL,UK OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's LARGE SCALE IMPUTATION OF DRUG DISCOVERY DATA USING DEEP Held on 26 May 2020. This webinar was presented by Ben Irwin and Matthew Segall (Optibrium), Tom Whitehead (Intellegens) and Scott Rowland (Takeda Pharmaceutical).

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's LARGE SCALE IMPUTATION OF DRUG DISCOVERY DATA USING DEEP Held on 26 May 2020. This webinar was presented by Ben Irwin and Matthew Segall (Optibrium), Tom Whitehead (Intellegens) and Scott Rowland (Takeda Pharmaceutical).

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUG The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

MODULES | OPTIBRIUM

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. REGISTER | OPTIBRIUM E-mail Address. Password. Confirm Password. Only fill in if you are not human. Login. Join The. Optibrium Community. Access a wealth of information on all of our products, learn more about our science and our wider community of collaborators. .

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. THIS EXAMPLE DEMONSTRATES HOW STARDROP’S SEESAR AFFINITY 4 • From the Display menu, choose Display Options. • In the Display Options dialogue, tick the Show protein surface option and choose Transparent and Colour by LogP from the menus. • Close the Display Option dialogue. This data set already contains a column showing docking scores; however, these values don’t necessarily provide a good indication as to the binding affinity we might expect. BRIDGING THE DIMENSIONS © 2016 Optibrium Ltd. Qualitative SAR Many methods are routinely used for analysis of data to reveal patterns and trends to guide compound

optimisation, e.g.

ADVANCES IN MULTI-PARAMETER OPTIMISATION METHODS FOR DE 7221 Cambridge Research Park Beach Drive, Cambridge Website: CB25 9TL, UK Tel: +44 1223 815900 Fax: +44 1223 815907 Email: info@optibrium.com

www.optibrium.com

OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDropâ„¢ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's LARGE SCALE IMPUTATION OF DRUG DISCOVERY DATA USING DEEP Held on 26 May 2020. This webinar was presented by Ben Irwin and Matthew Segall (Optibrium), Tom Whitehead (Intellegens) and Scott Rowland (Takeda Pharmaceutical).

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. STARDROP SOLUBILITY MODELS 2 StarDrop solubility models Current - version 4.2 and previous • Intrinsic aqueous solubility logS (S in μM) (solubility of neutral form) • Apparent solubility at pH 7.4 logS@7.4 (S in μM) OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's LARGE SCALE IMPUTATION OF DRUG DISCOVERY DATA USING DEEP Held on 26 May 2020. This webinar was presented by Ben Irwin and Matthew Segall (Optibrium), Tom Whitehead (Intellegens) and Scott Rowland (Takeda Pharmaceutical).

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look.

MODULES | OPTIBRIUM

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

INTEGRATION

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. REGISTER | OPTIBRIUM E-mail Address. Password. Confirm Password. Only fill in if you are not human. Login. Join The. Optibrium Community. Access a wealth of information on all of our products, learn more about our science and our wider community of collaborators. .

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. ADME QSAR | OPTIBRIUM This module enables you to predict a broad range of ADME and physicochemical properties using a suite of high-quality QSAR models including: pKa- Most acidic pKa. – Most basic pKa- All pKa values. logP (Octanol/Water) logD7.4 (Octanol/buffer at pH 7.4) Solubility. – Aqueous Solubility. – PBS Solubility pH 7.4. Human Intestinal

Absorption.

REACTION-BASED LIBRARY ENUMERATION WEBINAR This webinar was presented by Matt Segall, Peter Hunt and Imants Zudans. In this webinar, we demonstrated how to generate virtual libraries by applying tractable, robust chemical reactions to readily available building blocks in a highly flexible and user-friendly environment.. We were joined by Imants Zudans, CEO of Molport, who described Molport’s compound sourcing services and the

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users.

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users.

INTEGRATION

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free.

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look.

LOGIN | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's REGISTER | OPTIBRIUM E-mail Address. Password. Confirm Password. Only fill in if you are not human. Login. Join The. Optibrium Community. Access a wealth of information on all of our products, learn more about our science and our wider community of collaborators. .

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

SEESAR | OPTIBRIUM

SeeSAR is a suite of three modules which seamlessly interact to help you visualise and predict protein-ligand interactions in 3D. Visualise your ligands in their protein environment to identify the key interactions driving binding affinity in 3D. These structures can be derived from X-ray crystallography or predicted with any docking

software.

R-GROUP ANALYSIS

R-group Analysis. Jun 1, 2018. StarDrop’s R-group analysis makes it quick and easy to explore the variation of properties by the substituents within a chemical series. This video shows how to perform an R-group decomposition and create SAR plots. The next video in this short series, illustrates how to create information-rich SAR plots. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users.

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users.

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look.

LOGIN | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's REGISTER | OPTIBRIUM E-mail Address. Password. Confirm Password. Only fill in if you are not human. Login. Join The. Optibrium Community. Access a wealth of information on all of our products, learn more about our science and our wider community of collaborators. .

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

SURFLEX ESIM3D

With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDropâ„¢ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

SEESAR | OPTIBRIUM

SeeSAR is a suite of three modules which seamlessly interact to help you visualise and predict protein-ligand interactions in 3D. Visualise your ligands in their protein environment to identify the key interactions driving binding affinity in 3D. These structures can be derived from X-ray crystallography or predicted with any docking

software.

R-GROUP ANALYSIS

R-group Analysis. Jun 1, 2018. StarDrop’s R-group analysis makes it quick and easy to explore the variation of properties by the substituents within a chemical series. This video shows how to perform an R-group decomposition and create SAR plots. The next video in this short series, illustrates how to create information-rich SAR plots. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. OPTIBRIUM | ELEGANT SOFTWARE THAT GUIDES SUCCESSFUL DRUGCOMMUNITYNEWSCONTACTOCURAPUBLICATIONS & PRESENTATIONSTUTORIALS The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. StarDrop™ is a complete package of fully integrated, elegant software for small molecule design, optimisation and data analysis.

ABOUT | OPTIBRIUM

About. Optibrium. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis, to guide decisions and improve efficiency in drug discovery. about us. An Introduction. Founded in 2009, Optibrium is headquartered in Cambridge, UK with offices in Boston, US. We continue to develop new

products and

STARDROP | OPTIBRIUM Stardrop | Optibrium. A complete platform for small molecule design, optimisation and data analysis. Deliver optimally balanced, successful compounds, fast. With its comprehensive suite of integrated software, StarDropâ„¢ delivers best-in-class in silico technologies within a

OCURA | OPTIBRIUM

Ocura | Optibrium. Look at your compounds in a new way. A desktop application for viewing chemistry data. This free and easy-to-use Windows® and Mac® desktop application is specifically designed for scientists who want a simple way to load a set of molecule structures and easily browse through the data. Available to. Download For Free. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

DOWNLOADS | OPTIBRIUM View Download. This calculates the number of aromatic rings in a compound. This has been proposed by Ritchie and Macdonald as a characteristic that is View Download. This script provides a method for calculating Lipophilicity Efficiency; a simple metric for considering how much of the ligand's

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

BIOSTER | OPTIBRIUM

This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of over 20,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. PREDICTING PKA IN STARDROP’S ADME QSAR MODULE Predicting pKa in StarDrop’s ADME QSAR module. Oct 22, 2019. This short video gives an introduction to the model of pK a in StarDrop’s ADME QSAR module. This model combines quantum mechanics and machine learning to accurately predict acid dissociation constants for your compounds. Modules and Features: Predicting pKa. PROBABILISTIC SCORING Probabilistic Scoring. Oct 16, 2013. StarDrop’s probabilistic scoring is a powerful multi-parameter optimisation (MPO) technique but we’ve made it really easy to use so that you can find out which compounds have the best balance of properties. Take a look. TUTORIALS | OPTIBRIUM Oct 16, 2013. This example explores the application of the Auto-Modeller module to build a QSAR model of potency against the Muscurinic Acetylcholine View Tutorial. R-Group Analysis. Oct 16, 2013. In this example we look at R-Group analysis of chemical series

to

VIDEOS | OPTIBRIUM

The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery.

INTEGRATION

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. COMMUNITY | OPTIBRIUM Whether you’re a StarDrop, Cerella or Ocura user or just want to know more, this community has been set up to provide you with direct access to the Optibrium support team and other users. REGISTER | OPTIBRIUM E-mail Address. Password. Confirm Password. Only fill in if you are not human. Login. Join The. Optibrium Community. Access a wealth of information on all of our products, learn more about our science and our wider community of collaborators. . CONTACT US | OPTIBRIUM The Optibrium team works at the forefront of decision-analysis and predictive modelling research, developing innovative products that enhance the efficiency and productivity of drug discovery. ARCHIVES | OPTIBRIUM Recent Posts. Data visualisation: Saying it all in a bite-sized chunk; SpotRM Plug-in for StarDrop; Introduction to StarDrop; Optibrium and BioPharmics Enter Partnership on

DRUG CONSTELLATIONS

Drug Constellations. Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all marketed drugs. A summary of key data is provided for each compound, along with an

assessment of its

REACTION-BASED LIBRARY ENUMERATION WEBINAR This webinar was presented by Matt Segall, Peter Hunt and Imants Zudans. In this webinar, we demonstrated how to generate virtual libraries by applying tractable, robust chemical reactions to readily available building blocks in a highly flexible and user-friendly environment.. We were joined by Imants Zudans, CEO of Molport, who described Molport’s compound sourcing services and the

R-GROUP ANALYSIS

R-group Analysis. Jun 1, 2018. StarDrop’s R-group analysis makes it quick and easy to explore the variation of properties by the substituents within a chemical series. This video shows how to perform an R-group decomposition and create SAR plots. The next video in this short series, illustrates how to create information-rich SAR plots.

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Copyright © 2019 Optibrium, Ltd. All Rights Reserved. _Optibrium™, StarDrop™, Augmented Chemistry™, Asteris™, Ocura™, Glowing Molecule™, WhichP450™, Auto-Modeller™, Nova™, MPO Explorer™ and Card View™ are trademarks of Optibrium Ltd. Matsy™ is a trademark of NextMove Software Ltd., BIOSTER™ is a trademark of iKem Szolgáltató és Kereskedelmi BT, Derek Nexus™ is a trademark of Lhasa Ltd., torch3D™ is a trademark of Cresset BioMolecular Discovery Ltd., and SeeSAR™ is a trademark of

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