CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo.

THE TOP 200 OF 2021

The 200 most common medications on the outpatient market -- the top

200 of 2021

DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

AMINOGLYCOSIDE CALCULATOR NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo.

THE TOP 200 OF 2021

The 200 most common medications on the outpatient market -- the top

200 of 2021

DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

AMINOGLYCOSIDE CALCULATOR NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. AMINOGLYCOSIDE CALCULATOR The following criteria are used by this calculator to determine an aminoglycoside dosing weight: In underweight patients (less than ideal body weight), actual weight is used. In normal-weight patients (100-120% ideal weight), ideal body weight is used: 2. I d e a l B W ( m e n) = 50 + 2.3 ∗ ( h e i g h t o v e r 60 i n c h e s) I d e a l

B W

THE TOP 200 OF 2021

The 200 most common medications on the outpatient market -- the top

200 of 2021

SAMPLE SIZE CALCULATOR About This Calculator. This calculator uses a number of different equations to determine the minimum number of subjects that need to be enrolled in a study in order to have sufficient statistical power to detect a treatment effect. 1. Before a study is conducted, investigators need to determine how many subjects should be included. GLUCOSE INFUSION RATE CALCULATOR Glucose infusion rate is a measure of how quickly the patient receives carbohydrates. Typically, this number should be less than 4 mg/kg/min in order to prevent hyperglycemia and steatosis. 1. This calculator uses the following equation to determine a glucose infusion rate: GIR =. (Concentration, g/100 mL) x (Infusion rate, mL/hr) x (1000 mg/g TOTAL PARENTERAL NUTRITION (TPN) MACRONUTRIENT CALCULATOR About This Calculator. This total parenteral nutrition calculator provides an empiric dose for the macronutrients included in a TPN formulation. In addition to providing an initial recommended dose, you may alter the contents of each macronutrient while maintaining a specified daily caloric requirement. This calculator is not

appropriate for

POST-HOC POWER CALCULATOR This calculator uses a variety of equations to calculate the statistical power of a study after the study has been conducted. 1. "Power" is the ability of a trial to detect a difference between two different groups. If a trial has inadequate power, it may not be able to detect a difference even though a difference truly exists. CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who ESTIMATED BODY WEIGHT LOSS (EBWL) CALCULATOR Estimated body weight loss (EBWL) describes the amount of body mass lost due to an amputation. EBWL is most commonly utilized for determining an amputee's ideal body weight, which is a function of patient height. An EBWL -adjusted ideal body weight is most commonly used for determining renal function with creatinine clearance. HAS-BLED CALCULATOR FOR ASSESSING BLEEDING RISK IN ATRIAL About This Calculator. HAS-BLED is a scoring system to estimate bleeding risk in patients with atrial fibrillation. Prior to the publication of the HAS-BLED manuscript in 2010, 1 an older, more complicated algorithm called HEMORR 2 HAGES was used. 2 HAS-BLED has gained popularity over HEMORR 2 HAGES due to its simplicity and slightly superior predictive ability. CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo. AMINOGLYCOSIDE CALCULATOR NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

ESTIMATED BODY WEIGHT LOSS (EBWL) CALCULATOR Estimated body weight loss (EBWL) describes the amount of body mass lost due to an amputation. EBWL is most commonly utilized for determining an amputee's ideal body weight, which is a function of patient height. An EBWL -adjusted ideal body weight is most commonly used for determining renal function with creatinine clearance. CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo. AMINOGLYCOSIDE CALCULATOR NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

ESTIMATED BODY WEIGHT LOSS (EBWL) CALCULATOR Estimated body weight loss (EBWL) describes the amount of body mass lost due to an amputation. EBWL is most commonly utilized for determining an amputee's ideal body weight, which is a function of patient height. An EBWL -adjusted ideal body weight is most commonly used for determining renal function with creatinine clearance. CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who AMINOGLYCOSIDE CALCULATOR The following criteria are used by this calculator to determine an aminoglycoside dosing weight: In underweight patients (less than ideal body weight), actual weight is used. In normal-weight patients (100-120% ideal weight), ideal body weight is used: 2. I d e a l B W ( m e n) = 50 + 2.3 ∗ ( h e i g h t o v e r 60 i n c h e s) I d e a l

B W

SAMPLE SIZE CALCULATOR About This Calculator. This calculator uses a number of different equations to determine the minimum number of subjects that need to be enrolled in a study in order to have sufficient statistical power to detect a treatment effect. 1. Before a study is conducted, investigators need to determine how many subjects should be included.

THE TOP 200 OF 2021

The 200 most common medications on the outpatient market -- the top

200 of 2021

TOTAL PARENTERAL NUTRITION (TPN) MACRONUTRIENT CALCULATOR About This Calculator. This total parenteral nutrition calculator provides an empiric dose for the macronutrients included in a TPN formulation. In addition to providing an initial recommended dose, you may alter the contents of each macronutrient while maintaining a specified daily caloric requirement. This calculator is not

appropriate for

GLUCOSE INFUSION RATE CALCULATOR Glucose infusion rate is a measure of how quickly the patient receives carbohydrates. Typically, this number should be less than 4 mg/kg/min in order to prevent hyperglycemia and steatosis. 1. This calculator uses the following equation to determine a glucose infusion rate: GIR =. (Concentration, g/100 mL) x (Infusion rate, mL/hr) x (1000 mg/g ESTIMATED BODY WEIGHT LOSS (EBWL) CALCULATOR Estimated body weight loss (EBWL) describes the amount of body mass lost due to an amputation. EBWL is most commonly utilized for determining an amputee's ideal body weight, which is a function of patient height. An EBWL -adjusted ideal body weight is most commonly used for determining renal function with creatinine clearance. CHADS2 CALCULATOR FOR GUIDING ANTITHROMBOTIC TREATMENT IN About This Calculator. CHADS 2 was designed as a scoring system to classify the risk of stroke in patients with atrial fibrillation. Prior to the study, 2 there were conflicting data regarding independent risk factors and their importance in predicting the risk of stroke. CHADS 2 was developed from an independent registry of Medicare-aged patients with non-rheumatic atrial fibrillation who BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. ENTERAL (TUBE FEED) NUTRITION CALCULATOR Determining Caloric Requirements. The ESPEN guidelines for critical care suggest a maximum caloric intake of 20-25 kcal/kg/day during the acute and initial phase of critical illness, but 25-30 kcal/kg/day during the anabolic recovery phase. 2 Certain patients (eg, malnourished or morbidly obese) may have different caloric requirements than the standard patient. HAS-BLED CALCULATOR FOR ASSESSING BLEEDING RISK IN ATRIAL About This Calculator. HAS-BLED is a scoring system to estimate bleeding risk in patients with atrial fibrillation. Prior to the publication of the HAS-BLED manuscript in 2010, 1 an older, more complicated algorithm called HEMORR 2 HAGES was used. 2 HAS-BLED has gained popularity over HEMORR 2 HAGES due to its simplicity and slightly superior predictive ability. CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo. AMINOGLYCOSIDE CALCULATOR DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

CHA2DS2-VASC CALCULATOR FOR GUIDING ANTITHROMBOTIC Gender and the Caveat to CHA 2 DS 2-VASc. In general, a CHA 2 DS 2-VASc score of 1 should warrant strong consideration for full oral anticoagulation. 2 The one exception, however, is in patients who have a score of 1 due to gender alone. In these patients (female < 65 years old without other risk factors), antithrombotic therapy should not be given. This special situation may not be intuitive CREATININE CLEARANCE CALCULATOR Creatinine clearance ( CrCl) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus). The additional proximal tubule secretion falsely elevates the CrCl estimate of GFR. 12. CLINICAL TOOLS AND CALCULATORS FOR MEDICAL Evidence-based clinical decision support tools and calculators for medical professionals. Includes mobile applications, advanced pharmacokinetic utilities, and a OPIOID (OPIATE) EQUIANALGESIA CONVERSION CALCULATOR Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses. 5, 7. BENZODIAZEPINE EQUIVALENTS CONVERSION CALCULATOR About This Calculator. This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosing, benzodiazepine equivalence is much less evidence-based and poorly described in the literature.In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice. VANCOMYCIN CALCULATOR Vancomycin Pharmacokinetic Models and Population Estimates. When CL vanco or Vd are unknown, population estimates are used based on published literature. In many pharmacokinetic textbooks, a single Vd (such as 0.7 L/kg) or CL vanco (such as 70% of creatinine clearance) are recommended. Literature demonstrates that these population estimates vary widely in certain patient populations, CORTICOSTEROID CONVERSION CALCULATOR Biological Half-Life. Note that biological half-life is different than plasma half-life. Plasma half-life does not accurately reflect a corticosteroid's duration of action in vivo. DIGOXIN CALCULATOR FOR HEART FAILURE AND ATRIALSEE MORE ON

CLINCALC.COM

AMINOGLYCOSIDE CALCULATOR NUMBER NEEDED TO TREAT (NNT) CALCULATOR Number Needed to Treat (NNT) represents the number of patients over a given time period that one would need to treat to achieve one additional study endpoint. As an example, in the PROSEVA trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)

with a NNT of 6.

CHA2DS2-VASC CALCULATOR FOR GUIDING ANTITHROMBOTIC Gender and the Caveat to CHA 2 DS 2-VASc. In general, a CHA 2 DS 2-VASc score of 1 should warrant strong consideration for full oral anticoagulation. 2 The one exception, however, is in patients who have a score of 1 due to gender alone. In these patients (female < 65 years old without other risk factors), antithrombotic therapy should not be given. This special situation may not be intuitive CREATININE CLEARANCE CALCULATOR Creatinine clearance ( CrCl) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus). The additional proximal tubule secretion falsely elevates the CrCl estimate of GFR. 12. AMINOGLYCOSIDE CALCULATOR The following criteria are used by this calculator to determine an aminoglycoside dosing weight: In underweight patients (less than ideal body weight), actual weight is used. In normal-weight patients (100-120% ideal weight), ideal body weight is used: 2. I d e a l B W ( m e n) = 50 + 2.3 ∗ ( h e i g h t o v e r 60 i n c h e s) I d e a l

B W

IDEAL, ADJUSTED, AND NUTRITIONAL BODY WEIGHT CALCULATOR About This Calculator. This calculator uses the Devine 1974 ideal body weight equation to describe a patient's "ideal" body weight. 1 Although this equation lacks a scientific basis, 2 it is extensively used in medicine for a variety of purposes, including drug dosing, mechanical ventilator settings, nutritional requirement assessment, and measurement of renal function. CHA2DS2-VASC CALCULATOR FOR GUIDING ANTITHROMBOTIC Gender and the Caveat to CHA 2 DS 2-VASc. In general, a CHA 2 DS 2-VASc score of 1 should warrant strong consideration for full oral anticoagulation. 2 The one exception, however, is in patients who have a score of 1 due to gender alone. In these patients (female < 65 years old without other risk factors), antithrombotic therapy should not be given. This special situation may not be intuitive PROTAMINE REVERSAL CALCULATOR About This Calculator. Protamine sulfate, a derivative of fish sperm, is commonly used for the reversal of anticoagulation effect of unfractionated heparin (UFH) and low-molecular weight heparin (LMWH). 3, 4 This calculator is intended to dose protamine in adults patients on a medicine floor and in the ICU. It is not appropriate for pediatric patients or for an operating room setting (such as

THE TOP 300 OF 2021

The 300 most common medications on the outpatient market -- the top

300 of 2021

CREATININE CLEARANCE CALCULATOR Creatinine clearance ( CrCl) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus). The additional proximal tubule secretion falsely elevates the CrCl estimate of GFR. 12. PHENYTOIN LOADING DOSE CALCULATOR Calculation Basics. The basis of loading dose calculations involves a drug's volume of distribution (Vd). For phenytoin, a Vd of 0.7 L/kg is used. The following equation is a simple pharmacokinetic equation to estimate a loading dose or resulting serum concentration of a drug. Δ C p = D o s e ∗ S V d. HAS-BLED CALCULATOR FOR ASSESSING BLEEDING RISK IN ATRIAL About This Calculator. HAS-BLED is a scoring system to estimate bleeding risk in patients with atrial fibrillation. Prior to the publication of the HAS-BLED manuscript in 2010, 1 an older, more complicated algorithm called HEMORR 2 HAGES was used. 2 HAS-BLED has gained popularity over HEMORR 2 HAGES due to its simplicity and slightly superior predictive ability. VANCOMYCIN CALCULATOR This vancomycin calculator uses a variety of published pharmacokinetic equations and principles to estimate a vancomycin dosing regimen for a patient. A regimen can be completely empiric, where the vancomycin dose is based on body weight and creatinine clearance, or a regimen may be calculated based on one or more vancomycin levels. WHAT’S THE DIFFERENCE BETWEEN ORAL AND IV MAGNESIUM The primary endpoint of the study (change in serum magnesium level after 6 to 24 hours) was greater with IV therapy than any dose of oral therapy (mean change 0.24 mg/dL vs. 0.05-0.11 mg/dL, p=0.003). Linear regression showed that the following factors were significantly associated with a greater change in magnesium level:

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CARDIOLOGY (MORE)

* CHADS2 Calculator for Atrial Fibrillation * CHADS2-VASc Calculator for Atrial Fibrillation * Digoxin Calculator for Heart Failure and Atrial Fibrillation * HAS-BLED Calculator for Atrial Fibrillation * Interactive Visualization Tool for 10-Year ASCVD Risk * Pooled Cohort 10-Year ASCVD Risk Assessment Equations * Protamine Reversal Calculator CRITICAL CARE (MORE) * Acute Physiology and Chronic Health Evaluation (APACHE II)

Calculator

* Combination ICU Mortality Calculator (APACHE II, SAPS II, SOFA) * Sequential Organ Failure Assessment (SOFA) Calculator * Simplified Acute Physiology Score (SAPS II) Calculator ENDOCRINOLOGY (MORE) * Corticosteroid Conversion Calculator INFECTIOUS DISEASE (MORE) * Aminoglycoside Calculator * Colistin Calculator * EUCAST MIC Breakpoint Tables * Printable Aminoglycoside Nomograms * Vancomycin Calculator

NEPHROLOGY (MORE)

* Creatinine Clearance and GFR Calculator * IDMS to Conventional Serum Creatinine

NEUROLOGY (MORE)

* Benzodiazepine Equivalence Calculator * Opioid Equianalgesic Calculator * Phenytoin (Dilantin) Correction Calculator * Phenytoin Correction for Concurrent Valproic Acid * Phenytoin Loading Dose Calculator

NUTRITION (MORE)

* Enteral and Parenteral Nutrition Summary * Enteral Nutrition Calculator * Glucose Infusion Rate Calculator * Total Parenteral Nutrition (TPN) Macronutrient Calculator PHARMACOKINETICS (MORE) * Drug Dosing in Obesity Reference Table * Estimated Body Weight Loss Calculator for Amputations * Ideal Body Weight Calculator

PHARMACY (MORE)

* DrugSpell Dictionary File * DrugStats Database * How to Pronounce the Top 250 Drugs * NAPLEX First-Time Pass Rates

STATISTICS (MORE)

* Fragility Index Calculator * Number Needed to Treat * Odds Ratio to Risk Ratio Conversion * Post-hoc Power Calculator * Sample Size Calculator

A

* Acute Physiology and Chronic Health Evaluation (APACHE II)

Calculator

* Aminoglycoside Calculator

B

* Benzodiazepine Equivalence Calculator

C

* CHADS2 Calculator for Atrial Fibrillation * CHADS2-VASc Calculator for Atrial Fibrillation * Colistin Calculator * Combination ICU Mortality Calculator (APACHE II, SAPS II, SOFA) * Corticosteroid Conversion Calculator * Creatinine Clearance and GFR Calculator

D

* Digoxin Calculator for Heart Failure and Atrial Fibrillation * Drug Dosing in Obesity Reference Table * DrugSpell Dictionary File * DrugStats Database

E

* Enteral and Parenteral Nutrition Summary * Enteral Nutrition Calculator * Estimated Body Weight Loss Calculator for Amputations * EUCAST MIC Breakpoint Tables

F

* Fragility Index Calculator

G

* Glucose Infusion Rate Calculator

H

* HAS-BLED Calculator for Atrial Fibrillation * How to Pronounce the Top 250 Drugs

I

* Ideal Body Weight Calculator * IDMS to Conventional Serum Creatinine * Interactive Visualization Tool for 10-Year ASCVD Risk

N

* NAPLEX First-Time Pass Rates * Number Needed to Treat

O

* Odds Ratio to Risk Ratio Conversion * Opioid Equianalgesic Calculator

P

* Phenytoin (Dilantin) Correction Calculator * Phenytoin Correction for Concurrent Valproic Acid * Phenytoin Loading Dose Calculator * Pooled Cohort 10-Year ASCVD Risk Assessment Equations * Post-hoc Power Calculator * Printable Aminoglycoside Nomograms * Protamine Reversal Calculator

S

* Sample Size Calculator * Sequential Organ Failure Assessment (SOFA) Calculator * Simplified Acute Physiology Score (SAPS II) Calculator

T

* Total Parenteral Nutrition (TPN) Macronutrient Calculator

V

* Vancomycin Calculator

November 2018

* DrugSpell Dictionary File (_11/19/2018)_

April 2017

* Protamine Reversal Calculator (_4/4/2017)_

November 2016

* DrugStats Database (_11/27/2016)_

August 2016

* Fragility Index Calculator

(_8/18/2016)_

December 2015

* IDMS to Conventional Serum Creatinine

(_12/2/2015)_

August 2015

* Colistin Calculator (_8/23/2015)_

July 2015

* How to Pronounce the Top 250 Drugs

(_7/17/2015)_

* NAPLEX First-Time Pass Rates (_7/14/2015)_

January 2014

* Estimated Body Weight Loss Calculator for Amputations

(_1/2/2014)_

December 2013

* Interactive Visualization Tool for 10-Year ASCVD Risk

(_12/7/2013)_

November 2013

* Pooled Cohort 10-Year ASCVD Risk Assessment Equations

(_11/12/2013)_

October 2013

* Benzodiazepine Equivalence Calculator

(_10/19/2013)_

* Enteral and Parenteral Nutrition Summary

(_10/12/2013)_

* Number Needed to Treat (_10/8/2013)_ * Odds Ratio to Risk Ratio Conversion

(_10/4/2013)_

February 2013

* Enteral Nutrition Calculator

(_2/24/2013)_

* HAS-BLED Calculator for Atrial Fibrillation

(_2/24/2013)_

* CHADS2 Calculator for Atrial Fibrillation

(_2/1/2013)_

* CHADS2-VASc Calculator for Atrial Fibrillation

(_2/1/2013)_

* Phenytoin Loading Dose Calculator

(_2/1/2013)_

November 2012

* Printable Aminoglycoside Nomograms

(_11/4/2012)_

* Phenytoin Correction for Concurrent Valproic Acid

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