DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. SHORT-SIGHTEDNESS IS REACHING EPIDEMIC PROPORTIONS. … THE MARCH OF MYOPIA East Asian countries have seen a steep rise in short-sightedness over the past 50 years. The condition is caused by a

slightly

PHYSICAL EXERCISE PERFORMED FOUR HOURS AFTER LEARNING Current Biology Report Physical Exercise Performed Four Hours after Learning Improves Memory Retention and Increases Hippocampal Pattern Similarity during Retrieval CELL METABOLISM ARTICLE Cell Metabolism Article Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges Amandine Chaix,1 Amir Zarrinpar,1,2 Phuong Miu,1 and Satchidananda Panda1,* 1Salk Institute for Biological Studies, La Jolla, CA 92037, USA 2Division of Gastroenterology, University of California, San Diego, La Jolla, CA 92093, USA ANEMIA FERROPÉNICA: SUGESTÕES TERAPÊUTICAS 4 Na anemia ferropénica, a dose diária de ferro elementar para um adulto deve ser de 100 a 200 mg.12,13 É importante não confundir dose de ferro elementar com a dose do sal de ferro (exemplo gluconato, proteinosuccilinato, sulfato, etc.) presente no comprimido, na cápsula, nas ampolas ou DNA-REPAIR DEFECTS AND OLAPARIB IN METASTATIC PROSTATE CANCER Title: DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer Author: Mateo Joaquin, Carreira Suzanne, Sandhu Shahneen, Miranda Susana, Mossop Helen, Perez WIDESPREAD SEASONAL GENE EXPRESSION REVEALS ANNUAL Seasonality of circadian clock genes Relative Log2 (expression) Relative log2 (expression) Seasonality of ARNTL, VDR, B2M and GAPDH gene expression 1.04×10–23 1.62×10–06 9.18×10–01 4.11×10–01 Morning and afternoon clinics STAND UP FOR HEALTH AVOIDING SEDENTARY BEHAVIOUR MIGHT for obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, as well as total mortality in sedentary individuals, inde-pendent of the number of total exercise sessions per week or DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. SHORT-SIGHTEDNESS IS REACHING EPIDEMIC PROPORTIONS. … THE MARCH OF MYOPIA East Asian countries have seen a steep rise in short-sightedness over the past 50 years. The condition is caused by a

slightly

PHYSICAL EXERCISE PERFORMED FOUR HOURS AFTER LEARNING Current Biology Report Physical Exercise Performed Four Hours after Learning Improves Memory Retention and Increases Hippocampal Pattern Similarity during Retrieval CELL METABOLISM ARTICLE Cell Metabolism Article Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges Amandine Chaix,1 Amir Zarrinpar,1,2 Phuong Miu,1 and Satchidananda Panda1,* 1Salk Institute for Biological Studies, La Jolla, CA 92037, USA 2Division of Gastroenterology, University of California, San Diego, La Jolla, CA 92093, USA ANEMIA FERROPÉNICA: SUGESTÕES TERAPÊUTICAS 4 Na anemia ferropénica, a dose diária de ferro elementar para um adulto deve ser de 100 a 200 mg.12,13 É importante não confundir dose de ferro elementar com a dose do sal de ferro (exemplo gluconato, proteinosuccilinato, sulfato, etc.) presente no comprimido, na cápsula, nas ampolas ou DNA-REPAIR DEFECTS AND OLAPARIB IN METASTATIC PROSTATE CANCER Title: DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer Author: Mateo Joaquin, Carreira Suzanne, Sandhu Shahneen, Miranda Susana, Mossop Helen, Perez WIDESPREAD SEASONAL GENE EXPRESSION REVEALS ANNUAL Seasonality of circadian clock genes Relative Log2 (expression) Relative log2 (expression) Seasonality of ARNTL, VDR, B2M and GAPDH gene expression 1.04×10–23 1.62×10–06 9.18×10–01 4.11×10–01 Morning and afternoon clinics STAND UP FOR HEALTH AVOIDING SEDENTARY BEHAVIOUR MIGHT for obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, as well as total mortality in sedentary individuals, inde-pendent of the number of total exercise sessions per week or DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

DURATION AND TIMING OF SLEEP ARE ASSOCIATED WITH BRIEF REPORT Duration and Timing of Sleep are Associated with Repetitive Negative Thinking Jacob A. Nota • Meredith E. Coles Springer Science+Business Media New York 2014 OXYTOCIN-GAZE POSITIVE LOOP AND THE COEVOLUTION OF HUMAN The dilution hypothesis provides an alternative framework with which to explain observations of the apparent recalcitrance of DOC and lends a physiological meaning to the operationally de- A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate USE OF COMBINED ORAL CONTRACEPTIVES AND RISK OF VENOUS RESEARCH the bmj | BMJ 2015;350: h2135 | doi: 10.1136/bmj.h2135 3 the analysis. No use in the last year was a reference cat - egory for all analyses unless otherwise stated. We included the category of past use

in the analysis

PREDICTED GLOBAL DISTRIBUTION OF BURKHOLDERIA Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis Direk Limmathurotsakul1,2,3*, Nick Golding1, David A. B. Dance4,5,JaneP.Messina6 STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. FOREVER YOUNG(ER): POTENTIAL AGE-DEFYING EFFECTS OF LONG ORIGINAL RESEARCH ARTICLE published: 21 January 2015 doi: 10.3389/fpsyg.2014.01551 Forever Young(er): potential age-defying effects of long-term meditation on gray matter atrophy ELLAGIC ACID MODULATES LIPID ACCUMULATION IN PRIMARY HUMAN Ellagic acid modulates lipid accumulation in primary human adipocytes and human hepatoma Huh7 cells via discrete mechanisms Meshail Oklaa,b,1, Inhae Kanga,b,1,DaMiKima, Vishnupriya Gourinenia, Neil Shayc, Liwei Gua, Soonkyu Chunga,b,⁎ aDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, USA bDepartment of Nutrition and Health Sciences, University of METHYLOME-WIDE ANALYSIS OF CHRONIC HIV INFECTION REVEALS Article Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Graphical Abstract

STIMULATION OF BRAIN GLUCOSE UPTAKE BY CANNABINOID CB2 T D ACCEPTED MANUSCRIPT Stimulation of brain glucose uptake by cannabinoid CB 2 receptors and its therapeutic potential in Alzheimer’s disease Running title: CB 2Rs stimulate cerebral glucose uptake Attila Köfalvi 1,2, Cristina Lemos 1$, Ana M. Martín-Moreno 3,4,#, Bárbara S. Pinheiro 1$, Luis García-García 5, Miguel A. Pozo 5,6, Ângela Valério-Fernandes1, Rui O. Beleza 1, A NEW ANTIBIOTIC KILLS PATHOGENS WITHOUT DETECTABLE RESISTANCE MurG-,FemX-,andPBP2-catalysedreactionsusingradiolabelledsub-strates,showedanalmostcompleteinhibitionatatwofoldmolarexcess ofteixobactinwithrespecttothelipidsubstrate ARTICLES YEARS OF LIFE LOST AND HEALTHY LIFE-YEARS LOST years of life. obesity. SHORT-SIGHTEDNESS IS REACHING EPIDEMIC PROPORTIONS. … THE MARCH OF MYOPIA East Asian countries have seen a steep rise in short-sightedness over the past 50 years. The condition is caused by a

slightly

PHYSICAL EXERCISE PERFORMED FOUR HOURS AFTER LEARNING Current Biology Report Physical Exercise Performed Four Hours after Learning Improves Memory Retention and Increases Hippocampal Pattern Similarity during Retrieval CELL METABOLISM ARTICLE Cell Metabolism Article Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges Amandine Chaix,1 Amir Zarrinpar,1,2 Phuong Miu,1 and Satchidananda Panda1,* 1Salk Institute for Biological Studies, La Jolla, CA 92037, USA 2Division of Gastroenterology, University of California, San Diego, La Jolla, CA 92093, USA ANEMIA FERROPÉNICA: SUGESTÕES TERAPÊUTICAS 4 Na anemia ferropénica, a dose diária de ferro elementar para um adulto deve ser de 100 a 200 mg.12,13 É importante não confundir dose de ferro elementar com a dose do sal de ferro (exemplo gluconato, proteinosuccilinato, sulfato, etc.) presente no comprimido, na cápsula, nas ampolas ou DNA-REPAIR DEFECTS AND OLAPARIB IN METASTATIC PROSTATE CANCER Title: DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer Author: Mateo Joaquin, Carreira Suzanne, Sandhu Shahneen, Miranda Susana, Mossop Helen, Perez WIDESPREAD SEASONAL GENE EXPRESSION REVEALS ANNUAL Seasonality of circadian clock genes Relative Log2 (expression) Relative log2 (expression) Seasonality of ARNTL, VDR, B2M and GAPDH gene expression 1.04×10–23 1.62×10–06 9.18×10–01 4.11×10–01 Morning and afternoon clinics STAND UP FOR HEALTH AVOIDING SEDENTARY BEHAVIOUR MIGHT for obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, as well as total mortality in sedentary individuals, inde-pendent of the number of total exercise sessions per week or Toggle navigationBANCO DA SAÚDE

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