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UTILITY
* For Patients - Find a Clinical Trial CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Developing new strategies to prevent, diagnose and treat cancers andother diseases.
Clinical Services
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Excellence in genomics, proteomics and bioinformatics for precisionmedicine.
About Us
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTREFrom Nobel roots.
Our Story
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Developing new strategies to prevent, diagnose and treat cancers andother diseases.
Clinical Services
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Expert assistance with experimental design and biotechnology development. Collaborative Services CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Harnessing cutting-edge genome sequencing and analytical techniques.Technology Platform
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Enabling new ways to process, analyze and visualize genomic data.Software Resources
CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE Realizing the social and economic benefits of genome science.Research Projects
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DEVELOPING AND DEPLOYING GENOMICS TECHNOLOGIES IN SUPPORT OF CANCER AND LIFE SCIENCES RESEARCH. Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics and bioinformatics for precision medicine. By developing and deploying cutting-edge genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets and helping the world realize the social and economic benefits of genome science.TECHNOLOGY PLATFORM
The GSC is available to support your research. We guide experimental design, facilitate the processing of complex biological samples and provide numerous sequencing and bioinformatic services with the aim of making genomics accessible to the international scientific community. Explore our technology platformsand services
, and if you have questions or would like to collaborate please fill out our contact formor speak
directly with one of our platform leaders.
The GSC is ISO27001certified
for information security management.SCIENTIFIC RESEARCH
The 15 faculty members at the GSC have a diverse range of expertise in genomics, bioinformatics, proteomics, epigenomics, immunogenetics, cancer biology, computer science and software development . Together, we apply our knowledge to advance the global understanding of cancer and other diseases with an ultimate aim toward improving human health through disease prevention, the development of novel diagnostic strategies and by uncovering new therapeutic approaches, all the while helping the world to realize the social and economic benefits ofgenome research .
CLINICAL PROGRAMS
The GSC is unique in that it fosters close collaborations between scientists and clinicians, allowing for an unencumbered focus on direct translational research. Through the Personalized OncoGenomics (POG) program , the GSC deploys whole genome and transcriptome sequencing to inform therapeutic and management strategies for late-stage cancer patients in real time. The GSC is also certified by the College of AmericanPathologists (CAP)
and the Diagnostic Accreditation Program (DAP)to
perform clinical genomic panel testing.QUESTIONS?
Please feel free to speak with one of our Platform Leaders directly: DIRECTORS & PLATFORM LEADERS DR. MARCO MARRA, PHD, FRS(C), FCAHS, OBCDirector
Distinguished Scientistmmarra@bcgsc.ca
604-675-8162 Bio __ DR. STEVEN JONES, PHD, FRS(C), FCAHSDirector
Head, Bioinformatics Distinguished Scientistsjones@bcgsc.ca
604-877-6083 Bio __ DR. MARTIN HIRST, PHDHead, Epigenomics
Senior Scientist
mhirst@bcgsc.ca
604-822-6373 Bio __ ROBYN ROSCOE, B.SC., PMP Director, Management & Administrationrroscoe@bcgsc.ca
604-707-5800 Bio __NEWS
Apr 28, 2021
DR. MARCO MARRA JOINS CANADA’S MEDICAL HALL OF FAME Today, six outstanding individuals were inducted into the Canadian Medical Hall of Fame. Among them, Dr. Marco Marra, Director of Canada’s Michael Smith Genome Sciences Centre at BC Cancer. Visit the Canadian Medical Hall of Fame website to view the 2020 InductionCeremony
* Learn more about Dr. Marco Marra joins Canada’s Medical Hall ofFame
May 03, 2021
A NOVEL TRANSCRIPTOME-BASED CLINICAL ASSAY ALLOWS FOR IMPROVED RISK GROUP STRATIFICATION OF ACUTE MYELOID LEUKEMIA PATIENTS In a new study published in Nature Communications, GSC researchers used the power of next generation sequencing technologies to develop a clinical test that improves acute myeloid leukemia patientstratification.
* Learn more about A novel transcriptome-based clinical assay allows for improved risk group stratification of acute myeloid leukemiapatients
Mar 18, 2021
A NEW METHOD FOR ANALYZING SILENCED GENES Cancers are diseases of the genome. They can result from minor changes to single or a few base pairs, known as mutations, or from larger structural changes to the genome, including how it is packaged into chromosomes and manipulated by other molecules. Understanding how things have gone wrong in specific cancers can help scientists develop better prognostic tools and treatment strategies. * Learn more about A new method for analyzing silenced genesPUBLICATIONS
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma Cancer Discovery, 2021 Hai-Feng Zhang, Christopher S Hughes, Wei Li, Jian-Zhong He, Didier Surdez, Amal M El-Naggar, Hongwei Cheng, Anna Prudova, Alberto Delaidelli, Gian Luca Negri, Xiaojun Li, Maj Sofie Orum-Madsen, Michael M Lizardo, Htoo Zarni Oo, Shane Colborne, Taras Shyp, Renata Scopim-Ribeiro, Colin A Hammond, Anne-Chloe Dhez, Sofya Langman, Jonathan Km Lim, Sonia Hy Kung, Amy Li, Anne Steino, Mads Daugaard, Seth J Parker, Ramon I Klein Geltink, Rimas J Orentas, Li-Yan Xu, Gregg B Morin, Olivier Delattre, Dimiter S Dimitrov, Poul H Sorensen An approach to rapid characterization of DMD copy number variants for prenatal risk assessment American Journal of Medical Genetics, 2021 Hui-Lin Chin, Kieran O'Neill, Kristal Louie, Lindsay Brown, Kamilla Schlade-Bartusiak, Patrice Eydoux, Rosemarie Rupps, Ali Farahani, Cornelius F Boerkoel, Steven J M Jones Postoperative outcomes for Indigenous Peoples in Canada: a systematicreview
Canadian Medical Journal, 2021 Jason A McVicar, Alana Poon, Nadine R Caron, M Dylan Bould, Jason W Nickerson, Nora Ahmad, Donna May Kimmaliardjuk, Chelsey Sheffield, Caitlin Champion, Daniel I McIsaacPAGINATION
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BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. Together with our donors, we are changing cancer outcomes for British Columbians by funding innovative research and personalized treatment and care.Donate Today
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