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ADOOQ® BIOSCIENCE
AdooQ BioScience is a leading supplier of inhibitors and compound libraries. we have been a renowned name engaged in manufacturing and supplying small molecule inhibitors including kinase inhibitors on kinds of signaling pathways, such as PI3K, AKT, HDAC, MAPK , PARP,CDK,etc.
FP-BIOTIN | ≥99%(HPLC) | ADOOQ® The dilution calculator equation. The Adooq dilution calculator is based on the following equation: Concentration (start) x Volume (start) = Concentration (final) x Volume (final) This equation is commonly abbreviated as: C 1 V 1 = C 2 V 2. An example of a dilution calculation using the Adooq dilution calculator. WS6 | ≥99%(HPLC) | EBP1 INHIBITOR | ADOOQ® The dilution calculator equation. The Adooq dilution calculator is based on the following equation: Concentration (start) x Volume (start) = Concentration (final) x Volume (final) This equation is commonly abbreviated as: C 1 V 1 = C 2 V 2. An example of a dilution calculation using the Adooq dilution calculator. SHIKONIN | ≥99%(HPLC) | PTEN INHIBITOR | ADOOQ® In vitro (25°C) DMSO 50 mg/mL (173.43 mM) Water: Insoluble Ethanol: 20 mg/mL (69.37 mM) In vivo: 2% DMSO+30% PEG 300+2% Tween 80+ddH2O : 2 mg/mL * 100-fold selectivity over CDK1/cyclin B and CDK5/p25. Next day delivery by 10:00 a.m. Order now. Products are for laboratory researchuse only.
GALANTHAMINE HYDROBROMIDE In vitro (25°C) DMSO Insoluble Water: 31 mg/mL (84.17 mM) Ethanol: Insoluble : In vivo: Saline: 19 mg/mL * 100 nmol/L against a panel of300 kinases.
AWD 131-138
AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. Next day delivery by 10:00 a.m. Order now. Products are for laboratory research use only. WS6 | ≥99%(HPLC) | EBP1 INHIBITOR | ADOOQ® The dilution calculator equation. The Adooq dilution calculator is based on the following equation: Concentration (start) x Volume (start) = Concentration (final) x Volume (final) This equation is commonly abbreviated as: C 1 V 1 = C 2 V 2. An example of a dilution calculation using the Adooq dilution calculator. BCH | ≥99%(HPLC) | LAT1 INHIBITOR | ADOOQ® BCH is an inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. Products are for laboratory research use only. Not for human use. We do not sell to patients. REPARIXIN | ≥99%(HPLC) | CXCL8/CXCR1/2 INHIBITOR | ADOOQ® Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM). GRAVEOLINE | ≥99%(HPLC) | ADOOQ® The dilution calculator equation. The Adooq dilution calculator is based on the following equation: Concentration (start) x Volume (start) = Concentration (final) x Volume (final) This equation is commonly abbreviated as: C 1 V 1 = C 2 V 2. An example of a dilution calculation using the Adooq dilution calculator. IOVERSOL | ≥99%(HPLC) | ADOOQ® Storage. Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. Download Ioversol SD file. Products Specification Data Sheet. MG-262 | ≥99%(HPLC) | PROTEASOME INHIBITOR | ADOOQ® MG-262, a boronic peptide acid, is a potent proteasome inhibitor that selectively and reversibly inhibits the chymotryptic activity of the proteasome. Next day delivery by 10:00 a.m. Order now. Products are for laboratory research use only. CYPROHEPTADINE HYDROCHLORIDE Cyproheptadine hydrochloride is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. Next day delivery by 10:00 a.m. Order now. Products are for laboratory research use only. Not for human use. We do not sell to patients. LXS196 | ≥99%(HPLC) | PKC INHIBITOR | ADOOQ® LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It TAK-441 | ≥99%(HPLC) | HEDGEHOG INHIBITOR | ADOOQ® CAS NO. 1186231-83-3. TAK-441 is a pyrrolo pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor. Next day delivery by 10:00 a.m. Order now. Products are for laboratory research use only. Not for human use. CP-690550 | JAK3 INHIBITOR | BUY TOFACITINIB CITRATE FROM CP-690550 (Tofacitinib citrate) is an orally available, highly selective inhibitor of the Janus kinase (JAK) family of enzymes. Next day delivery by 10:00 a.m. Order now. Products are for laboratory research use only. Not for human use. This site uses cookies to analyze your use of our products and services, assist with navigation and marketing, and provide you with the best user experience possible. Please click 'Accept' or visit our Privacy Policy to find out how to remove / amend them. Learn MoreAccept
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You have no items in your shopping cart. * __ Signaling Pathways*
* Epigenetics
* HDAC
* PARP
* JAK
* Pim
* Aurora Kinase
* Sirtuins
* Epigenetic Reader Domain * Histone Demethylases * DNA Methyltransferases * Histone Acetyltransferases * Histone Methyltransferase * Protein Arginine Methyltransferases * Protein serine/threonine phosphatase * Protein Tyrosine Phosphatase* Apoptosis
* Bcl-2 Family
* Caspase
* p53
* TNF-α
* IAP
* MDM2
* PERK
* Survivin
* RIP Kinase
* ASK
* c-Ret
* Protein kinase D (PKD)* PI3K / Akt / mTOR
* Akt
* PI3K
* mTOR
* PDK1
* DNA-PK
* RSK
* GSK-3
* AMPK
* MELK
* ATM / ATR
* Protein Tyrosine Kinases* EGFR/HER2
* FGFR
* PDGFR
* VEGFR
* IGF-1R
* FLT3
* c-MET
* ALK
* Src
* c-Kit
* Tie-2
* Tyrosine kinase
* Trk Receptors
* CSF-1R
* TAM Receptor
* Ephrin Receptor
* ITK
* IRAK
* Angiogenesis
* EGFR / HER2
* FGFR
* PDGFR
* VEGFR
* VDA
* HIF
* FLT3
* ALK
* BTK
* FAK
* Syk
* Bcr-Abl
* JAK / Stat
* JAK
* Stat
* Pim
* EGFR/HER2
* MAPK
* MEK
* ERK
* p38-MAPK
* JNK/c-Jun
* AP-1
* Raf
* TOPK
* MNK
* MLK
* KLF
* GPCR / G Protein
* 5-HT Receptors
* Adrenergic Receptors * Histamine Receptors* Opioid Receptors
* Metabotropic glutamate receptors (mGluR) * Melatonin Receptors* Peptide Receptors
* Smoothened Receptors* CXCR
* G Protein
* Platelet-Activating Factor (PAF) Receptors * Endothelin Receptors* LPA Receptor
* Prostanoid Receptors * Adenosine Receptors * Cannabinoid Receptors * Neurotensin Receptors* Orexin Receptors
* Somatostatin Receptors * Neurokinin Receptors * Protease-Activated Receptors (PAR)* S1P Receptor
* CGRP Receptor
* Sigma receptor
* Guanylate Cyclase
* cAMP
* Glucagon Receptor
* GHSR
* Bombesin Receptors * Imidazoline Receptor* CCK
* GLP-1 receptors
* Calcium-Sensing Receptor* Cell Cycle
* Chk
* CDK
* Aurora Kinase
* PLK
* ROCK
* c-Myc
* Wee1
* Ras
* DYRK
* G-quadruplex
* DNA Damage
* HDAC
* PARP
* DNA-PK
* Topoisomerase
* Telomerase
* ATM / ATR
* DNA, RNA Synthesis * RNA/DNA Polymerase* DNA alkylator
* Synthases / Synthetases* MTH1
* Sirtuins
* IRE1
* DNA Stain
* Cytoskeleton
* Microtubules
* PAK
* Dynamin
* Integrin
* Kinesin
* Mps1
* Gap Junction Protein* Cell Metabolism
* Cytochrome P450
* PPAR
* PDE
* HSP
* Hydroxylases
* Factor Xa
* MAO
* DHFR
* Dehydrogenases
* Procollagen C-proteinase * Carbonic Anhydrase* LXR
* FAAH
* CETP
* Ferroptosis
* HMG-CoA Reductase
* FXR
* IDO
* Retinoid Receptor
* Lipase
* Phospholipases
* Lipoxygenase
* AhR
* NAMPT
* GLUT
* Antimetabolite
* Lipid Metabolism
* Neuronal Metabolism* SREBP
* LDL
* Foxo1
* DGAT
* Farnesyl Transferase* CRM1
* Thioredoxin
* Vitamin
* Decarboxylase
* ACLY
* Fatty acid synthase (FASN)* Glucokinase
* Lactate dehydrogenase A (LDHA) * Oxidative Phosphorylation* PFKFB3
* Ribonucleotide Reductase * Autophagy Signaling* Autophagy
* LRRK2
* CXCR
* Immunology & Inflammation* IL Receptor
* COX
* CCR
* Toll-like Receptors* CXCR
* ROS
* NOS
* Keap1-Nrf2
* LTR
* MALT
* PD-1/PD-L1
* NADPH oxidase
* Immunology & Inflammation related* NF-kB/IkB
* NF-κB
* IKK/IκB
* HDAC
* TGF-β / Smad
* TGF-β / Smad Inhibitors * Protein Kinase C (PKC) * Protein Kinase A (PKA)* ROCK
* Neuronal Signaling* β-Amyloid
* γ-Secretase
* Beta-secretase (BACE)* COX
* GABA Receptors
* NMDA Receptors
* CaMK
* AChR
* P2X Receptor
* Purinergic (P2Y) Receptors* GlyT
* Proteases
* Caspase
* γ-Secretase
* Proteasome
* HCV Protease
* HIV Protease
* DPP-4
* Cysteine protease
* Serine Protease
* Aminopeptidase
* Thrombin
* MMP
* Tyrosinase
* Carboxypeptidases
* Glutaminase
* Elastases
* ADAMs
* Microbiology
* Reverse Transcriptase* Integrase
* HCV Protease
* HIV Protease
* CCR
* Antifection
* Stem Cells / Wnt
* Hedgehog
* Wnt
* β-catenin
* Casein Kinase
* Smoothened
* GSK-3
* Hippo
* γ-Secretase
* Membrane Transporters/Ion Channels* ATPase
* CFTR
* Calcium Channels
* Sodium Channels
* Potassium Channels* Chloride Channels
* SGLT
* Monocarboxylate transporters (MCT)* AMPA receptor
* P-gp
* CRM1
* TRP Channel
* TRPV
* Glutamate (EAAT) Transporters * Serotonin Transporter* Proton Pump
* OCT
* NCX
* BCRP
* MRP
* Na+/H+ Exchanger
* Endocrinology / Hormones * Estrogen Receptors * Progesterone Receptors * Androgen Receptors* GPR
* 5-alpha-reductase
* Pregnane X Receptors * renin-angiotensin-aldosterone system (RAAS)* Aromatase
* Glucocorticoid receptors * Vitamin D Receptors* GnRH receptor
* ROR
* Apelin Receptors
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* Acyltransferases
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Inhibitors by Signaling Pathways* Epigenetics
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* __ Signaling Pathways*
* Epigenetics
* HDAC
* PARP
* JAK
* Pim
* Aurora Kinase
* Sirtuins
* Epigenetic Reader Domain * Histone Demethylases * DNA Methyltransferases * Histone Acetyltransferases * Histone Methyltransferase * Protein Arginine Methyltransferases * Protein serine/threonine phosphatase * Protein Tyrosine Phosphatase* Apoptosis
* Bcl-2 Family
* Caspase
* p53
* TNF-α
* IAP
* MDM2
* PERK
* Survivin
* RIP Kinase
* ASK
* c-Ret
* Protein kinase D (PKD)* PI3K / Akt / mTOR
* Akt
* PI3K
* mTOR
* PDK1
* DNA-PK
* RSK
* GSK-3
* AMPK
* MELK
* ATM / ATR
* Protein Tyrosine Kinases* EGFR/HER2
* FGFR
* PDGFR
* VEGFR
* IGF-1R
* FLT3
* c-MET
* ALK
* Src
* c-Kit
* Tie-2
* Tyrosine kinase
* Trk Receptors
* CSF-1R
* TAM Receptor
* Ephrin Receptor
* ITK
* IRAK
* Angiogenesis
* EGFR / HER2
* FGFR
* PDGFR
* VEGFR
* VDA
* HIF
* FLT3
* ALK
* BTK
* FAK
* Syk
* Bcr-Abl
* JAK / Stat
* JAK
* Stat
* Pim
* EGFR/HER2
* MAPK
* MEK
* ERK
* p38-MAPK
* JNK/c-Jun
* AP-1
* Raf
* TOPK
* MNK
* MLK
* KLF
* GPCR / G Protein
* 5-HT Receptors
* Adrenergic Receptors * Histamine Receptors* Opioid Receptors
* Metabotropic glutamate receptors (mGluR) * Melatonin Receptors* Peptide Receptors
* Smoothened Receptors* CXCR
* G Protein
* Platelet-Activating Factor (PAF) Receptors * Endothelin Receptors* LPA Receptor
* Prostanoid Receptors * Adenosine Receptors * Cannabinoid Receptors * Neurotensin Receptors* Orexin Receptors
* Somatostatin Receptors * Neurokinin Receptors * Protease-Activated Receptors (PAR)* S1P Receptor
* CGRP Receptor
* Sigma receptor
* Guanylate Cyclase
* cAMP
* Glucagon Receptor
* GHSR
* Bombesin Receptors * Imidazoline Receptor* CCK
* GLP-1 receptors
* Calcium-Sensing Receptor* Cell Cycle
* Chk
* CDK
* Aurora Kinase
* PLK
* ROCK
* c-Myc
* Wee1
* Ras
* DYRK
* G-quadruplex
* DNA Damage
* HDAC
* PARP
* DNA-PK
* Topoisomerase
* Telomerase
* ATM / ATR
* DNA, RNA Synthesis * RNA/DNA Polymerase* DNA alkylator
* Synthases / Synthetases* MTH1
* Sirtuins
* IRE1
* DNA Stain
* Cytoskeleton
* Microtubules
* PAK
* Dynamin
* Integrin
* Kinesin
* Mps1
* Gap Junction Protein* Cell Metabolism
* Cytochrome P450
* PPAR
* PDE
* HSP
* Hydroxylases
* Factor Xa
* MAO
* DHFR
* Dehydrogenases
* Procollagen C-proteinase * Carbonic Anhydrase* LXR
* FAAH
* CETP
* Ferroptosis
* HMG-CoA Reductase
* FXR
* IDO
* Retinoid Receptor
* Lipase
* Phospholipases
* Lipoxygenase
* AhR
* NAMPT
* GLUT
* Antimetabolite
* Lipid Metabolism
* Neuronal Metabolism* SREBP
* LDL
* Foxo1
* DGAT
* Farnesyl Transferase* CRM1
* Thioredoxin
* Vitamin
* Decarboxylase
* ACLY
* Fatty acid synthase (FASN)* Glucokinase
* Lactate dehydrogenase A (LDHA) * Oxidative Phosphorylation* PFKFB3
* Ribonucleotide Reductase * Autophagy Signaling* Autophagy
* LRRK2
* CXCR
* Immunology & Inflammation* IL Receptor
* COX
* CCR
* Toll-like Receptors* CXCR
* ROS
* NOS
* Keap1-Nrf2
* LTR
* MALT
* PD-1/PD-L1
* NADPH oxidase
* Immunology & Inflammation related* NF-kB/IkB
* NF-κB
* IKK/IκB
* HDAC
* TGF-β / Smad
* TGF-β / Smad Inhibitors * Protein Kinase C (PKC) * Protein Kinase A (PKA)* ROCK
* Neuronal Signaling* β-Amyloid
* γ-Secretase
* Beta-secretase (BACE)* COX
* GABA Receptors
* NMDA Receptors
* CaMK
* AChR
* P2X Receptor
* Purinergic (P2Y) Receptors* GlyT
* Proteases
* Caspase
* γ-Secretase
* Proteasome
* HCV Protease
* HIV Protease
* DPP-4
* Cysteine protease
* Serine Protease
* Aminopeptidase
* Thrombin
* MMP
* Tyrosinase
* Carboxypeptidases
* Glutaminase
* Elastases
* ADAMs
* Microbiology
* Reverse Transcriptase* Integrase
* HCV Protease
* HIV Protease
* CCR
* Antifection
* Stem Cells / Wnt
* Hedgehog
* Wnt
* β-catenin
* Casein Kinase
* Smoothened
* GSK-3
* Hippo
* γ-Secretase
* Membrane Transporters/Ion Channels* ATPase
* CFTR
* Calcium Channels
* Sodium Channels
* Potassium Channels* Chloride Channels
* SGLT
* Monocarboxylate transporters (MCT)* AMPA receptor
* P-gp
* CRM1
* TRP Channel
* TRPV
* Glutamate (EAAT) Transporters * Serotonin Transporter* Proton Pump
* OCT
* NCX
* BCRP
* MRP
* Na+/H+ Exchanger
* Endocrinology / Hormones * Estrogen Receptors * Progesterone Receptors * Androgen Receptors* GPR
* 5-alpha-reductase
* Pregnane X Receptors * renin-angiotensin-aldosterone system (RAAS)* Aromatase
* Glucocorticoid receptors * Vitamin D Receptors* GnRH receptor
* ROR
* Apelin Receptors
* Transferases
* Acyltransferases
* Phosphorylases
* Protein Prenyltransferases* SphK
* Ubiquitin
* E1 activating
* E2 conjugating
* E3 ligase
* DUB
* p97
* CRISPR
* Others
* Other inhibitors
* Reagents
* β-lactamase
* Gluconeogenesis
* Cholinesterases
* Aldose Reductase
* Nitric Oxide Signaling* Adenylyl Cyclase
* IDH1
* PTEN
* Phosphatase
* PKG
* ACAT
* NFAT
* DAPK
* Peptides
* gp120/CD4
*
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551, 247-250
Science
2017; 356(6336)
Nat Chem Biol.
1, 713–720 (2015)
Nat Commun
2016; 7: 11051.
Nat Cell Biol. 2013
15(12):1473-85.
Cell 2014 Feb 27
156(5):986-1001.
Nat Commun
2015; 6: 7139.
PNAS 2014
111(43) 15514-15519
PNAS 2014
111(23) E2404-E2413
J Neurosci. 2015
35(5): 2101–2111
Scientific Reports
5, 12298.
Cell Research
225, 707–725.
Oncogene
2014, 1–14 .
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Nature 2017
551, 247-250
Science
2017; 356(6336)
Nat Chem Biol.
1, 713–720 (2015)
Nat Commun
2016; 7: 11051.
Nat Cell Biol. 2013
15(12):1473-85.
Cell 2014 Feb 27
156(5):986-1001.
Nat Commun
2015; 6: 7139.
PNAS 2014
111(43) 15514-15519
PNAS 2014
111(23) E2404-E2413
J Neurosci. 2015
35(5): 2101–2111
Scientific Reports
5, 12298.
Cell Research
225, 707–725.
Oncogene
2014, 1–14 .
RESEARCH AREAS
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CATALOG NO.
PRODUCT NAME
APPLICATION
INFORMATION
A17142 AG-494
EGFR inhibitor
AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells.A17127 YHO-13177
BCRP/ABCG2 inhibitor YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2).A17154 SU-5408
VEGFR2 Kinase Inhibitor SU-5408, also known as VEGFR2 Kinase Inhibitor I, is a potent, cell-permeable inhibitor of mouse VEGFR2 kinase with IC50 value of 70nM.
A17162 ISCK03
c-kit inhibitor
ISCK03 is a potent c-kit inhibitor.A17125 CZC-25146
LRRK2 inhibitor
CZC-25146 is a potent LRRK2 inhibitor.A17129 BIO
GSK3 inhibitor
BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3α/β with IC50 value of 5 nM.A17134 XMD8-87
TNK2 Inhibitor
XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μMA17126 FX1
BCL6 inhibitor
FX1 is an inhibitor of the transcription factor B cell lymphoma 6 (BCL6) with IC50 value of ~35 μM.A17159 TRC051384
Hsp70 inducer
TRC051384 is an inducer of heat shock protein Hsp70.A17122 COH000
SUMO E1 Inhibitor
COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.Get Free Sample
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