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COVID-19 PROTEINS
The SARS-CoV-2 virus in COVID-19 is composed of two main proteins, the nucleocapsid protein (N-protein) and spike protein (S-protein). These proteins are encoded by all coronaviruses. Both recombinant forms of these specific COVID-19 proteins are now available from RayBiotech to advance infectious disease research (Figures 1 & 2).ANTIBODY ARRAYS
Antibody arrays allow a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokinesignaling.
COVID-19 SERUM OR PLASMA SAMPLE Serum or plasma (EDTA) from COVID-19 patients with varying IgM, IgA, and/or IgG antibody levels. COVID-19 status was confirmed with RT-PCR, antigen, and/or antibody serology tests to the SARS-CoV-2 nucleocapsidprotein.
MOUSE INFLAMMATION ARRAY C1 Citations (54) RayBio ® C-Series Mouse Inflammation Antibody Array 1 Kit. Detects 40 Mouse Inflammatory Factors. Suitable for all liquid sample types. $358.55. CODE: AAM-INF-1-2. HUMAN CYTOKINE ARRAY Q640 Product Features. More cost-effective than traditional ELISA. High specificity and system reproducibility. Suitable for diverse sample types. Low sample volume requirement: 800 µL or less. Get results same day (6-hour processing time) Well-suited for high throughputassays.
NRF2 TRANSCRIPTION FACTOR ACTIVITY ASSAY Figure 1 Transcription factor activity assay of NRF2 from nuclear extracts of HepG2 cells or HepG2 cells treated with tBHQ (90uM) for 24 hr. After stimulation activated NRF2 is translocated into the nucleus where it binds with its corresponding DNA. A. Western-blot HUMAN ANTI-RNP AUTO-ANTIGEN Specificity is verified by identity of precipitation with CDC-AF reference serum. The titer obtained will vary with the test system; however, undiluted antibody shows a strong RNP precipitate band in double diffusion. No reactivity at a dilution of 1:100 when tested against purified SSA, SSB, Scl-70, Sm, and Jo-1 antigens in an ELISAsystem
RAYBIOTECH: EMPOWERING YOUR PROTEOMICSRESEARCH TOPICSSERVICESRESOURCESCONTACT USISO 13485:2016GCLP Akt Signaling Pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is READ MORE JAK/STAT Signaling Pathway The JAK/STAT pathway is a principal signaling mechanism for many FIGHTING CORONAVIRUS Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines. For researchers and health professionals needing lab facilities or additional COVID-19 SPIKE-ACE2 BINDING ASSAY KIT COVID-19 Spike-ACE2 Binding Assay Kit. 7 reviews. The RayBio® COVID-19 Spike-ACE2 binding assay kit is a rapid, simple, and sensitive method to characterize the binding affinity of the SARS-CoV-2 Spike (S) protein and the Angiotensin I Converting Enzyme 2 (ACE2) receptor complex in the presence of potential inhibitors. $487.00. CODE: CoV-ACE2S2-1.COVID-19 PROTEINS
The SARS-CoV-2 virus in COVID-19 is composed of two main proteins, the nucleocapsid protein (N-protein) and spike protein (S-protein). These proteins are encoded by all coronaviruses. Both recombinant forms of these specific COVID-19 proteins are now available from RayBiotech to advance infectious disease research (Figures 1 & 2).ANTIBODY ARRAYS
Antibody arrays allow a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokinesignaling.
COVID-19 SERUM OR PLASMA SAMPLE Serum or plasma (EDTA) from COVID-19 patients with varying IgM, IgA, and/or IgG antibody levels. COVID-19 status was confirmed with RT-PCR, antigen, and/or antibody serology tests to the SARS-CoV-2 nucleocapsidprotein.
MOUSE INFLAMMATION ARRAY C1 Citations (54) RayBio ® C-Series Mouse Inflammation Antibody Array 1 Kit. Detects 40 Mouse Inflammatory Factors. Suitable for all liquid sample types. $358.55. CODE: AAM-INF-1-2. HUMAN CYTOKINE ARRAY Q640 Product Features. More cost-effective than traditional ELISA. High specificity and system reproducibility. Suitable for diverse sample types. Low sample volume requirement: 800 µL or less. Get results same day (6-hour processing time) Well-suited for high throughputassays.
NRF2 TRANSCRIPTION FACTOR ACTIVITY ASSAY Figure 1 Transcription factor activity assay of NRF2 from nuclear extracts of HepG2 cells or HepG2 cells treated with tBHQ (90uM) for 24 hr. After stimulation activated NRF2 is translocated into the nucleus where it binds with its corresponding DNA. A. Western-blot HUMAN ANTI-RNP AUTO-ANTIGEN Specificity is verified by identity of precipitation with CDC-AF reference serum. The titer obtained will vary with the test system; however, undiluted antibody shows a strong RNP precipitate band in double diffusion. No reactivity at a dilution of 1:100 when tested against purified SSA, SSB, Scl-70, Sm, and Jo-1 antigens in an ELISAsystem
COVID-19 PROTEINS
The SARS-CoV-2 virus in COVID-19 is composed of two main proteins, the nucleocapsid protein (N-protein) and spike protein (S-protein). These proteins are encoded by all coronaviruses. Both recombinant forms of these specific COVID-19 proteins are now available from RayBiotech to advance infectious disease research (Figures 1 & 2). COVID-19 SERUM OR PLASMA SAMPLE Serum or plasma (EDTA) from COVID-19 patients with varying IgM, IgA, and/or IgG antibody levels. COVID-19 status was confirmed with RT-PCR, antigen, and/or antibody serology tests to the SARS-CoV-2 nucleocapsidprotein.
RT-LAMP COVID-19 RAPID ISOTHERMAL PCR KIT No PCR instrument required! This PCR test kit utilizes the RT-LAMP (reverse transcription loop-mediated isothermal amplification) method for the qualitative detection of SARS-CoV-2 in purified RNA isolated from nasopharyngeal swabs. Results detected by eye or ELISA TESTING SERVICE All RayBio ® ELISA kits are manufactured under FDA's Good Manufacturing Practice (GMP) Regulations and are ISO 13485 certified. With our team of highly experienced scientists in our GLP-compliant laboratory, RayBiotech’s service department provides you SARS-COV-2 (COVID-19) S-PROTEIN S1 RBD ANTIBODY This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein. The IgG fraction was purified by Protein A affinity chromatography. Product is supplied as a powder obtained from lyophilization of purified antibody in 1X PBS, aliquot using ddH2O. Reconstitute the antibody with sterile water to a finalCYTOKINE ARRAY C5
The cytokine array is an antibody based immunoassay similar to ELISA, but able to simultaneously measure multiple proteins on one solid support. The Cytokine Array C5 is a membrane-based antibody array, using a panel of 80 different capture antibodies printed on a nitrocellulose membrane. The protein from the incubated sample iscaptured, and a
SANDWICH ELISA KITS
Sandwich ELISA is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of soluble proteins in biological fluids. RayBiotech sandwich ELISA kits are manufactured in Peachtree Corners, GA, validated with 5 different sample matrices* and backed by a 100% satisfaction guarantee. ERK/JNK/P38? ELISA KIT This Sandwich ELISA kit is an in vitro enzyme-linked immunosorbent assay for the measurement of human, mouse and rat phospho-ERK1/2, total ERK1/2, phospho-JNK, total JNK, phospho- P38α and total P38α. For each target, a capture antibody has been coated onto microwells. Samples are pipetted into the wells and target proteinpresent in a
TROPONIN T ELISA KIT RayBio® Human Troponin T ELISA Kit for cell culture supernatants, plasma, and serum samples. Highly sensitive 96-well immunoassay kit with additional reagents. STAT6 (TYR641) ELISA KIT RayBio® Human Phospho-STAT6 (Tyr641) ELISA Kit. This assay semi-quantitatively measures STAT6 phosphorylated at Tyrosine-641 in lysate samples. $496.00. CODE: PEL-STAT6-Y641-1. Number of Plates: 1 Plate Kit 2 Plate Kit 5 Plate Kit. Quantity: RAYBIOTECH: EMPOWERING YOUR PROTEOMICSRESEARCH TOPICSSERVICESRESOURCESCONTACT USISO 13485:2016GCLP Akt Signaling Pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is READ MORE JAK/STAT Signaling Pathway The JAK/STAT pathway is a principal signaling mechanism for many FIGHTING CORONAVIRUS Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines. For researchers and health professionals needing lab facilities or additionalMAGNETIC BEADS
RayBio ® Magnetic Beads are superparamagnetic, non-aggregating iron oxide particles (or 'microspheres') for sample prep, or for capturing / purifying (SPRI: Solid Phase Reversible Immobilization) targets such as proteins, antibodies, DNA/RNA (direct, or via ChIP, RIP, or CLIP), and E. coli. The bead's design enables faster binding kinetics, with high sensitivity & selectivity, in both manual RAYBIOTECH CERTIFIED SERVICE PROVIDERS The service providers below, indicated by the blue pipette icon have successfully completed RayBiotech’s training and certification program for testing samples with our antibody array products and have been designated as "RayBiotech Certified Array Service Providers", any of which you can trust to give you the same high-quality testingresults you expect.
ANTIBODY ARRAYS
Antibody arrays allow a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokinesignaling.
SANDWICH ELISA KITS
Sandwich ELISA is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of soluble proteins in biological fluids. RayBiotech sandwich ELISA kits are manufactured in Peachtree Corners, GA, validated with 5 different sample matrices* and backed by a 100% satisfaction guarantee. TROPONIN T ELISA KIT RayBio® Human Troponin T ELISA Kit for cell culture supernatants, plasma, and serum samples. Highly sensitive 96-well immunoassay kit with additional reagents. MOUSE IL-15 ELISA KIT RayBio® Mouse IL-15 ELISA Kit for cell culture supernatants, plasma, and serum samples. Highly sensitive 96-well immunoassay kit with additional reagents. NRF2 TRANSCRIPTION FACTOR ACTIVITY ASSAY Figure 1 Transcription factor activity assay of NRF2 from nuclear extracts of HepG2 cells or HepG2 cells treated with tBHQ (90uM) for 24 hr. After stimulation activated NRF2 is translocated into the nucleus where it binds with its corresponding DNA. A. Western-blot HUMAN ANTI-RNP AUTO-ANTIGEN Specificity is verified by identity of precipitation with CDC-AF reference serum. The titer obtained will vary with the test system; however, undiluted antibody shows a strong RNP precipitate band in double diffusion. No reactivity at a dilution of 1:100 when tested against purified SSA, SSB, Scl-70, Sm, and Jo-1 antigens in an ELISAsystem
RAYBIOTECH: EMPOWERING YOUR PROTEOMICSRESEARCH TOPICSSERVICESRESOURCESCONTACT USISO 13485:2016GCLP Akt Signaling Pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is READ MORE JAK/STAT Signaling Pathway The JAK/STAT pathway is a principal signaling mechanism for many FIGHTING CORONAVIRUS Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines. For researchers and health professionals needing lab facilities or additionalMAGNETIC BEADS
RayBio ® Magnetic Beads are superparamagnetic, non-aggregating iron oxide particles (or 'microspheres') for sample prep, or for capturing / purifying (SPRI: Solid Phase Reversible Immobilization) targets such as proteins, antibodies, DNA/RNA (direct, or via ChIP, RIP, or CLIP), and E. coli. The bead's design enables faster binding kinetics, with high sensitivity & selectivity, in both manual RAYBIOTECH CERTIFIED SERVICE PROVIDERS The service providers below, indicated by the blue pipette icon have successfully completed RayBiotech’s training and certification program for testing samples with our antibody array products and have been designated as "RayBiotech Certified Array Service Providers", any of which you can trust to give you the same high-quality testingresults you expect.
ANTIBODY ARRAYS
Antibody arrays allow a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokinesignaling.
SANDWICH ELISA KITS
Sandwich ELISA is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of soluble proteins in biological fluids. RayBiotech sandwich ELISA kits are manufactured in Peachtree Corners, GA, validated with 5 different sample matrices* and backed by a 100% satisfaction guarantee. TROPONIN T ELISA KIT RayBio® Human Troponin T ELISA Kit for cell culture supernatants, plasma, and serum samples. Highly sensitive 96-well immunoassay kit with additional reagents. MOUSE IL-15 ELISA KIT RayBio® Mouse IL-15 ELISA Kit for cell culture supernatants, plasma, and serum samples. Highly sensitive 96-well immunoassay kit with additional reagents. NRF2 TRANSCRIPTION FACTOR ACTIVITY ASSAY Figure 1 Transcription factor activity assay of NRF2 from nuclear extracts of HepG2 cells or HepG2 cells treated with tBHQ (90uM) for 24 hr. After stimulation activated NRF2 is translocated into the nucleus where it binds with its corresponding DNA. A. Western-blot HUMAN ANTI-RNP AUTO-ANTIGEN Specificity is verified by identity of precipitation with CDC-AF reference serum. The titer obtained will vary with the test system; however, undiluted antibody shows a strong RNP precipitate band in double diffusion. No reactivity at a dilution of 1:100 when tested against purified SSA, SSB, Scl-70, Sm, and Jo-1 antigens in an ELISAsystem
ELISA KITS - RAYBIOTECH ELISA kits are enzyme-linked immunosorbent assays designed for the quick detection and quantitation of target proteins, antibodies, and other soluble targets of interest. RayBiotech’s objective is to manufacture a diverse selection of high quality ELISA kits to serve a broad range of research interests. Our target protein selectionincludes a
COVID-19 PROTEINS
The SARS-CoV-2 virus in COVID-19 is composed of two main proteins, the nucleocapsid protein (N-protein) and spike protein (S-protein). These proteins are encoded by all coronaviruses. Both recombinant forms of these specific COVID-19 proteins are now available from RayBiotech to advance infectious disease research (Figures 1 & 2). ELISA TESTING SERVICE All RayBio ® ELISA kits are manufactured under FDA's Good Manufacturing Practice (GMP) Regulations and are ISO 13485 certified. With our team of highly experienced scientists in our GLP-compliant laboratory, RayBiotech’s service department provides youSANDWICH ELISA KITS
Sandwich ELISA is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of soluble proteins in biological fluids. RayBiotech sandwich ELISA kits are manufactured in Peachtree Corners, GA, validated with 5 different sample matrices* and backed by a 100% satisfaction guarantee. AUTO-WESTERN BLOTTING SERVICE RayBiotech’s Auto-Western Service marries our state-of-the-art capillary immunoprobing system with our vast pre-validated antibody library. Our high throughput system can achieve ng to pg sensitivity with only 5 µL of starting material. Just send us your samples, select your desired antibody from our pre-validated list, and we’lldo the rest.
ERK/JNK/P38? ELISA KIT This Sandwich ELISA kit is an in vitro enzyme-linked immunosorbent assay for the measurement of human, mouse and rat phospho-ERK1/2, total ERK1/2, phospho-JNK, total JNK, phospho- P38α and total P38α. For each target, a capture antibody has been coated onto microwells. Samples are pipetted into the wells and target proteinpresent in a
MOUSE INFLAMMATION ARRAY C1 Citations (54) RayBio ® C-Series Mouse Inflammation Antibody Array 1 Kit. Detects 40 Mouse Inflammatory Factors. Suitable for all liquid sample types. $358.55. CODE: AAM-INF-1-2.IFN-GAMMA ELISA KIT
The human IFNg ELISA kit is easy to follow and reproducible. We used the kit with IFNg-secreting human cell lines following the manufacturer's protocol after the cells were treated with LPS. The supernatant was used to detect the IFNg. The kit worked perfectly when detecting high content of IFNg. HUMAN CYTOKINE ARRAY C3 Citations (130) RayBio ® C-Series Human Cytokine Antibody Array 3 Kit. Detects 42 Humans Cytokines. Suitable for all liquid sample types. $440.36. CODE: AAH-CYT-3-2. AKT SIGNALING PATHWAY Akt Signaling Pathway. The phosphatidylinositol 3' -kinase (PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is implicated in a number of disease states including770-729-2992
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Phosphorylation Pathway Profiling Array C55 Detects 55 phosphorylated human proteins in the MAPK, AKT, JAK/STAT, NFkB, and TGFb signaling pathways. Learn More Why Run Your Own Westerns? Leave the burden of validating antibodies and optimizing conditions to us. RayBiotech’s Auto-Western Service marries our state-of-the-art capillary immunoblotting system with our vast pre-validated antibody library, for as little as $30 per sample!LEARN MORE
POSTS, PAPERS, & PUBLICATIONS Aptamers: Applications & Strategies for Development Often described as synthetic antibodies, aptamers are single-stranded DNA or RNA molecules that fold into secondary structures which can bind to target molecules with high affinity and specificity. READ MORE RayBiotech Oncotarget Publication on Reverse Phase Protein Arrays A publication in Ocontarget, 2018 from RayBiotech scientists explaining the benefits of RPPAs as a quantitative high-throughput platform. "Quantitative screening of serum protein biomarkers by reverse phase protein arrays" READ MORE Biostatistics & Bioinformatics In the biology field, we often ask: how does this sample group compare to another sample group? Biostatisticians love the math, but most of us simply want to understand the basic principles behind these analyses. In this blog post, we provide a general understanding of common biostatistical methods used to analyze data. READ MORE INTERACTIVE PATHWAY MAPS Akt Signaling Pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is… READ MORE JAK/STAT Signaling Pathway The JAK/STAT pathway is a principal signaling mechanism for many cytokines and growth factors and provides a direct mechanism to translate extracellular signals into transcriptional responses. Activation of this pathway stimulates cell proliferation, differentiation… READ MORE Notch Signaling Pathway The Notch signaling pathway is a highly conserved system present in many multicellular organisms. Mammals are known to express four different notch receptors, called Notch1, Notch2, Notch3, and Notch4. Notch signaling is crucial in a wide array of developmental processes… READ MORE NF-KappaB Signaling Pathway The nuclear factor-κB (NF-κB)/Rel family members function as dimeric transcription factors that play important roles in regulating the expression of cytokines, growth factors, and inhibitors of apoptosis. Two signaling pathways lead to the activation of NF-κB, known as the… READ MORE AMPK Signaling Pathway AMP-activated protein kinase (AMPK) is a central regulator of cellular energy homeostasis, playing critical roles in regulating growth and reprogramming metabolism as well as in cellular processes including autophagy and cell polarity. The kinase is activated in response to… READ MORE Hedgehog Signaling Pathway Hedgehog is an evolutionarily conserved pathway which initiates a range of cellular responses including proliferation, differentiation, survival and cell fate decisions. The human homolog, Sonic hedgehog (Shh) is a diffusible morphogen which directs development, maintenance… READ MORE MAPK Signaling Pathway The mitogen-activated protein kinase (MAPK) signaling pathway is activated by a number of extra and intracellular stimuli including cytokines, growth factors, and hormones as well as stressors such as oxidative and ER stress. This pathway plays a key role in the regulation… READ MORE TGF-beta Signaling Pathway Transforming growth factor-β (TGF-β) signaling plays a key role tissue homeostasis, which is accomplished through dynamic regulation of many cellular processes, including cell growth, migration, differentiation, epithelial-mesenchymal transition, and extracellular matrix… READ MORE__
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SOME OF OUR CUSTOMERS WHAT OUR CUSTOMERS ARE SAYING __The ELISA kit for Human Albumin is simply fantastic and easy to use. The procedure is very quick and gives you great and reliable results. Super recommended.____________
Giuseppe
__Highly informative setup that answers many initial questions and provides insights on future directions. The protocol is easy to follow and not very time consuming. The final results came out clear with high degree of reproducibility. Very low background and great signal to noise ratio. On the less positive side I would mention high cost of the kit. But given the fact the kit provides a great amount of data one might consider the price factor as worthwhile. ____________
Rony
__Very robust kit . My standards came out to be crisp and duplicates had low %CV. Very satisfied and confident about mydata.__
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Nivedita
__It is the only ELISA Array that gives a quantified assessment of 25 chemokines in one go. Protocol is easy to follow and with RayBiotech providing free scanning of slides, it is the best chemokine ELISA Array available.____________
Shalini, NIH
__The Phospho-PTEN (S380) / total PTEN ELISA is easy to use and gave clean and accurate results!__________
Michelle, University at Buffalo __I used this plate several times along with other similar ELISA kits from different suppliers. I would definitely say that this kit gave me the strongest data. The instructions were also easy to read and I found the whole procedure to be very simple. ____________
Isa, MGH
__Kelly is amazingly efficient to figure out exact what I need and provide the info to me surprisingly quick. She is extremely knowledgeable about the products and services. I am impressed.____________
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Lenny, The University of Edinburgh __I am very pleased with the customer service and technical support at RayBiotech. I would say one of the best I experienced in recent years.__
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Ramiro, The Ohio State University __I'm always impressed with your quick and kind response. I greatly appreciate your help.____________
__Brianne, Jarad, and Kelly were indeed super supportive with the query. All the tech support team from RayBio is indeed super awesome! They are my favorite tech support team across all the other vendors we work with. SAVIORS!! Good going team.____________
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