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PROF PAUL TIMPSON
Paul completed his PhD with Prof Margaret Frame at the Beatson Institute for Cancer Research, UK in 2002 where he assessed the interplay between Src family kinases and the actin cytoskeleton during cancer cell invasion, focusing on the role of Rho family GTPases.A/PROF CECILE KING
Cecile King’s research focus over the past 15 years has been in the field of autoimmune disease and T cell immunobiology. Cecile completed her PhD in Immunology at the Telethon Institute for Child Health/University of Western Australia (1999). At completion of the PhD, she was appointed as a Research Associate in the Department of Immunology, Scripps Research Institute in the Laboratory ofCLARIOSTAR - GARVAN
The CLARIOstar is a multifunctional microplate reader capable of performing a wide array of applications for fluorescence intensity, fluorescence polarization, timeresolved fluorescence, -FRET (e.g. ®), TRHTRF - luminescence, AlphaScreen®, and full spectrum Using BMG LABTECH’s proprietary absorbance. technology, the CLARIOstar delivers superior results in all plate formats and in all GARVAN INSTITUTE OF MEDICAL RESEARCHRESEARCHSUPPORT USNEWSEXPLORE & LEARNCAREERS & STUDIESABOUT US The Garvan Institute of Medical Research has made significant breakthroughs in the understanding and treatment of disease. We are leaders in genomic and personalised medicine, use cutting-edge technology to study, prevent and treat major diseases like cancer, osteoporosis, diabetes, obesity, immonological, skeletal and neurological disease. BONE FRACTURE RISK CALCULATOR About the bone fracture risk calculator. You can read more about the risk assessment model and scores used in the tool.. The calculator was developed using data collected in the Dubbo Osteoporosis Epidemiology Study, conducted by our Bone Biology Theme .The study, begun in 1989, includes data from more than 2,500 men and women aged 60+. FRACTURE RISK CALCULATOR The results produced by our calculator should serve as a guide only. If concerned about your fracture risk, it is also important to consult your doctor or a bone specialist. GIVE NOW - DONATE TO THE GARVAN INSTITUTE OF MEDICAL RESEARCH Donate to the Garvan Institute. You're supporting important medical research. Fully tax dedictible. One-off or regular donations. PANCREATIC CANCER CLINICAL TRIAL PROGRAM TO TARGET GENOME Garvan and UNSW Sydney researchers will establish and lead an innovative pancreatic cancer clinical trial program, thanks to a $3.75 million grant from the Cancer Institute NSW. A/PROF JOSEPH POWELL I am the Head of the Garvan-Weizmann Centre for Cellular Genomics, a Lab Head at Garvan Institute of Medical Research, and a Principal Research Fellow in the Faculty of Medicine, University of New South Wales. I obtained my PhD from the University of Edinburgh, in 2010. Throughout my PhD I was a mem PROF JACQUELINE CENTER Prof Jacqueline Center qualified as an endocrinologist in 1993, obtained a Master of Epidemiology in 1995 and a PhD in 1999. She has been working on clinical and epidemiological studies related to osteoporotic fracture and its outcomes for over 18 years.PROF PAUL TIMPSON
Paul completed his PhD with Prof Margaret Frame at the Beatson Institute for Cancer Research, UK in 2002 where he assessed the interplay between Src family kinases and the actin cytoskeleton during cancer cell invasion, focusing on the role of Rho family GTPases.A/PROF CECILE KING
Cecile King’s research focus over the past 15 years has been in the field of autoimmune disease and T cell immunobiology. Cecile completed her PhD in Immunology at the Telethon Institute for Child Health/University of Western Australia (1999). At completion of the PhD, she was appointed as a Research Associate in the Department of Immunology, Scripps Research Institute in the Laboratory ofCLARIOSTAR - GARVAN
The CLARIOstar is a multifunctional microplate reader capable of performing a wide array of applications for fluorescence intensity, fluorescence polarization, timeresolved fluorescence, -FRET (e.g. ®), TRHTRF - luminescence, AlphaScreen®, and full spectrum Using BMG LABTECH’s proprietary absorbance. technology, the CLARIOstar delivers superior results in all plate formats and in all ABOUT THE GARVAN INSTITUTE Explore & learn. Discover our science and take a tour of the Institute: hear about our breakthroughs, journey inside the body, and understand the latest in medical research. GARVAN INSTITUTE OF MEDICAL RESEARCH Explore & learn. Discover our science and take a tour of the Institute: hear about our breakthroughs, journey inside the body, and understand the latest in medical research. LUNG CANCER’S RESISTANCE TO CHEMOTHERAPY REVEALS NEW Explore & learn. Discover our science and take a tour of the Institute: hear about our breakthroughs, journey inside the body, and understand the latest in medical research. ORGANISATION STRUCTURE Explore & learn. Discover our science and take a tour of the Institute: hear about our breakthroughs, journey inside the body, and understand the latest in medical research. GIVE NOW - DONATE TO THE GARVAN INSTITUTE OF MEDICAL RESEARCH Donate to the Garvan Institute. You're supporting important medical research. Fully tax dedictible. One-off or regular donations. DONATE TO OUR RESEARCH Donate to Garvan: online, a gift in your will or bequest, donate in memory or give through your pay - your support helps fund the cures ofthe future.
TYPES OF VARIANTS
Classification based on cell type: Germline variants are variants in egg or sperm cells, and are able to be passed from parent to offspring.. Somatic variants are present only in specific cells and are generally not hereditary. Somatic variants are acquired at some point during a person’s lifetime, often due to environmental factors or errors in cell division. MOLECULAR GENETICS OF INHERITED KIDNEY DISORDERS LAB Selected Publications. Mallawaarachchi AC, Hort Y, Cowley MJ, McCabe MJ, Minoche A, Dinger ME, Shine J, Furlong TJ. Whole-genome sequencing overcomes pseudogene homology to diagnose autosomal dominant polycystic kidney disease.A/PROF CECILE KING
Cecile King’s research focus over the past 15 years has been in the field of autoimmune disease and T cell immunobiology. Cecile completed her PhD in Immunology at the Telethon Institute for Child Health/University of Western Australia (1999). At completion of the PhD, she was appointed as a Research Associate in the Department of Immunology, Scripps Research Institute in the Laboratory of DEPTH STUDY GENETIC TECHNOLOGIES, DNA & DISEASE Contact us: kccgeducation@garvan.org.au www.garvan.org.au/kccg-teachers 1 DEPTH STUDY Genetic Technologies, DNA & Disease SECONDARY SOURCED INVESTIGATION FOR HSC BIOLOGY Search the Garvan websiteDONATE
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GENOME SEQUENCING SUCCESS FOR SEVERE AUTOIMMUNE CONDITION A four-year-old girl with a painful and rare immune disorder received life-changing targeted therapy, following whole genome sequencing atGarvan.
Read more about Karla GARVAN'S ANNUAL BREAST CANCER SYMPOSIUM Hear about our significant advances in new treatments, drug resistance and metastasis, as well as new clinical trials. This FREE symposium includes Garvan researchers, oncologists and guest speakers. * 2-4 pm, Friday, 13 March 2020 * Registration is essential.Book now
PREVENTING SEVERE COVID-19 DISEASE Garvan researchers are at the forefront of the global effort to find quick solutions to COVID-19: keeping infected individuals OUT of critical care. Read about our latest research and multiple projects tackling the coronavirus. Read about our coronavirus research and support our work LEAVE A GIFT IN YOUR WILL Leaving a bequest will serve to honour your memory and be a legacy of lasting hope for future generations.Find out more
DISEASE: AT SOME POINT WE ALL HAVE TO FACE IT At Garvan, we see a future where disease can be stopped before it starts. It’s within reach.Watch the video
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PURCHASE A GIFT THAT GIVES BACK Purchase your Paspaley Kimberley Bracelet today. Paspaley donates 25 percent from each bracelet sold to Garvan’s cancer research, helping scientists change the lives of people living with rare and less commoncancer.
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AUSTRALIAN POLYGENIC RISK SYMPOSIUM The inaugural Australian Polygenic Risk Symposium will run from 18-19 November 2019 at the Garvan Institute of Medical Research in Sydney.Find out more
LATEST NEWS
Federal support for Garvan COVID-19 research03 June 2020
NHMRC Investigator Grants for Garvan researchers22 May 2020
Gene sequencing guides girl’s life-changing arthritis treatment21 May 2020
Professor John Shine AC elected as Fellow of the Royal Society 30 April 2020 More newsLATEST NEWS
Federal support for Garvan COVID-19 research03 June 2020
NHMRC Investigator Grants for Garvan researchers22 May 2020
Gene sequencing guides girl’s life-changing arthritis treatment21 May 2020
Professor John Shine AC elected as Fellow of the Royal Society 30 April 2020 More news SUBSCRIBE TO OUR MAILING LIST for updates on our latest research andfree public events:
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We acknowledge the Gadigal people of the Eora Nation, the traditional owners and custodians of the land on which the Garvan Institute of Medical Research is located. We pay respects to Elders, past, present and future, and recognise the continuing connection and contributionto this land.
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