RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

OUR TECHNOLOGY

The Vevo family of ultra high frequency ultrasound products enables the researcher to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, in real-time and with a resolution down to 30 µm. Our Photoacoustic imaging technology is an in vivo hybrid imaging modality that combines the sensitivity and contrast of optical imaging with the depth and high resolution

ON DEMAND VIDEOS

YouTube. Fujifilm VisualSonics. 449 subscribers. Subscribe. Getting To The Heart Of The Matter: COVID-19 & Other Preclinical Cardiac Disease Models. Watch later. Copy link. Info. Shopping. ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR BRAND PILLARS

Innovation: FUJIFILM VisualSonics has been built on the pillar of Innovation. We originally introduced our Ultra High Frequency technology in the area of preclinical research, specifically in small animal models of human disease (e.g. mice or rat models). This coincided with the explosion of the human genome project (circa 2000),

where numerous

VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. VEVO 3100 | FUJIFILM VISUALSONICS UHF ultrasound with full range of options for advanced preclinical

imaging

VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

MAY 2021: EVALUATION AND OPTIMIZATION OF RIGHT VENTRICULAR Presented by Allison Rodgers, Researcher from the University of Wisconsin, Cardiovascular Research Core Lab, on May 27th, 2021. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

OUR TECHNOLOGY

The Vevo family of ultra high frequency ultrasound products enables the researcher to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, in real-time and with a resolution down to 30 µm. Our Photoacoustic imaging technology is an in vivo hybrid imaging modality that combines the sensitivity and contrast of optical imaging with the depth and high resolution

ON DEMAND VIDEOS

YouTube. Fujifilm VisualSonics. 449 subscribers. Subscribe. Getting To The Heart Of The Matter: COVID-19 & Other Preclinical Cardiac Disease Models. Watch later. Copy link. Info. Shopping. ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR BRAND PILLARS

Innovation: FUJIFILM VisualSonics has been built on the pillar of Innovation. We originally introduced our Ultra High Frequency technology in the area of preclinical research, specifically in small animal models of human disease (e.g. mice or rat models). This coincided with the explosion of the human genome project (circa 2000),

where numerous

VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. VEVO 3100 | FUJIFILM VISUALSONICS UHF ultrasound with full range of options for advanced preclinical

imaging

VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

MAY 2021: EVALUATION AND OPTIMIZATION OF RIGHT VENTRICULAR Presented by Allison Rodgers, Researcher from the University of Wisconsin, Cardiovascular Research Core Lab, on May 27th, 2021. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. CAREERS | FUJIFILM VISUALSONICS Careers. FUJIFILM VisualSonics is a rapidly growing biomedical company and the world leader in developing high-resolution Ultra High Frequency ultrasound and Photoacoustic devices. FUJIFILM VisualSonics offers a pleasant and progressive work environment with a competitive benefits package. We support a strong and dedicated team of

individuals

ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020).

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

OUR TECHNOLOGY

The Vevo family of ultra high frequency ultrasound products enables the researcher to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, in real-time and with a resolution down to 30 µm. Our Photoacoustic imaging technology is an in vivo hybrid imaging modality that combines the sensitivity and contrast of optical imaging with the depth and high resolution

ON DEMAND VIDEOS

YouTube. Fujifilm VisualSonics. 449 subscribers. Subscribe. Getting To The Heart Of The Matter: COVID-19 & Other Preclinical Cardiac Disease Models. Watch later. Copy link. Info. Shopping. ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR BRAND PILLARS

Innovation: FUJIFILM VisualSonics has been built on the pillar of Innovation. We originally introduced our Ultra High Frequency technology in the area of preclinical research, specifically in small animal models of human disease (e.g. mice or rat models). This coincided with the explosion of the human genome project (circa 2000),

where numerous

VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. VEVO 3100 | FUJIFILM VISUALSONICS UHF ultrasound with full range of options for advanced preclinical

imaging

VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

MAY 2021: EVALUATION AND OPTIMIZATION OF RIGHT VENTRICULAR Presented by Allison Rodgers, Researcher from the University of Wisconsin, Cardiovascular Research Core Lab, on May 27th, 2021. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020). ANGIOSTAMP 800 NEAR INFRARED FLUORESCENT IMAGING Angiostamp TM 800 is an organic near-infrared (NIR) fluorescent and photoacoustic imaging agent licensed by Optimal Grenoble, a small animal imaging team in France.It is a NIR imaging agent targeting the αvβ3 integrin. The αvβ3 integrin is overexpressed at the surface of activated endothelial cells during angiogenesis and in various types of tumor cells. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ANOTHER DECADE OF PHOTOACOUSTIC IMAGING Photoacoustic imaging - a hybrid biomedical imaging modality finding its way to clinical practices. Although the 27 photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely 28 researched and used for biomedical imaging applications. In this review we focus on the development and progress 29 of the technology in the last decade (2010-2020). ANGIOSTAMP 800 NEAR INFRARED FLUORESCENT IMAGING Angiostamp TM 800 is an organic near-infrared (NIR) fluorescent and photoacoustic imaging agent licensed by Optimal Grenoble, a small animal imaging team in France.It is a NIR imaging agent targeting the αvβ3 integrin. The αvβ3 integrin is overexpressed at the surface of activated endothelial cells during angiogenesis and in various types of tumor cells. ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research. VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally

LV ANALYSIS

LV Analysis. Clinically sourced functional and anatomical cardiovascular measurements in an easy-to-use tool. The manual LV Analysis tool is widely adopted, having been available for well over 10 years across several different generations of Vevo Imaging Systems. Tracing measurements are available in B-Mode, M-Mode, and EKV Mode. VEVO 3100 | FUJIFILM VISUALSONICS UHF ultrasound with full range of options for advanced preclinical

imaging

MAY 2021: EVALUATION AND OPTIMIZATION OF RIGHT VENTRICULAR Presented by Allison Rodgers, Researcher from the University of Wisconsin, Cardiovascular Research Core Lab, on May 27th, 2021. CONSTRUCTION OF SMART NANOTHERANOSTIC PLATFORM BI-AG@PVP High-efficiency nanotheranostic agents with multimodal imaging guidance have attracted considerable interest in the field of cancer therapy. Herein, novel silver-decorated bismuth-based heterostructured polyvinyl pyrrolidone nanoparticles (NPs) with good biocompatibility (Bi-Ag@PVP NPs) were synthesized for accurate theranostic treatment, which can integrate computed tomography (CT VEVO 2100 LINEAR IMAGING The Vevo® 2100 system expands the functionality, flexibility and image quality of the earlier Vevo 770 system. The Vevo 2100 operates at frequencies never before achieved with solid-state array transducers. The new MicroScan™ transducers provide increased frame rates, superb contrast, unrivaled resolution and a wider field of

view.

GAI-BIASED APELIN ANALOG PROTECTS AGAINST ISOPROTERENOL Apelin receptor (APJ) activation by apelin-13 (APLN-13) engages both Gai proteins and b-arrestins, stimulating distinct intracellular pathways and triggering physiological responses like enhanced cardiac contractility. Substituting the C-terminal phenylalanine of APLN-13 with a-methyl-L-phenylalanine or p-benzoyl-L-phenylalanine (Bpa) generates biased analogs inducing APJ A METAL PROTOPORPHYRIN-INDUCED NANO-SELF-ASSEMBLY FOR Nanomaterial-mediated low-temperature photothermal therapy (PTT) by integrating photothermal agent and heat shock proteins (HSPs) inhibitor holds great potential application in antitumor treatment. A nanoplatform performing improved therapeutic effect that constructed at large scale with green synthesis, high drug loading efficiency, high drug loading capacity, and low cost is highly desired. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally ULTRASOUND LOCALIZATION MICROSCOPY June 04, 2021 Fast super-resolution ultrasound microvessel imaging using spatiotemporal data with deep fully convolutional neural network Ultrasound localization microscopy A METAL PROTOPORPHYRIN-INDUCED NANO-SELF-ASSEMBLY FOR Nanomaterial-mediated low-temperature photothermal therapy (PTT) by integrating photothermal agent and heat shock proteins (HSPs) inhibitor holds great potential application in antitumor treatment. A nanoplatform performing improved therapeutic effect that constructed at large scale with green synthesis, high drug loading efficiency, high drug loading capacity, and low cost is highly desired. A PEGYLATED FLAVIN ADENINE DINUCLEOTIDE PEG COMPLEX TO Flavin adenine dinucleotide (FAD) is engaged in several metabolic diseases. Its main role is being a cofactor essential for the activity of many flavoproteins, which play a crucial role in electron transport pathways in living systems. The aim of this study was to apply a pegylated flavins formulation named FAD-PEG diacide complex as theranostic pathway in cancer therapy. GAI-BIASED APELIN ANALOG PROTECTS AGAINST ISOPROTERENOL Apelin receptor (APJ) activation by apelin-13 (APLN-13) engages both Gai proteins and b-arrestins, stimulating distinct intracellular pathways and triggering physiological responses like enhanced cardiac contractility. Substituting the C-terminal phenylalanine of APLN-13 with a-methyl-L-phenylalanine or p-benzoyl-L-phenylalanine (Bpa) generates biased analogs inducing APJ TRANSMUCOSAL DELIVERY OF SELF-ASSEMBLING PHOTOSENSITIZER Theoretically, on account of improved local bioavailability of photosensitizers and attenuated systemic phototoxicity, intravesical instillation-based photodynamic therapy (PDT) for bladder cancer (BCa) would demonstrate significant advantages in comparison with the intravenous route. Actually, the low transmucosal efficiency, hypoxia regulation deficiency, as well as the biosafety risks of OXYGEN AND OXALIPLATIN-LOADED NANOPARTICLES COMBINED WITH Immunotherapy by stimulating the host immune system has been a promising therapeutic strategy for advanced ovarian cancer. Here we describe a treatment strategy that combines chemotherapy and photo-sonodynamic therapy (PSDT) to induce systemic antitumor immunity. We have successfully fabricated phase-changeable core-shell nanoparticles (OIX_NPs), which carry oxygen in the core and TENDONS ARE RELATIVELY HYPOVASCULAR BUT October 20, 2020 Modulation of vascular response after injury in the rat Achilles tendon alters healing capacity Tendons are relatively

hypovascular but

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

ULTRASOUND IMAGE GALLERY Browse our image gallery showcasing current advances and techniques in ultrasound for research.

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO MD HIGH FREQUENCY ULTRASOUND Ultra High Frequency means the highest resolution medical ultrasound available today. This groundbreaking development opens up new possibilities for medical imaging that have never been seen before with resolution as fine as less than half a grain of sand. Custom-designed and optimized to operate with the Vevo MD are the new UHF Series transducers. VEVO 1100 CARDIOVASCULAR RESEARCH ULTRASOUND The Vevo® 1100 Imaging System is VisualSonics' entry-level ultra high-frequency ultrasound system designed to perform basic cardiovascular studies and to meet both your research and budgetary needs. The Vevo 1100 offers real-time, in vivo physiological information that contributes to understanding the function of the

heart.

VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. VEVO LAZR MULTIMODAL IMAGING The Vevo LAZR system is a versatile multi-modality imaging platform based on the Vevo 2100 which combines high resolution anatomical visualization with functional data such as oxygen saturation, hemodynamics and biomarker microdistribution. This fast, non-invasive, real-time modality is perfect for small animal imaging where pathologies and response to treatment can be monitored longitudinally

ANATOMICAL M-MODE

AM-Mode has been improved by the "fully digital” offering of high temporal resolution. Thus, AM analysis can be performed in any direction, as a uni-dimensional echocardiogram. With respect to traditional M-mode, AM permits a more detailed, flexible analysis of

cardiac chambers.

OUR BRAND PILLARS

Innovation: FUJIFILM VisualSonics has been built on the pillar of Innovation. We originally introduced our Ultra High Frequency technology in the area of preclinical research, specifically in small animal models of human disease (e.g. mice or rat models). This coincided with the explosion of the human genome project (circa 2000),

where numerous

HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons. WHAT IS PHOTOACOUSTIC IMAGING Photoacoustics (or PA) explained. Photoacoustic imaging allows the delivery of light energy that is absorbed by tissues causing a thermoelastic expansion. This expansion then generates ultrasound waves that are detected by the transducer and produce images of optical absorption contrast within tissues. See infographic. VEVO STRAIN SOFTWARE Simply stated, strain is deformation (i.e. a change in length) that occurs when a force is applied. Strain is a complex derivative of Doppler imaging and is a more direct measurement of intrinsic myocardial contractility than global values such as ejection fraction or fractional shortening. VEVO 3100 | FUJIFILM VISUALSONICS UHF ultrasound with full range of options for advanced preclinical

imaging

ULTRASOUND LOCALIZATION MICROSCOPY June 04, 2021 Fast super-resolution ultrasound microvessel imaging using spatiotemporal data with deep fully convolutional neural network Ultrasound localization microscopy A PEGYLATED FLAVIN ADENINE DINUCLEOTIDE PEG COMPLEX TO Flavin adenine dinucleotide (FAD) is engaged in several metabolic diseases. Its main role is being a cofactor essential for the activity of many flavoproteins, which play a crucial role in electron transport pathways in living systems. The aim of this study was to apply a pegylated flavins formulation named FAD-PEG diacide complex as theranostic pathway in cancer therapy. GAI-BIASED APELIN ANALOG PROTECTS AGAINST ISOPROTERENOL Apelin receptor (APJ) activation by apelin-13 (APLN-13) engages both Gai proteins and b-arrestins, stimulating distinct intracellular pathways and triggering physiological responses like enhanced cardiac contractility. Substituting the C-terminal phenylalanine of APLN-13 with a-methyl-L-phenylalanine or p-benzoyl-L-phenylalanine (Bpa) generates biased analogs inducing APJ APPLICATIONS OF THE CHICK CHORIOALLANTOIC MEMBRANE AS AN A variety of in vivo experimental models have been established for the studies of human cancer using both cancer cell lines and patient-derived xenografts (PDXs). In order to meet the aspiration of precision medicine, the in vivomurine models have been widely adopted. However, common constraints such as high cost, long duration of experiments, and low engraftment efficiency remained to be RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. LOG IN | FUJIFILM VISUALSONICS Register. Receive access to exclusive resources for customers only, including software updates, manuals, technical specifications, imaging guides and so much more! Registration is HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health.

TECHNICAL SUPPORT

Technical Support. VisualSonics provides worldwide technical support and repairs to customers. Our highly trained technicians will ensure that any issues are either resolved before leaving the facility or that parts are in the process of being ordered with a scheduled return

visit. Product.

TRANSDUCERS FOR VEVO LAZR FUJIFILM VisualSonics’ LZ Series Transducers combine proven high-frequency ultrasound imaging technology with an integrated fiber optic cable for high-energy laser light delivery. The tight integration and small footprint of these probes provide a flexible platform for photoacoustic imaging of nearly any small animal anatomical area of interest. TRANSMUCOSAL DELIVERY OF SELF-ASSEMBLING PHOTOSENSITIZER Theoretically, on account of improved local bioavailability of photosensitizers and attenuated systemic phototoxicity, intravesical instillation-based photodynamic therapy (PDT) for bladder cancer (BCa) would demonstrate significant advantages in comparison with the intravenous route. Actually, the low transmucosal efficiency, hypoxia regulation deficiency, as well as the biosafety risks of CHEMOTHERAPY-INDUCED ACUTE VASCULAR INJURY INVOLVES Several categories of chemotherapy confer substantial risk for late-term vascular morbidity and mortality. In the present study, we aimed to investigate the mechanism of acute chemotherapy-induced vascular injury in normal tissues. Specifically, we looked at activation of the acid sphingomyelinase (ASMase)/ceramide pathway, which leads to generation of reactive oxygen species (ROS) and OXYGEN AND OXALIPLATIN-LOADED NANOPARTICLES COMBINED WITH Immunotherapy by stimulating the host immune system has been a promising therapeutic strategy for advanced ovarian cancer. Here we describe a treatment strategy that combines chemotherapy and photo-sonodynamic therapy (PSDT) to induce systemic antitumor immunity. We have successfully fabricated phase-changeable core-shell nanoparticles (OIX_NPs), which carry oxygen in the core and SEQUENTIAL RELEASE OF POOLED SIRNAS AND PACLITAXEL BY Paclitaxel (PTX) is a first-line chemotherapeutic agent to treat prostate cancer (PCa), but a large number of patients acquired drug resistance after short-term treatment. To develop combinational therapeutics to overcome PTX-resistant PCa, we established PTX-resistant LNCaP (LNCaP/PTX) cells and found that the LNCaP/PTX cells exhibited epithelial-mesenchymal transition (EMT) and enhanced MEASUREMENT OF TOTAL LIVER BLOOD FLOW IN INTACT This short report describes the measurement of total liver blood flow in commonly used laboratory rats using the relatively non-invasive approach of ultrasound imaging. A total of 29 rats (n = 26 Wistar-Han, n = 3 Sprague–Dawley) were imaged and both male and female rats were included. The mean (SD) total liver blood flow of all animals combined was 33.3 ± 7.8 mL/min, or 104.3 ± 17.1 mL PH-TRIGGERED POLY(ETHYLENE GLYCOL)-POLY(LACTIC ACID The most advantageous and attractive property of photoacoustic imaging is its capability to visualize and differentiate multiple species according to their unique absorbance profiles simultaneously in a single mixture. We here report the pH-sensitive near-infrared (NIR) croconaine (Croc) dyes-loaded copolymeric PEG-PLGA nanoparticles (NPs) for in vivo multiplexed PA imaging and pH-responsive RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. LOG IN | FUJIFILM VISUALSONICS Register. Receive access to exclusive resources for customers only, including software updates, manuals, technical specifications, imaging guides and so much more! Registration is HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health.

TECHNICAL SUPPORT

Technical Support. VisualSonics provides worldwide technical support and repairs to customers. Our highly trained technicians will ensure that any issues are either resolved before leaving the facility or that parts are in the process of being ordered with a scheduled return

visit. Product.

TRANSDUCERS FOR VEVO LAZR FUJIFILM VisualSonics’ LZ Series Transducers combine proven high-frequency ultrasound imaging technology with an integrated fiber optic cable for high-energy laser light delivery. The tight integration and small footprint of these probes provide a flexible platform for photoacoustic imaging of nearly any small animal anatomical area of interest. TRANSMUCOSAL DELIVERY OF SELF-ASSEMBLING PHOTOSENSITIZER Theoretically, on account of improved local bioavailability of photosensitizers and attenuated systemic phototoxicity, intravesical instillation-based photodynamic therapy (PDT) for bladder cancer (BCa) would demonstrate significant advantages in comparison with the intravenous route. Actually, the low transmucosal efficiency, hypoxia regulation deficiency, as well as the biosafety risks of OXYGEN AND OXALIPLATIN-LOADED NANOPARTICLES COMBINED WITH Immunotherapy by stimulating the host immune system has been a promising therapeutic strategy for advanced ovarian cancer. Here we describe a treatment strategy that combines chemotherapy and photo-sonodynamic therapy (PSDT) to induce systemic antitumor immunity. We have successfully fabricated phase-changeable core-shell nanoparticles (OIX_NPs), which carry oxygen in the core and SEQUENTIAL RELEASE OF POOLED SIRNAS AND PACLITAXEL BY Paclitaxel (PTX) is a first-line chemotherapeutic agent to treat prostate cancer (PCa), but a large number of patients acquired drug resistance after short-term treatment. To develop combinational therapeutics to overcome PTX-resistant PCa, we established PTX-resistant LNCaP (LNCaP/PTX) cells and found that the LNCaP/PTX cells exhibited epithelial-mesenchymal transition (EMT) and enhanced PH-TRIGGERED POLY(ETHYLENE GLYCOL)-POLY(LACTIC ACID The most advantageous and attractive property of photoacoustic imaging is its capability to visualize and differentiate multiple species according to their unique absorbance profiles simultaneously in a single mixture. We here report the pH-sensitive near-infrared (NIR) croconaine (Croc) dyes-loaded copolymeric PEG-PLGA nanoparticles (NPs) for in vivo multiplexed PA imaging and pH-responsive MEASUREMENT OF TOTAL LIVER BLOOD FLOW IN INTACT This short report describes the measurement of total liver blood flow in commonly used laboratory rats using the relatively non-invasive approach of ultrasound imaging. A total of 29 rats (n = 26 Wistar-Han, n = 3 Sprague–Dawley) were imaged and both male and female rats were included. The mean (SD) total liver blood flow of all animals combined was 33.3 ± 7.8 mL/min, or 104.3 ± 17.1 mL CHEMOTHERAPY-INDUCED ACUTE VASCULAR INJURY INVOLVES Several categories of chemotherapy confer substantial risk for late-term vascular morbidity and mortality. In the present study, we aimed to investigate the mechanism of acute chemotherapy-induced vascular injury in normal tissues. Specifically, we looked at activation of the acid sphingomyelinase (ASMase)/ceramide pathway, which leads to generation of reactive oxygen species (ROS) and RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. RESEARCH ULTRASOUND LEADER Wednesday, May 26, 2021 11:00 AM (EDT) Evaluation and Optimization of Right Ventricular and Lung Imaging using High Frequency Ultrasound presented by Allison Rodgers, Researcher at the University of Wisconsin. Register here. ABOUT | FUJIFILM VISUALSONICS FUJIFILM VisualSonics specifically focuses on developing ultrasound technology that has been scaled to much higher frequencies than commonly found in many of the conventional ultrasound systems on the market today. As a result, our ultrasound platform provides images at resolutions that far exceed any other system available on the market;

as

OUR PURPOSE

Our Purpose Statement really captures the essence of the passion within all of us at FUJIFILM VisualSonics and motivates us to be the best we can be. Bold innovation is what has brought us success up until today and and it is bold innovation that will ensure our success moving into the future. We thrive on empowering those dedicated to the HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health. ULTRASOUND ANALYSIS SOFTWARE FOR IMAGE DATA Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Vevo LAB allows you to efficiently and easily analyze all of your imaging data with your personal or lab computer. VEVO 3100 PRECLINICAL IMAGING SYSTEM Compact, maneuverable system. Hands-free scanning using Vevo Voice. State-of-the-art Ultra High Frequency - up to 70 MHz. Photoacoustic imaging using the LAZR-X cart. Resolution down to 30 µm. The unique, gesture-driven user interface can be personalized by each user and is easily controlled with the glide of a finger - no keys or buttons.

VEVO CQ SOFTWARE

Vevo CQ Software. Vevo CQ Software allows advanced quantification of perfusion kinetics with consistent and reliable data. Vevo CQ is a powerful addition to Nonlinear Contrast imaging functionality on the Vevo imaging platforms. This software allows you to study contrast uptake kinetics as well as late phase targeted enhancement. SHVM 2020 - POSTPONED UNTIL 2021 SHVM 2020 - POSTPONED UNTIL 2021. Sunday, June 21, 2020 - 1:30pm to Wednesday, June 24, 2020 - 1:30pm. 18th Annual Meeting of the Society for Heart and Vascular Metabolism. We are pleased to invite you to the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax ABDOMINAL IMAGING IN VIVO May 2015 Webinar - Improve Decision Making for Drug Discovery Fujifilm VisualSonics Fujifilm VisualSonics. Preclinical in vivo studies is a critical step in drug development. In vivo imaging in such studies can benefit drug development with rapid and predictive assays to assess drug toxicity and efficacy to reduce clinical attrition rates. VEVO TIPS AND TRICKS Shripad shares: Tips and Tricks for Image Guided Injections. For myocardial or Embryo injections, 5ul is a sufficient volume. One inch 30 gauge needles are always good. These needles are not too rigid and flexible to inject through the body wall and skin. For embryonic injections pulled glass needles are used. LOG IN | FUJIFILM VISUALSONICS Register. Receive access to exclusive resources for customers only, including software updates, manuals, technical specifications, imaging guides and so much more! Registration is HIGH FREQUENCY VASCULAR ULTRASOUND The Vevo MD was designed specifically with vascular applications in mind. Ultra high frequency vascular ultrasound allows for visualization of the smallest vascular anatomy imaginable: arteries and veins in pediatric and neonatal patients. measurement of Intima-Media Thickness (IMT) for research and assessment of cardiovascular health.

TECHNICAL SUPPORT

Technical Support. VisualSonics provides worldwide technical support and repairs to customers. Our highly trained technicians will ensure that any issues are either resolved before leaving the facility or that parts are in the process of being ordered with a scheduled return

visit. Product.

TRANSDUCERS FOR VEVO LAZR FUJIFILM VisualSonics’ LZ Series Transducers combine proven high-frequency ultrasound imaging technology with an integrated fiber optic cable for high-energy laser light delivery. The tight integration and small footprint of these probes provide a flexible platform for photoacoustic imaging of nearly any small animal anatomical area of interest. TRANSMUCOSAL DELIVERY OF SELF-ASSEMBLING PHOTOSENSITIZER Theoretically, on account of improved local bioavailability of photosensitizers and attenuated systemic phototoxicity, intravesical instillation-based photodynamic therapy (PDT) for bladder cancer (BCa) would demonstrate significant advantages in comparison with the intravenous route. Actually, the low transmucosal efficiency, hypoxia regulation deficiency, as well as the biosafety risks of OXYGEN AND OXALIPLATIN-LOADED NANOPARTICLES COMBINED WITH Immunotherapy by stimulating the host immune system has been a promising therapeutic strategy for advanced ovarian cancer. Here we describe a treatment strategy that combines chemotherapy and photo-sonodynamic therapy (PSDT) to induce systemic antitumor immunity. We have successfully fabricated phase-changeable core-shell nanoparticles (OIX_NPs), which carry oxygen in the core and SEQUENTIAL RELEASE OF POOLED SIRNAS AND PACLITAXEL BY Paclitaxel (PTX) is a first-line chemotherapeutic agent to treat prostate cancer (PCa), but a large number of patients acquired drug resistance after short-term treatment. To develop combinational therapeutics to overcome PTX-resistant PCa, we established PTX-resistant LNCaP (LNCaP/PTX) cells and found that the LNCaP/PTX cells exhibited epithelial-mesenchymal transition (EMT) and enhanced PH-TRIGGERED POLY(ETHYLENE GLYCOL)-POLY(LACTIC ACID The most advantageous and attractive property of photoacoustic imaging is its capability to visualize and differentiate multiple species according to their unique absorbance profiles simultaneously in a single mixture. We here report the pH-sensitive near-infrared (NIR) croconaine (Croc) dyes-loaded copolymeric PEG-PLGA nanoparticles (NPs) for in vivo multiplexed PA imaging and pH-responsive MEASUREMENT OF TOTAL LIVER BLOOD FLOW IN INTACT This short report describes the measurement of total liver blood flow in commonly used laboratory rats using the relatively non-invasive approach of ultrasound imaging. A total of 29 rats (n = 26 Wistar-Han, n = 3 Sprague–Dawley) were imaged and both male and female rats were included. The mean (SD) total liver blood flow of all animals combined was 33.3 ± 7.8 mL/min, or 104.3 ± 17.1 mL CHEMOTHERAPY-INDUCED ACUTE VASCULAR INJURY INVOLVES Several categories of chemotherapy confer substantial risk for late-term vascular morbidity and mortality. In the present study, we aimed to investigate the mechanism of acute chemotherapy-induced vascular injury in normal tissues. Specifically, we looked at activation of the acid sphingomyelinase (ASMase)/ceramide pathway, which leads to generation of reactive oxygen species (ROS) and Skip to main content Toggle navigation __

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CALL US AT: 1.866.416.4636 | EUROPE: +800.0751.2020 ALL PRECLINICAL PRODUCTS - VEVO 3100, 2100, 1100, LAZR-X, LAZR, ASSOCIATED TRANSDUCERS, CONTRAST AGENTS AND ACCESSORIES ARE FOR LABORATORY-USE ONLY, NOT FOR HUMAN-USE. VisualSonics, the VisualSonics logo, Vevo, Vevo MicroMarker and EKV are registered and unregistered trademarks of FUJIFILM Sonosite, Inc. in various jurisdictions. FUJIFILM is a registered trademark of FUJIFILM Corporation in various jurisdictions. Copyright © 2021 FUJIFILM Visualsonics, Inc. All rights reserved. FUJIFILM Visualsonics, Inc is a subsidiary of FUJIFILM Sonosite, Inc. FUJIFILM VisualSonics, Inc. 3080 Yonge Street, Suite 6100, Box 66 Toronto, ON, Canada M4N 3N1 WE USE COOKIES ON THIS SITE TO ENHANCE YOUR USER EXPERIENCE By clicking any link on this page you are giving your consent for us

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