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APEXBIO - MCAP
mCAP is the first cap analog for the molecular biology toolbox. MCAP inserts in the correct orientation to enhance translation with a 50% chance. The other 50% of molecules can’t be a substrate for efficient translation, reducing the specific activity of the transcript. mCAP can be incorporated in a transcription by including amixture of the
APEXBIO - ROSUVASTATIN Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50of 11 nM.
APEXBIO - HUMAN B CELL CULTURE AND EXPANSION KIT Human B cell culture and expansion kit is for activation and expansion of human B cells. Human monoclonal antibodies isolated for specific antibodies are widely used in immunity studies, historical studies and therapeutic development. Memory B cells derived from peripheral blood will produce high concentration of IgG in the supernatant under APEXBIO - SPCAS9 MRNA (ARCA, 5MCTP, ΨUTP) SpCas9 mRNA (ARCA, 5mCTP, ψUTP) SpCas9 mRNA expresses an optimized version of Streptococcus pyogenes protein. It can be used with a purified guideRNA sequence for genomic DNA target recognition and cleavage in the CRISPR-Cas genome editing system. Typ APEXBIO - BIOTINYLATION REAGENTS - PROTEIN LABELING ApexBio by An Apoptosis and Epigenetics Company. Contact Us. Tel: +1-832-696-8203 Fax: +1-832-641-3177 Email: APEXBIO - RO 48-8071 ApexBio by An Apoptosis and Epigenetics Company. Physical Appearance: A solid: Storage: Store at -20°C: M.Wt: 448.37: Cas No. 161582-11-2 ATAC-SEQ LIBRARY PREPARATION KIT /1 / www.apexbt.com Protocol Cat. No. K1157 ATAC-Seq Library Preparation Kit Introduction ATAC-Seq (Assay for Transposase-Accessible Chromatin with High-throughput Sequencing) is anew method
APEXBIO - CFI-400945 ORALLY AVAILABLE, SELECTIVE INHIBITOR CFI-400945 is an orally active, potent and selective inhibitor of polo-like kinase 4.Polo-like kinase 4 (PLK4), a unique member of the Polo-like family of kinases, shares little homology with other polo-like kinases. PLK4 plays an essential role in centri APEXBIO - AMG 548|P38Α INHIBITOR,POTENT AND SELECTIVE|CAS AMG 548 is a potent and selective inhibitor of p38α with IC50 values of 0.5, 3.6, 2600 and 4100 nM for p38α, p38β, p38γ and p38δ, respectively. P38 mitogen-activated protein kinase (p38) is a serine/threonine kinase and is responsive to a variety of cel APEXBIO - ACHIEVE PERFECTION, EXPLORE THE UNKNOWNANALYTICAL SERVICESCUSTOM ORGANIC SYNTHESISCUSTOM PEPTIDE SYNTHESISBIOINFORMATICS ApexBio by An Apoptosis and Epigenetics Company. Contact Us. Tel: +1-832-696-8203 Fax: +1-832-641-3177 Email:APEXBIO - MCAP
mCAP is the first cap analog for the molecular biology toolbox. MCAP inserts in the correct orientation to enhance translation with a 50% chance. The other 50% of molecules can’t be a substrate for efficient translation, reducing the specific activity of the transcript. mCAP can be incorporated in a transcription by including amixture of the
APEXBIO - ROSUVASTATIN Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50of 11 nM.
APEXBIO - HUMAN B CELL CULTURE AND EXPANSION KIT Human B cell culture and expansion kit is for activation and expansion of human B cells. Human monoclonal antibodies isolated for specific antibodies are widely used in immunity studies, historical studies and therapeutic development. Memory B cells derived from peripheral blood will produce high concentration of IgG in the supernatant under APEXBIO - SPCAS9 MRNA (ARCA, 5MCTP, ΨUTP) SpCas9 mRNA (ARCA, 5mCTP, ψUTP) SpCas9 mRNA expresses an optimized version of Streptococcus pyogenes protein. It can be used with a purified guideRNA sequence for genomic DNA target recognition and cleavage in the CRISPR-Cas genome editing system. Typ APEXBIO - BIOTINYLATION REAGENTS - PROTEIN LABELING ApexBio by An Apoptosis and Epigenetics Company. Contact Us. Tel: +1-832-696-8203 Fax: +1-832-641-3177 Email: APEXBIO - RO 48-8071 ApexBio by An Apoptosis and Epigenetics Company. Physical Appearance: A solid: Storage: Store at -20°C: M.Wt: 448.37: Cas No. 161582-11-2 ATAC-SEQ LIBRARY PREPARATION KIT /1 / www.apexbt.com Protocol Cat. No. K1157 ATAC-Seq Library Preparation Kit Introduction ATAC-Seq (Assay for Transposase-Accessible Chromatin with High-throughput Sequencing) is anew method
APEXBIO - CFI-400945 ORALLY AVAILABLE, SELECTIVE INHIBITOR CFI-400945 is an orally active, potent and selective inhibitor of polo-like kinase 4.Polo-like kinase 4 (PLK4), a unique member of the Polo-like family of kinases, shares little homology with other polo-like kinases. PLK4 plays an essential role in centri APEXBIO - AMG 548|P38Α INHIBITOR,POTENT AND SELECTIVE|CAS AMG 548 is a potent and selective inhibitor of p38α with IC50 values of 0.5, 3.6, 2600 and 4100 nM for p38α, p38β, p38γ and p38δ, respectively. P38 mitogen-activated protein kinase (p38) is a serine/threonine kinase and is responsive to a variety of cel APEXBIO - ROMIDEPSIN (FK228)|HDAC1/HDAC2 INHIBITOR,POTENT Background. Romidepsin, also known as FK228 or depsipeptide, is potent and selective inhibitor of histone deacetylases (HDACs) which are associated with the regulation of re-expression of silenced tumor suppressor genes. It was the first HDAC inhibitor to manifest anti-tumor activity and originally isolated from a rod-shapedGram-negative
APEXBIO - CFI-400945 ORALLY AVAILABLE, SELECTIVE INHIBITOR CFI-400945 is an orally active, potent and selective inhibitor of polo-like kinase 4.Polo-like kinase 4 (PLK4), a unique member of the Polo-like family of kinases, shares little homology with other polo-like kinases. PLK4 plays an essential role in centriAPEXBIO - Z-VAD-FMK
Z-VAD-FMK, an inhibitor of ICE-like proteases, inhibits apoptosis in THP.1 cells induced by diverse stimuli1 and Fas antigen-induced apoptosis in Jurkat T-cells2. It inhibits apoptosis by blocking the activation of proCPP32 into its active form, rather th APEXBIO - SURAMIN HEXASODIUM SALT Suramin hexasodium salt, as a polysulfonated naphthylurea, is a potent competitive inhibitor of DNA topoisomerase II, with an IC50 of 5 μM. DNA topoisomerase II cuts both strands of the DNA helix simultaneously to manage DNA tangles and supercoils. Once APEXBIO - PRESCISSION PROTEASE (PSP) Description. PreScission Protease is a recombinant protease that combines human rhinovirus type 14 3C protease and GST. This protease can specifically recognize the short peptide Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro at low temperature (4°C) and digest between Gln and Gly amino acid residues. Its substrate recognition and cleavage depend not only on APEXBIO - CA 074|CATHEPSIN B INHIBITOR|CAS# 134448-10-5 CA-074, a specific cathepsin B inhibitor, also abolished the neurotoxic effects caused by Abeta42-activated BV2 cell . Co-treatment of cultures with the cathepsin B inhibitors CA-074 or Z-FA-FMK suppressed the cytostatic effects of TPA and activation o APEXBIO - FIREFLY LUCIFERASE MRNA (ARCA, 5-MOUTP) Firefly Luciferase mRNA (ARCA, 5-moUTP) expresses luciferase protein which is initially extracted from firefly Photinus pyralis. The enzyme catalyzes ATP-dependent D-luciferin oxidation to yield oxyluciferin, a singlet-excited compound that emits light when returning to its ground state. Firefly Luciferase is a frequently used bioluminescent APEXBIO - AZD4547|FGFR INHIBITOR|CAS# 1035270-39-3 AZD4547 is a potent, specific, orally bioavailable fibroblast growth factors receptor (FGFR) tyrosine kinase inhibitor. It inhibits FGFR1, FGFR2, and FGFR3 with IC50 values of 12, 2 and 40 nM, respectively. AZD4547 has also been reported to block FGFR1, FGFR2, and FGFR3 autophosphorylation with IC50 values of 0.2, 2.5, and 1.8 nM,respectively .
APEXBIO - ICI 162,846 Chemical Properties. Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. APEXBIO - RGFP966|SPECIFIC HDAC3 INHIBITOR|CAS# 1357389-11-7 RGFP966 is a selective inhibitor of HDAC3 with IC50 value of 80 nM . HDAC3 (histone deacetylase 3) is an isoform of HDACs family and plays an important role in DNA transcriptional regulation. It has been shown that HDACs involves in a variety of biolo APEXBIO - ACHIEVE PERFECTION, EXPLORE THE UNKNOWNANALYTICAL SERVICESCUSTOM ORGANIC SYNTHESISCUSTOM PEPTIDE SYNTHESISBIOINFORMATICS ApexBio by An Apoptosis and Epigenetics Company. Contact Us. Tel: +1-832-696-8203 Fax: +1-832-641-3177 Email: APEXBIO - DISTRIBUTORS Assay Matrix Pty Ltd PO BOX 3114 Ivanhoe North VIC, 3079 Australia. Tel: +61 405 701 981. Fax: +61 3 8678 3150. Email: Website: www.assaymatrix.com APEXBIO - ROSUVASTATIN Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50of 11 nM.
APEXBIO - HUMAN B CELL CULTURE AND EXPANSION KIT Human B cell culture and expansion kit is for activation and expansion of human B cells. Human monoclonal antibodies isolated for specific antibodies are widely used in immunity studies, historical studies and therapeutic development. Memory B cells derived from peripheral blood will produce high concentration of IgG in the supernatant under APEXBIO - ACHIEVE PERFECTION, EXPLORE THE UNKNOWNANALYTICAL SERVICESCUSTOM ORGANIC SYNTHESISCUSTOM PEPTIDE SYNTHESISBIOINFORMATICS ApexBio by An Apoptosis and Epigenetics Company. Contact Us. Tel: +1-832-696-8203 Fax: +1-832-641-3177 Email: APEXBIO - DISTRIBUTORS Assay Matrix Pty Ltd PO BOX 3114 Ivanhoe North VIC, 3079 Australia. Tel: +61 405 701 981. Fax: +61 3 8678 3150. Email: Website: www.assaymatrix.com APEXBIO - ROSUVASTATIN Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50of 11 nM.
APEXBIO - HUMAN B CELL CULTURE AND EXPANSION KIT Human B cell culture and expansion kit is for activation and expansion of human B cells. Human monoclonal antibodies isolated for specific antibodies are widely used in immunity studies, historical studies and therapeutic development. Memory B cells derived from peripheral blood will produce high concentration of IgG in the supernatant underAPEXBIO - Z-VAD-FMK
Z-VAD-FMK, an inhibitor of ICE-like proteases, inhibits apoptosis in THP.1 cells induced by diverse stimuli1 and Fas antigen-induced apoptosis in Jurkat T-cells2. It inhibits apoptosis by blocking the activation of proCPP32 into its active form, rather th APEXBIO - SPCAS9 MRNA (ARCA, 5MCTP, ΨUTP) SpCas9 mRNA (ARCA, 5mCTP, ψUTP) SpCas9 mRNA expresses an optimized version of Streptococcus pyogenes protein. It can be used with a purified guideRNA sequence for genomic DNA target recognition and cleavage in the CRISPR-Cas genome editing system. Typ APEXBIO - BIOTIN-TYRAMIDE Biotin-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols. TSA is an enzyme-mediated detection method that uses horseradish ATAC-SEQ LIBRARY PREPARATION KIT /1 / www.apexbt.com Protocol Cat. No. K1157 ATAC-Seq Library Preparation Kit Introduction ATAC-Seq (Assay for Transposase-Accessible Chromatin with High-throughput Sequencing) is anew method
APEXBIO - FERROSTATIN-1 (FER-1)|FERROPTOSIS INHIBITOR Ferrostatin-1 is a selective inhibitor of ferroptosis. Ferroptosis is a regulated, oxidative, nanapoptotic cell death, Ferrostatin-1 has been founded as a potent inhibitor of it. Fer-1 can attenuate oxidative, iron-dependent cancer cell death through blocking cystine import and glutathione production. APEXBIO - ROMIDEPSIN (FK228)|HDAC1/HDAC2 INHIBITOR,POTENT Background. Romidepsin, also known as FK228 or depsipeptide, is potent and selective inhibitor of histone deacetylases (HDACs) which are associated with the regulation of re-expression of silenced tumor suppressor genes. It was the first HDAC inhibitor to manifest anti-tumor activity and originally isolated from a rod-shapedGram-negative
APEXBIO - MCAP
mCAP is the first cap analog for the molecular biology toolbox. MCAP inserts in the correct orientation to enhance translation with a 50% chance. The other 50% of molecules can’t be a substrate for efficient translation, reducing the specific activity of the transcript. mCAP can be incorporated in a transcription by including amixture of the
APEXBIO - HOAT|CAS# 39968-33-7|PEPTIDE COUPLING REAGENTS| A coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue. Carpino L A etc. works demonstrated that the DIC/ APEXBIO - ROMIDEPSIN (FK228)|HDAC1/HDAC2 INHIBITOR,POTENT Romidepsin, also known as FK228 or depsipeptide, is potent and selective inhibitor of histone deacetylases (HDACs) which are associated with the regulation of re-expression of silenced tumor suppressor genes. It was the first HDAC inhibitor to manifest an APEXBIO - CA 074|CATHEPSIN B INHIBITOR|CAS# 134448-10-5 CA-074, a specific cathepsin B inhibitor, also abolished the neurotoxic effects caused by Abeta42-activated BV2 cell . Co-treatment of cultures with the cathepsin B inhibitors CA-074 or Z-FA-FMK suppressed the cytostatic effects of TPA and activation o APEXBIO - FIREFLY LUCIFERASE MRNA (ARCA, 5-MOUTP) Firefly Luciferase mRNA (ARCA, 5-moUTP) expresses luciferase protein which is initially extracted from firefly Photinus pyralis. The enzyme catalyzes ATP-dependent D-luciferin oxidation to yield oxyluciferin, a singlet-excited compound that emits light when returning to its ground state. Firefly Luciferase is a frequently used bioluminescent APEXBIO - ATAC-SEQ LIBRARY PREPARATION KIT Our product ATAC-Seq Library Preparation Kit provides a simple, convenient and time-saving tool for you to analyze epigenetic information of your cells or tissues. The kit includes a hyperactive Tn5 transposase, which fragments the DNA in open regions of chromatin APEXBIO - DISCOVERYPROBE™ FDA-APPROVED DRUG LIBRARY DiscoveryProbe™ FDA-approved drug library includes 1971 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by APEXBIO - T7 TAG PEPTIDE|PEPTIDE SEQUENCE-MASMTGGQQMG The T7 tag is an epitope tag composed of an 11-residue peptide encoded from the leader sequence of the T7 bacteriophage gene10. This gene encodes a T7 major capsid protein whose function is not clear. Epitope tags are useful for the labeling and detectionAPEXBIO - S63845
S63845 is a small molecule MCL1 inhibitor with Ki < 1.2 nM . Myeloid cell leukemia 1 (MCL1) is a pro-survival protein and belongs to BCL-2 family proteins. BCL-2 family proteins are key regulators of the mitochondrial apoptotic pathway. MCL1 is ove PROTOCOL - APEXBT.COM Protocol Tel: +1-832-696-8203; Fax: +1-832-641-3177 http://www.apexbt.com/; Email: sales@apexbt.com. 5. General principles for statistical analysis JAVASCRIPT SEEMS TO BE DISABLED IN YOUR BROWSER. For the best experience on our site, be sure to turn on Javascript in your browser.Toggle Nav
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