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INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

ABOUT THE INSECTICIDE RESISTANCE ACTION COMMITTEE (IRAC) The Insecticide Resistance Action Committee (IRAC) was formed in 1984 and works as a specialist technical group of the industry association CropLife, providing a coordinated industry response to prevent or delay the development of resistance in insect and mite pests.

TRAINING CENTRE

Position papers. IRAC is an authority on insecticide resistance and publishes position papers on key topics affecting food security, for example: Insecticide Resistance Management and the use of mixtures. The combined use of chemicals and traits. Insecticide resistance management for soil and seed applied insecticides. Find a paper. IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are MECHANISMS - INSECTICIDE RESISTANCE ACTION COMMITTEE Behavioural resistance. Resistant insects may detect or recognize a danger and avoid the toxin. This mechanism of resistance has been reported for several classes of insecticides, including organochlorines, organophosphates, carbamates and pyrethroids. Insects may simply stop feeding if they come across certain insecticides, or

leave the area

MODELLING - INSECTICIDE RESISTANCE ACTION COMMITTEE In general insecticide resistance models should be seen as a tool to provide an informed best guess at how insecticide resistance may develop under different insect control scenarios to the best of the modeller and analysists knowledge. Resistance-evolution models have a limited prediction power, but within the boundaries defined in the

model

INSECTICIDE MODE OF ACTION Insecticide Mode of Action - IRAC 67 UPDATED IRM GUIDELINES FOR GROUP 4 INSECTICIDES The use of IRAC Group 4 nicotinic acetylcholine receptor agonists (nAChR) has grown considerably since the introduction of the neonicotinoid insecticide imidacloprid, which was commercialized in 1991. The ten insecticides are classified in four sub-groups 4A-4D. The updated guidelines include a table showing the latest resistance status to the neonicotinoid insecticides. FRANKLINIELLA OCCIDENTALIS Pour 150-ml of test solution into a 200-ml beaker and dip the bean sections using forceps for ca. 30s ensuring complete immersion. After immersion, place the dipped bean sections in a warm dry area on a raised mesh surface to dry. When dry, place the treated bean sections

in

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29) MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers. INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

ABOUT THE INSECTICIDE RESISTANCE ACTION COMMITTEE (IRAC) The Insecticide Resistance Action Committee (IRAC) was formed in 1984 and works as a specialist technical group of the industry association CropLife, providing a coordinated industry response to prevent or delay the development of resistance in insect and mite pests.

TRAINING CENTRE

Position papers. IRAC is an authority on insecticide resistance and publishes position papers on key topics affecting food security, for example: Insecticide Resistance Management and the use of mixtures. The combined use of chemicals and traits. Insecticide resistance management for soil and seed applied insecticides. Find a paper. IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are MECHANISMS - INSECTICIDE RESISTANCE ACTION COMMITTEE Behavioural resistance. Resistant insects may detect or recognize a danger and avoid the toxin. This mechanism of resistance has been reported for several classes of insecticides, including organochlorines, organophosphates, carbamates and pyrethroids. Insects may simply stop feeding if they come across certain insecticides, or

leave the area

MODELLING - INSECTICIDE RESISTANCE ACTION COMMITTEE In general insecticide resistance models should be seen as a tool to provide an informed best guess at how insecticide resistance may develop under different insect control scenarios to the best of the modeller and analysists knowledge. Resistance-evolution models have a limited prediction power, but within the boundaries defined in the

model

INSECTICIDE MODE OF ACTION Insecticide Mode of Action - IRAC 67 UPDATED IRM GUIDELINES FOR GROUP 4 INSECTICIDES The use of IRAC Group 4 nicotinic acetylcholine receptor agonists (nAChR) has grown considerably since the introduction of the neonicotinoid insecticide imidacloprid, which was commercialized in 1991. The ten insecticides are classified in four sub-groups 4A-4D. The updated guidelines include a table showing the latest resistance status to the neonicotinoid insecticides. FRANKLINIELLA OCCIDENTALIS Pour 150-ml of test solution into a 200-ml beaker and dip the bean sections using forceps for ca. 30s ensuring complete immersion. After immersion, place the dipped bean sections in a warm dry area on a raised mesh surface to dry. When dry, place the treated bean sections

in

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29) MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers. INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29)

SPINOSAD | IRAC

Spinosad Mode of Action Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site 1 (5) Chemical Class Spinosyns (5) NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

FALL ARMYWORM DAMAGE SYMPTOMS AND STRATEGIES FOR Fall Armyworm –damage symptoms and Strategies for sustainable control www.irac-online.org Thisposterisforeducationalpurposesonly IRM FOR SUSTAINABLE WHITEFLY CONTROL WITH SPECIAL IRM for sustainable whitefly control with special reference to Bemisia tabaci Insecticide Resistance Action Committee www.irac-online.org This poster is for educational purposes only. INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29)

SPINOSAD | IRAC

Spinosad Mode of Action Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site 1 (5) Chemical Class Spinosyns (5) NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

FALL ARMYWORM DAMAGE SYMPTOMS AND STRATEGIES FOR Fall Armyworm –damage symptoms and Strategies for sustainable control www.irac-online.org Thisposterisforeducationalpurposesonly IRM FOR SUSTAINABLE WHITEFLY CONTROL WITH SPECIAL IRM for sustainable whitefly control with special reference to Bemisia tabaci Insecticide Resistance Action Committee www.irac-online.org This poster is for educational purposes only.

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES A key element of effective resistance management is the use of alternations, rotations, or sequences of different insecticide MoA classes. Users should avoid selecting for resistance or cross-resistance by repeated use within the crop cycle, or year after year, of the same insecticide or related products in the same MoA class. It is important INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see SANDFLY SPECIES ARCHIVES Sandfly species. There are 700 species of sandflies and about 10 percent of these species are known to transmit diseases to people. Sandflies are found mainly in tropical locations, but some species can be found in more temperate regions of the world. Female sandflies suck blood from mammals – including humans – and transmit the disease FRANKLINIELLA OCCIDENTALIS Pour 150-ml of test solution into a 200-ml beaker and dip the bean sections using forceps for ca. 30s ensuring complete immersion. After immersion, place the dipped bean sections in a warm dry area on a raised mesh surface to dry. When dry, place the treated bean sections

in

MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers. INSECTICIDE MODE OF ACTION CLASSIFICATION Insecticide Mode of Action Classification: A Key to Effective Insecticide Resistance Management in Mosquitoes Introduction and

background

JAPAN ARCHIVES

Overview: J IRAC is abbreviated name for Japan Insecticide Resistance Action Committee, and the Japanese translation is “殺虫剤抵抗性対策委員会 INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. IRAC GUIDELINES FOR MANAGEMENT OF RESISTANCE TO GROUP 4 Group!4!Insecticide!resistance!management!guidelines,2nd!edition!!!!!©IRAC2014!www.irac>online.org!! Insecticide Resistance Action Committee www.irac-online.org ! IRAC Guidelines for Management of Resistance to Group 4 insecticides IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29) NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

SPINOSAD | IRAC

Spinosad Mode of Action Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site 1 (5) Chemical Class Spinosyns (5) INSECTICIDE MODE OF ACTION CLASSIFICATION Insecticide Mode of Action Classification: A Key to Effective Insecticide Resistance Management in Mosquitoes Introduction and

background

IRM FOR SUSTAINABLE WHITEFLY CONTROL WITH SPECIAL IRM for sustainable whitefly control with special reference to Bemisia tabaci Insecticide Resistance Action Committee www.irac-online.org This poster is for educational purposes only. INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. IRAC GUIDELINES FOR MANAGEMENT OF RESISTANCE TO GROUP 4 Group!4!Insecticide!resistance!management!guidelines,2nd!edition!!!!!©IRAC2014!www.irac>online.org!! Insecticide Resistance Action Committee www.irac-online.org ! IRAC Guidelines for Management of Resistance to Group 4 insecticides IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29) NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

SPINOSAD | IRAC

Spinosad Mode of Action Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site 1 (5) Chemical Class Spinosyns (5) INSECTICIDE MODE OF ACTION CLASSIFICATION Insecticide Mode of Action Classification: A Key to Effective Insecticide Resistance Management in Mosquitoes Introduction and

background

IRM FOR SUSTAINABLE WHITEFLY CONTROL WITH SPECIAL IRM for sustainable whitefly control with special reference to Bemisia tabaci Insecticide Resistance Action Committee www.irac-online.org This poster is for educational purposes only.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES A key element of effective resistance management is the use of alternations, rotations, or sequences of different insecticide MoA classes. Users should avoid selecting for resistance or cross-resistance by repeated use within the crop cycle, or year after year, of the same insecticide or related products in the same MoA class. It is important IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are MODE OF ACTION CLASSIFICATION 3 Sodium channel modulators See footnotes for further information on use of compounds between sub-groups. 3A Pyrethroids Pyrethrins Acrinathrin, Allethrin, d-cis-trans Allethrin, d-trans Allethrin, Bifenthrin,Bioallethrin, Bioallethrin S-cylclopentenyl, Bioresmethrin,

Cycloprothrin,

IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see SANDFLY SPECIES ARCHIVES Sandfly species. There are 700 species of sandflies and about 10 percent of these species are known to transmit diseases to people. Sandflies are found mainly in tropical locations, but some species can be found in more temperate regions of the world. Female sandflies suck blood from mammals – including humans – and transmit the disease MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers.

BUPROFEZIN | IRAC

Subscribe here. Subscribe to the IRAC eConnection to receive our latest news in your inbox. Your Name. Your Email

ETOFENPROX | IRAC

Etofenprox Mode of Action Sodium channel modulators (3) Chemical Class Pyrethroids-Pyrethrins (3A) INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers. NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

JAPAN ARCHIVES

Overview: J IRAC is abbreviated name for Japan Insecticide Resistance Action Committee, and the Japanese translation is “殺虫剤抵抗性対策委員会 INSECTICIDE RESISTANCE ACTION COMMITTEE The Role of IRAC. IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

TEST METHODS

The availability of standard, validated and easy-to-run methods for resistance detection in the world’s major insect pests is crucial for successful monitoring of resistance problems. Shown below are the IRAC Approved Test Methods which have been validated by IRAC member companies and collaborators to ensure that they provide reliable and reproducible data. Most tests are specific to MODE OF ACTION CLASSIFICATION The definitive, global scheme on the target sites of acaricides and insecticides. The IRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of acaricides or insecticides for use in an effective and sustainable acaricide or insecticide resistance management (IRM) strategy. INTERACTIVE MOA CLASSIFICATION Bind to and disrupt the gating of Nan-Iav TRPV (Transient Receptor Potential Vanilloid) channel complexes in chrodotonal stretch receptor organs, which are critical for the senses of hearing, gravity, balance, acceleration, proprioception and kinesthesia. This IRAC MODE OF ACTION CLASSIFICATION SCHEME IRAC MoA Classification Version: 9.4 Page 3 of 30 Further information is available at: www.irac-online.org or enquiries@irac-online.org 1. Scope The IRAC classification is intended to cover all materials, chemical, biological or other, that are IRAC NEMATICIDE MOA CLASSIFICATION NOW AVAILABLE IRAC Nematicide MoA Classification now available. The IRAC Nematode Working Group is the most recently established IRAC team. The initial objectives of the team were to investigate the resistance risk of nematicides and to develop a mode of action classification scheme similar to that available for insecticides and acaricides. INSECTICIDE RESISTANCE ACTION COMMITTEE MODE OF ACTION Group UN: Compounds of unknown or uncertain mode of action 12B 12C Propargite 12D Tetradifon Organotin miticides Diafenthiuron Azocyclotin Cyhexatin MEGALUROTHRIPS SJOSTEDTI ARCHIVES Megalurothrips sjostedti. The cowpea flower thrips or African bean flower thrips are shiny, black, slender, small-winged insects that feed on flower buds and flowers. During the pre-flowering period, nymphs and adults may damage the terminal buds. However, the main damage is on the flower buds and flowers. NEMATODE WORKING GROUP NEMATICIDE MODE OF ACTION Nerve and muscle (Carbamates, Organophosphates and Avermectins) Pyridinylmethyl-benzamides Tetronic and Tetramic acid derivatives

Unknown Biologicals

JAPAN ARCHIVES

Overview: J IRAC is abbreviated name for Japan Insecticide Resistance Action Committee, and the Japanese translation is “殺虫剤抵抗性対策委員会 INSECTICIDE RESISTANCE MANAGEMENT STRATEGIES A key element of effective resistance management is the use of alternations, rotations, or sequences of different insecticide MoA classes. Users should avoid selecting for resistance or cross-resistance by repeated use within the crop cycle, or year after year, of the same insecticide or related products in the same MoA class. It is important

LEPIDOPTERA

Lepidoptera is an order of insects that includes butterflies and moths. It is one of the most widespread and widely recognizable insect orders in the world. Crop protection companies have developed a broad range of very effective insecticides for the control of lepidopteran pests. Unfortunately, as a consequence of the misuse or overuse of

these

ABOUT THE INSECTICIDE RESISTANCE ACTION COMMITTEE (IRAC) The Insecticide Resistance Action Committee (IRAC) was formed in 1984 and works as a specialist technical group of the industry association CropLife, providing a coordinated industry response to prevent or delay the development of resistance in insect and mite pests. There are IRAC country group committees in many parts of the world

researching

IRAC GUIDELINES FOR MANAGEMENT OF RESISTANCE TO GROUP 4 Group!4!Insecticide!resistance!management!guidelines,2nd!edition!!!!!©IRAC2014!www.irac>online.org!! Insecticide Resistance Action Committee www.irac-online.org ! IRAC Guidelines for Management of Resistance to Group 4 insecticides IRAC GUIDELINES FOR RESISTANCE MANAGEMENT OF NEONICOTINOIDS IRM, Group 28 Insecticides Version: 2.1 Page 3 of 22 Further information is available at: www.irac-online.org or enquiries@irac-online.org Summary IRAC International “Group 28 Working Group” supports the IRAC General Principles of Insecticide Resistance Management (see INSECTICIDE RESISTANCE ACTION COMMITTEE BEST MANAGEMENT 2 Best Management Practices to Control Tuta and Manage Insect Resistance 1. Update Tuta presence and pest status globally 2. Recognize Tuta life stages, life cycle, damage, and plant symptoms CIMEX LECTULARIUS ARCHIVES Cimex lectularius. Body shape: Oval, extremely flattened (dorso-ventral) Length: Unfed up to 6 mm, up to 9 mm after engorgement. Color: Unfed red-brown, dark brown after blood meal. Mouth parts: Biting apparatus (proboscis) with 2 bristles which form a pipe-in-pipe system and is folded under the head and frontal thorax in

resting position.

FLONICAMID | IRAC

Flonicamid Mode of Action Chordotonal Organ Modulators - undefined target site (29) Chemical Class Flonicamid (29)

SPINOSAD | IRAC

Spinosad Mode of Action Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site 1 (5) Chemical Class Spinosyns (5)

JAPAN ARCHIVES

Overview: J IRAC is abbreviated name for Japan Insecticide Resistance Action Committee, and the Japanese translation is “殺虫剤抵抗性対策委員会 We use anonymous data in cookies to understand website usage. You consent to our cookies if you continue to use this website.

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THE ROLE OF IRAC

IRAC is prolonging the effectiveness of insecticides, acaricides and traits by implementing insecticide resistance management strategies, countering the development of resistance in the three core sectors of traditional Crop Protection, Plant Biotechnology and Public Health.

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IRM RESOURCES

Communication and education is key to promoting awareness of insecticide resistance and effective resistance management strategies worldwide. IRAC has published a wide range of communication and educational material, all of which are available free to download from the website. Such communication and educational materials may be used in their entirety and/or portions of such materials may be used freely so long as the appropriate citations are provided for all the applicable authors, materials and/or website. Printed copies of the booklets and the English version of the Mode of Action poster with the structures are available via the IRAC Coordinator.

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RECOMMENDED RESOURCES * MOA Structures Poster (English) Poster showing the IRAC Mode of Action Classification, showing chemical structures for the key actives * The IRAC Mode of Action Classification Online Mode of Action as an online searchable tool with an easy to use search

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* Nematicides MoA Classification IRAC Mode of Action classification for Nematodes listing the Nematicide Groups Numbers, Mode of action type and Chemical Groups * Insecticide Resistance Training – Basic Module A training module designed to introduce the basic concepts behind the development and management of insecticide resistance. * Tutorial on MoA Mechanisms A set of 74 slides explaining with graphics the major mechanisms and targets of insecticide resistance. * IRM for soil & seed applied applied insecticides IRAC International statement on the resistance management considerations of utilizing soil & seed applied insecticides * Lepidoptera IRM Guidelines Insecticide resistance management guidelines for lepidopteran pests. * Sucking Pest IRM Guidelines IRM Guidelines for Sucking Pests (Graphics Version) A GLOBAL RESPONSE TO A GLOBAL PROBLEM Insecticide resistance management is a global challenge, and IRAC is delivering strategic responses worldwide with localized as well as international initiatives. Explore local country groups via the map.

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