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PRODUCTS - MIMETAS
OrganoReady ® Caco‑2. OrganoReady ® Caco-2 offers 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. The product is based on an OrganoPlate ® 3-lane 40 with 3 adjacent channels per chip, including one perfused Caco-2 tubule. Moreinformation.
ORGANOTEER®
OrganoTEER: how it works. Perform OrganoTEER ® measurements By characterizing tubular models with OrganoTEER ® measurements, you can perform exposure studies to evaluate cytotoxicity and inflammatory reaction to compounds over minutes, hours, and days. You will be able to do timelapse series in the incubator and under flow conditions.ORGANOPLATE® GRAFT
OrganoPlate ® Graft is the first in vitro tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues. OrganoPlate® Graft features: Each chip contains one in-gel culture channel, two perfusion channels, and one open grafting chamber.ORGANOFLOW®
OrganoFlow ® drives precisely-controlled perfusion flow. in the OrganoPlate ® platform. OrganoFlow features: Optimal control of perfusion flow in OrganoPlates. Pump- and tube-free perfusion of your cultures. Optimized time- and tilting angle settings, including interval rocking. Suitable for use in standard tissue cultureincubators.
3D CELL CULTURE VS. TRADITIONAL 2D CELL CULTURE EXPLAINED 2D vs. 3D Cell Culture. Simple, inexpensive, and reproducible, traditional or 2D cell culture is the mainstay of biological research. Meanwhile, 3D cell culture systems feature increased complexity for increased faithfulness to the in vivo environment. The primary changes to cells in 3D are rather obvious – shape, motility, and polarityare
ORGANOPLATE® 2-LANE 96 OrganoPlate® 2-lane features: 96 independent tissue culture chips. 2 adjacent channels per chip. Direct access to apical lumen of tubular cultures. Each chip contains one in-gel culture channel and one perfusion channel. This enables the culture of perfused tubules adjacent to an extracellular matrix (ECM) of choice without artificialmembranes.
ANGIOGENESIS IN THE ORGANOPLATE® 3-LANE 2 Version 2.2 www.mimetas.com | info@mimetas.com | +31 85 888 3161 Angiogenesis in the OrganoPlate® 3-lane . 2. Prepare the stock solutions of the six angiogenic compounds as described in column 4 oftable 1.
ENHANCED PATIENT-SPECIFIC INTESTINE-ON-A-CHIP MODEL FOR The OrganoPlate ® was developed to fill this gap and provides a robust, flexible platform that is amenable to drug screening. Recent adaptations 1,2 of a previously established intestine-on-a-chip model3 has paved the way for new opportunities in high-throughput drug discovery and research related to intestinal inflammation. ORGAN-ON-A-CHIP WORKSHOP JAPAN For the workshop in Europe, click here. For the workshop in the USA, click here. For industry workshops, send us a message. HUMAN TISSUE MODELS FOR BETTER THERAPIES MIMETAS offers OrganoPlates and develops human tissue and disease models for tomorrow’s medicines, chemicals and food. Kickstart now your experiments with the most sophisticated 3D tissue culture platform or work with us to develop amazing 3D tissue and dPRODUCTS - MIMETAS
OrganoReady ® Caco‑2. OrganoReady ® Caco-2 offers 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. The product is based on an OrganoPlate ® 3-lane 40 with 3 adjacent channels per chip, including one perfused Caco-2 tubule. Moreinformation.
ORGANOTEER®
OrganoTEER: how it works. Perform OrganoTEER ® measurements By characterizing tubular models with OrganoTEER ® measurements, you can perform exposure studies to evaluate cytotoxicity and inflammatory reaction to compounds over minutes, hours, and days. You will be able to do timelapse series in the incubator and under flow conditions.ORGANOPLATE® GRAFT
OrganoPlate ® Graft is the first in vitro tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues. OrganoPlate® Graft features: Each chip contains one in-gel culture channel, two perfusion channels, and one open grafting chamber.ORGANOFLOW®
OrganoFlow ® drives precisely-controlled perfusion flow. in the OrganoPlate ® platform. OrganoFlow features: Optimal control of perfusion flow in OrganoPlates. Pump- and tube-free perfusion of your cultures. Optimized time- and tilting angle settings, including interval rocking. Suitable for use in standard tissue cultureincubators.
3D CELL CULTURE VS. TRADITIONAL 2D CELL CULTURE EXPLAINED 2D vs. 3D Cell Culture. Simple, inexpensive, and reproducible, traditional or 2D cell culture is the mainstay of biological research. Meanwhile, 3D cell culture systems feature increased complexity for increased faithfulness to the in vivo environment. The primary changes to cells in 3D are rather obvious – shape, motility, and polarityare
ORGANOPLATE® 2-LANE 96 OrganoPlate® 2-lane features: 96 independent tissue culture chips. 2 adjacent channels per chip. Direct access to apical lumen of tubular cultures. Each chip contains one in-gel culture channel and one perfusion channel. This enables the culture of perfused tubules adjacent to an extracellular matrix (ECM) of choice without artificialmembranes.
ANGIOGENESIS IN THE ORGANOPLATE® 3-LANE 2 Version 2.2 www.mimetas.com | info@mimetas.com | +31 85 888 3161 Angiogenesis in the OrganoPlate® 3-lane . 2. Prepare the stock solutions of the six angiogenic compounds as described in column 4 oftable 1.
ENHANCED PATIENT-SPECIFIC INTESTINE-ON-A-CHIP MODEL FOR The OrganoPlate ® was developed to fill this gap and provides a robust, flexible platform that is amenable to drug screening. Recent adaptations 1,2 of a previously established intestine-on-a-chip model3 has paved the way for new opportunities in high-throughput drug discovery and research related to intestinal inflammation. ORGAN-ON-A-CHIP WORKSHOP JAPAN For the workshop in Europe, click here. For the workshop in the USA, click here. For industry workshops, send us a message.LOCATIONS - MIMETAS
MIMETAS offers OrganoPlates and develops human tissue and disease models for tomorrow’s medicines, chemicals and food. Check the applications, products, or work with us to develop amazing 3D tissueand disease models.
KNOWLEDGE CENTER
Knowledge Center. Get up to speed with 3D tissue culture and learn how OrganoPlate ® supports your research needs. Read publications from customers and our scientists, watch our webinars, or check our application notes, protocols, and brochures. Filter on your topic of ENHANCED PATIENT-SPECIFIC INTESTINE-ON-A-CHIP MODEL FOR The OrganoPlate ® was developed to fill this gap and provides a robust, flexible platform that is amenable to drug screening. Recent adaptations 1,2 of a previously established intestine-on-a-chip model3 has paved the way for new opportunities in high-throughput drug discovery and research related to intestinal inflammation. MPS WORLD SUMMIT: TOWARDS REGULATORY ACCEPTANCE June 24, Virtual Meeting. The MPS (Microphysiological Systems) World Summit will bring together a global audience, including institutions (government, health foundations, charities), the academic research community (universities, research institutes), environmental and human toxicity researchers, the pharmaceutical and other industries (cosmetics, chemical, and food industries), medicalJACQUELIEN TEN DAM
Jacquelien Ten Dam. This interview is part of a series of conversations with the people working at Mimetas. The 'I' in Mimetas focuses on the personal side of the scientists that drive our world. Today we have a chat with Jacquelien ten Dam, who is as CFO responsible for the Corporate Development and Finance activities atMimetas.
THE BEGINNER’S GUIDE TO ECM GELS Agarose - Agarose is the main component of agar and is derived from red algae. It is a linear polysaccharide that dissolves upon heating and gelates when cooled, as intermolecular hydrogen bonds form. Agarose can form gels between 1 to ~1000 kPa in ORGAN-ON-A-CHIP WORKSHOP JAPAN For the workshop in Europe, click here. For the workshop in the USA, click here. For industry workshops, send us a message. 2D VERSUS 3D CELL CULTURES: ADVANTAGES AND DISADVANTAGES Reasons for the increasing acceptance and use of 3D cell cultures include: More relevant cell models — Much better biomimetic tissue models make 3D cell cultures more physiologically relevant and predictive than 2D cultures. 3D plate cultures also show a higher degree of structural complexity and retain a “steady state”(homeostasis) for
7 WAYS CACO-2 CELLS CAN MAKE OR BREAK YOUR INTESTINAL 7 Ways Caco-2 Cells Can Make or Break Your Intestinal Permeability Models. Increased intestinal permeability has been described in a number of diseases, including inflammatory bowel disorders ( IBD) 1, celiac disease2, and in conditions not primarily associated with the intestines. 3 Even though the etiology of these diseases is far fromclear
CASE STUDY: 3D GLOMERULAR FILTRATION BARRIER MODEL A unique model for the screening of drugs targeting the glomerular filtration barrier. Deposition observed of de novo extracellular membrane components that are specific to the glomerulus. The model shows its potential for high-throughput screening of therapeutic compounds. A total of 2000 independent chips, 50 OrganoPlates, wereanalyzed.
HUMAN TISSUE MODELS FOR BETTER THERAPIES MIMETAS offers OrganoPlates and develops human tissue and disease models for tomorrow’s medicines, chemicals and food. Kickstart now your experiments with the most sophisticated 3D tissue culture platform or work with us to develop amazing 3D tissue and dPRODUCTS - MIMETAS
Use OrganoPlate to develop in vitro 3D tissue and disease models. Get inspired by applications, OrganoPlate, and related products to kickstart your experiments.ORGANOTEER®
OrganoTEER: how it works. Perform OrganoTEER ® measurements By characterizing tubular models with OrganoTEER ® measurements, you can perform exposure studies to evaluate cytotoxicity and inflammatory reaction to compounds over minutes, hours, and days. You will be able to do timelapse series in the incubator and under flow conditions.ORGANOPLATE® GRAFT
OrganoPlate ® Graft: how it works. Functional blood vessels are a vital connecting structure inside the body. This aspect is missing in all currently available in vitro cell culture techniques, until now. OrganoPlate ® Graft is developed for grafting tissues to a vascular bed. Its open-top design makes it possible to receive target tissues for studying interaction with a vascular bed.KNOWLEDGE CENTER
Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate ® supports your research needs. Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures.ORGANOFLOW®
Application. OrganoFlow for your research? We strongly advise using OrganoFlow to optimally control the perfusion flow in OrganoPlates. OrganoFlow allows for detailed programming of an intermitting rocking action. For evaluation purposes, a standard continuous rocker platform (see-saw) can be used. 3D CELL CULTURE VS. TRADITIONAL 2D CELL CULTURE EXPLAINED Adhesive, topographical mechanical and soluble cues in 2D and 3D 4 A lot changes when a cell moves from 2D to 3D culture, but the most obvious is the mechanical environment. HUMAN TISSUE MODELS FOR BETTER THERAPIES MIMETAS offers OrganoPlates and develops human tissue and disease models for tomorrow’s medicines, chemicals and food. Kickstart now your experiments with the most sophisticated 3D tissue culture platform or work with us to develop amazing 3D tissue and dPRODUCTS - MIMETAS
Use OrganoPlate to develop in vitro 3D tissue and disease models. Get inspired by applications, OrganoPlate, and related products to kickstart your experiments.ORGANOTEER®
OrganoTEER: how it works. Perform OrganoTEER ® measurements By characterizing tubular models with OrganoTEER ® measurements, you can perform exposure studies to evaluate cytotoxicity and inflammatory reaction to compounds over minutes, hours, and days. You will be able to do timelapse series in the incubator and under flow conditions.ORGANOPLATE® GRAFT
OrganoPlate ® Graft: how it works. Functional blood vessels are a vital connecting structure inside the body. This aspect is missing in all currently available in vitro cell culture techniques, until now. OrganoPlate ® Graft is developed for grafting tissues to a vascular bed. Its open-top design makes it possible to receive target tissues for studying interaction with a vascular bed.KNOWLEDGE CENTER
Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate ® supports your research needs. Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures.ORGANOFLOW®
Application. OrganoFlow for your research? We strongly advise using OrganoFlow to optimally control the perfusion flow in OrganoPlates. OrganoFlow allows for detailed programming of an intermitting rocking action. For evaluation purposes, a standard continuous rocker platform (see-saw) can be used. 3D CELL CULTURE VS. TRADITIONAL 2D CELL CULTURE EXPLAINED Adhesive, topographical mechanical and soluble cues in 2D and 3D 4 A lot changes when a cell moves from 2D to 3D culture, but the most obvious is the mechanical environment.OUR TECHNOLOGY
PhaseGuide™ technology. Membrane-free tissue culture OrganoPlate ® employs a unique patented liquid handling technology, called Phaseguides™. Phaseguides™ are meticulously designed meniscus pinning barriers. They enable precise, barrier-free definition of culture matrices and cells in 3D, supporting cell-cell interactions and unprecedented imaging and quantification.ABOUT US - MIMETAS
Supporting up to 64 tissue models on a single plate. Specially designed for automated workflows. Its unique PhaseGuide™ technology enables cells to interact andNEWS - MIMETAS
Leiden, April 22, 2021 - MIMETAS, the global leader in organ-on-a-chip-based disease modeling, is happy to announce the appointment of Patrice Denèfle as their Scientific Advisor.Patrice brings in longstanding scientific expertise and an extensive network in the pharmaceutical industry. His involvement will support the therapeutic research strategy and spark new collaborations withleading
APPLICATIONS
Start today with OrganoPlate®: the solution for all in vitro 3D tissue culture applications. The platform enables unique novel tissue cultures and applications. Learn moreVASCULARIZATION
OrganoPlate ® Graft: the missing link in tissue culture. OrganoPlate Graft is a variation of the OrganoPlate 2-lane and 3-lane series and incorporates MIMETAS' unique technology to grow functional microvessels to create a microvascular bed. Tissue placed onto this bed is connected to the system of human blood vessels, achieving in vitro vascularization. 2D VERSUS 3D CELL CULTURES: ADVANTAGES AND DISADVANTAGES 2D cell cultures have been used since the early 1900s. In recent years, 3D cell culture techniques have received much attention from scientists, as these might provide more accurate models of MIMETAS WINS DESHIMA AWARD FOR DUTCH-JAPANESE BUSINESS Minister for Foreign Affairs of the Netherlands Ms. Sigrid Kaag announced and congratulated MIMETAS as the winner of the prestigious award. On behalf of the Jury of the Deshima Business Awards Edith Bosch, former Dutch Judoka, added: ‘'MIMETAS is a start-up biotech company founded in 2013 which has become a global leader in organ-on-a-chip based disease and drug research.JACQUELIEN TEN DAM
This interview is part of a series of conversations with the people working at Mimetas. The 'I' in Mimetas focuses on the personal side of the scientists that drive our world. Today we have a chat with Jacquelien ten Dam, who is as CFO responsible for the Corporate Development and Finance activities at Mimetas. 7 WAYS CACO-2 CELLS CAN MAKE OR BREAK YOUR INTESTINAL Increased intestinal permeability has been described in a number of diseases, including inflammatory bowel disorders (IBD) 1, celiac disease 2, and in conditions not primarily associated with the intestines. 3 Even though the etiology of these diseases is far from clear, it is now widely accepted that the gut barrier plays an important role in health and disease. 4 Studying intestinal IMMUNOSTAINING IN THE ORGANOPLATE® 3 Version 3.2 www.mimetas.com | info@mimetas.com | +31 85 888 3161 Immunostaining in the OrganoPlate® 9. Wash chips 1x 5 min with washing solution using the volume scheme shown in step 7*
Technology
*
Products __
*
OrganoPlate® 2-lane 96 __*
Supporting up to 96 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the two channels of each chip.*
OrganoPlate® 3-lane 40 __*
Supporting up to 40 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.*
OrganoPlate® 3-lane 64 __*
Supporting up to 64 tissue models on a single plate. Specially designed for automated workflows. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.*
OrganoPlate® Graft __*
The first_ in vitro _tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues.*
OrganoReady® Caco-2 __*
Offering 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies.*
OrganoFlow® __
*
Driving precisely-controlled perfusion flow in the OrganoPlate®platform
*
OrganoTEER® __
*
Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 tissue culture chips with a few clicks, in less than one minute.*
Workshops & Trainings __*
Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modelingneeds best.
*
All Products __
*
OrganoPlate® is the solution for all _in vitro_ tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.*
Request a quote __
*
Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.*
Services __
*
Compound profiling & Screening __*
Get robust compound data in human tissue models through our OrganoServices. With proven phenotypic assays in the OrganoPlate® platform, we support your drug discovery and development needs.*
Custom Model & Assay Development __*
We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.*
Drug Development Partnerships __*
Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.*
All Services __
*
We offer several services to support your drug discovery and development needs. Find the overview here.*
Applications __
*
Perfused Tubules __
*
Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.*
Cell-Cell Interactions __*
Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.*
3D Cell Migration __*
Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.*
Angiogenesis __
*
Membrane-free microvascular formation and growth through an extracellular matrix (ECM).*
Vascularization __
*
The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.*
All Applications __
*
OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.*
Resources & Support __*
Knowledge Center __
*
Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs. Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, byour scientists.
*
Publications __
*
Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.*
Case Studies __
*
Get inspired by research done by our scientists, partners, and customers around the globe.*
Blogs __
*
Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its futureoutlook.
*
Workshops & Trainings __*
Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modelingneeds best.
*
Technical Support __*
Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.*
Request a quote __
*
Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.*
FAQ __
*
Frequently asked questions answered by our experts. Find here the answer you're looking for.*
About Mimetas __
*
Company __
*
Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.*
Contact
*
Locations
*
News
*
Events
*
Careers
*
OrganoPlate® 2-lane 96 __*
OrganoPlate® 3-lane 40 __*
OrganoPlate® 3-lane 64 __*
OrganoPlate® Graft __*
OrganoReady® Caco-2 __*
OrganoFlow® __
*
OrganoTEER® __
*
Workshops & Trainings __*
All Products __
*
Request a quote __
*
Compound profiling & Screening __*
Custom Model & Assay Development __*
Drug Development Partnerships __*
All Services __
*
Perfused Tubules __
*
Cell-Cell Interactions __*
3D Cell Migration __*
Angiogenesis __
*
Vascularization __
*
All Applications __
*
Knowledge Center __
*
Publications __
*
Case Studies __
*
Blogs __
*
Workshops & Trainings __*
Technical Support __*
Request a quote __
*
FAQ __
*
Company __
*
Contact
*
Locations
*
News
*
Events
*
Careers
*
Supporting up to 96 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the two channels of each chip.*
Supporting up to 40 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.*
Supporting up to 64 tissue models on a single plate. Specially designed for automated workflows. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.*
The first_ in vitro _tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues.*
Offering 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies.*
Driving precisely-controlled perfusion flow in the OrganoPlate®platform
*
Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 tissue culture chips with a few clicks, in less than one minute.*
Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modelingneeds best.
*
OrganoPlate® is the solution for all _in vitro_ tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.*
Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.*
Get robust compound data in human tissue models through our OrganoServices. With proven phenotypic assays in the OrganoPlate® platform, we support your drug discovery and development needs.*
We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.*
Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.*
We offer several services to support your drug discovery and development needs. Find the overview here.*
Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.*
Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.*
Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.*
Membrane-free microvascular formation and growth through an extracellular matrix (ECM).*
The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.*
OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.*
Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs. Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, byour scientists.
*
Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.*
Get inspired by research done by our scientists, partners, and customers around the globe.*
Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its futureoutlook.
*
Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modelingneeds best.
*
Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.*
Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.*
Frequently asked questions answered by our experts. Find here the answer you're looking for.*
Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.ENGLISH
日本語
中文
HUMAN TISSUE MODELS FOR BETTER THERAPIES WE CREATE GROUNDBREAKING HUMAN TISSUE AND DISEASE MODELS TO REVOLUTIONIZE TODAY’S DRUG DISCOVERY AND DEVELOPMENTOrganoPlate
Disease modeling
Phenotypic screening Versatile and scalable Organ-on-a-chip platformVascularization
_IN VITRO_ GRAFTING
PERFUSED VASCULATURETUMORS
ORGANOIDS
Angiogenesis
3D SPROUT FORMATION
Anastomosis
Tip-stalk cell hierarchy PERFUSED MICROVASCULATURE Cell-cell interactionsCO-CULTURE
COMPOUND TISSUES
EPITHELIAL-MESENCHYMAL INTERACTIONSPerfused tubules
PERMEABILITY
TRANSMIGRATION
TRANSPORT
TRANSCYTOSIS
3D cell migration
INVASION
ANGIOGENESIS
IMMUNE MIGRATION
METASTASIS
Vascularization
_IN VITRO_ GRAFTING
PERFUSED VASCULATURETUMORS
ORGANOIDS
Angiogenesis
3D SPROUT FORMATION
Anastomosis
Tip-stalk cell hierarchy PERFUSED MICROVASCULATURE Cell-cell interactionsCO-CULTURE
COMPOUND TISSUES
EPITHELIAL-MESENCHYMAL INTERACTIONSPerfused tubules
PERMEABILITY
TRANSMIGRATION
TRANSPORT
TRANSCYTOSIS
3D cell migration
INVASION
ANGIOGENESIS
IMMUNE MIGRATION
METASTASIS
Vascularization
_IN VITRO_ GRAFTING
PERFUSED VASCULATURETUMORS
ORGANOIDS
‹›
HUMAN TISSUE AND DISEASE MODEL EXPERTSExecute
COMPOUND PROFILING & SCREENING Get robust compound data in human tissue models through our OrganoServices. With proven phenotypic assays in the OrganoPlate® platform, we support your drug discovery and development needs.OrganoServices
Innovate
CUSTOM MODEL & ASSAY DEVELOPMENT We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.Custom services
Discover
DRUG DEVELOPMENT PARTNERSHIPS Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.Collaborations
LIVING INNOVATION
The 'I' in Mimetas
Henriëtte Lanz
Director of Model Development'
It should be
mandatory to
socialize with colleagues.Read more
The 'I' in Mimetas
Bas Trietsch
Chief Technology Officer'
We try to help
each other
as a team.
Read more
The 'I' in Mimetas
Jacquelien Ten Dam
Chief Financial Officer'
It always seems impossible until it’s done.Read more
The 'I' in Mimetas
Paul Vulto
CEO
'
Leveraging who you are, is the key to making a difference!Read more
The 'I' in Mimetas
Chiwan Chiang
Field Application Specialist'
A day without
laughter is a day wasted.Read more
The 'I' in Mimetas
Jos Joore
CEO
'
We want to
empower research on complex tissue biology.Read more
The 'I' in Mimetas
Nienke Wevers
Senior Scientist
'
Nothing ventured, nothing gained.Read more
The 'I' in Mimetas
Henriëtte Lanz
Director of Model Development'
It should be
mandatory to
socialize with colleagues.Read more
The 'I' in Mimetas
Bas Trietsch
Chief Technology Officer'
We try to help
each other
as a team.
Read more
The 'I' in Mimetas
Jacquelien Ten Dam
Chief Financial Officer'
It always seems impossible until it’s done.Read more
The 'I' in Mimetas
Paul Vulto
CEO
'
Leveraging who you are, is the key to making a difference!Read more
The 'I' in Mimetas
Chiwan Chiang
Field Application Specialist'
A day without
laughter is a day wasted.Read more
The 'I' in Mimetas
Jos Joore
CEO
'
We want to
empower research on complex tissue biology.Read more
The 'I' in Mimetas
Nienke Wevers
Senior Scientist
'
Nothing ventured, nothing gained.Read more
The 'I' in Mimetas
Henriëtte Lanz
Director of Model Development'
It should be
mandatory to
socialize with colleagues.Read more
‹›
Discover
'
Organoplates opened avenues that were before considered unreachableLAURA PERIN, PhD
Children's Hospital Los AngelesDiscover
'
Mimetas' tumor infiltration platform demonstrated a therapeutic effect of our compound on immune cell recruitment: we’re very excited by these proof of concept dataSCIENTIST
From a top pharma
Press Release
'
As we still do not fully understand the biological mechanisms of most diseases, we need to start embracing this complexity by using appropriate translational models.PATRICE DENÈFLE
MIMETAS' new Scientific AdvisorInnovate
'
Often you have to compromise: it's either the throughput or it's the complexity of the model. Getting both in the same platform... no other platform can do that!SCIENTIST
From a top pharma
Discover
'
Organoplates opened avenues that were before considered unreachableLAURA PERIN, PhD
Children's Hospital Los AngelesDiscover
'
Mimetas' tumor infiltration platform demonstrated a therapeutic effect of our compound on immune cell recruitment: we’re very excited by these proof of concept dataSCIENTIST
From a top pharma
Press Release
'
As we still do not fully understand the biological mechanisms of most diseases, we need to start embracing this complexity by using appropriate translational models.PATRICE DENÈFLE
MIMETAS' new Scientific AdvisorInnovate
'
Often you have to compromise: it's either the throughput or it's the complexity of the model. Getting both in the same platform... no other platform can do that!SCIENTIST
From a top pharma
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